Results 181 to 190 of about 1,498,374 (404)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

The kinetics of the interaction between the actin‐binding domain of α‐actinin and F‐actin [PDF]

, 1994
Philip A. Kuhlman, Jacqueline Ellis, David R. Critchley, Clive R. Bagshaw   +3 more
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration

, 2019
Guiping Wang, David Simon, Zhuhao Wu, Deanna M Belsky, Evan Heller, Melanie K. O’Rourke, Nicholas T. Hertz, Henrik Molina, Guisheng Zhong, Marc Tessier‐Lavigne, Xiaowei Zhuang   +10 more
openalex   +1 more source

Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms [PDF]

, 2020
Ottilie von Loeffelholz, Andrew G. Purkiss, Luyan Cao, Svend Kjær, Naoko Kogata, Guillaume Romet‐Lemonne, Michael Way, Carolyn A. Moores   +7 more
openalex   +1 more source

Actin, a Central Player in Cell Shape and Movement

Science, 2009
T. Pollard, J. Cooper
semanticscholar   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Rice TUTOU1 Encodes a Suppressor of cAMP Receptor-Like Protein That Is Important for Actin Organization and Panicle Development

, 2015
Jiaoteng Bai, Xudong Zhu, Qing Wang, Jian Zhang, Hongqi Chen, Guojun Dong, Lei Zhu, Huakun Zheng, Qingjun Xie, Jinqiang Nian, Fan Chen, Ying Fu, Qian Qian, Jianru Zuo   +13 more
openalex   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Actin in ribbons [PDF]

Nature, 1991
C, Schutt, U, Lindberg, J, Myslik
openaire   +2 more sources