Results 11 to 20 of about 1,498,374 (404)
Actin and Actin-Binding Proteins [PDF]
Cold Spring Harbor Perspectives in Biology, 2016 Organisms from all domains of life depend on filaments of the protein actin to provide structure and to support internal movements. Many eukaryotic cells use forces produced by actin polymerization for their motility, and myosin motor proteins use ATP hydrolysis to produce force on actin filaments.
T. Pollard
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The Actin Cytoskeleton and Actin-Based Motility [PDF]
Cold Spring Harbor Perspectives in Biology, 2018 The actin cytoskeleton-a collection of actin filaments with their accessory and regulatory proteins-is the primary force-generating machinery in the cell. It can produce pushing (protrusive) forces through coordinated polymerization of multiple actin filaments or pulling (contractile) forces through sliding actin filaments along bipolar filaments of ...
T. Svitkina
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Bacterial nucleators: actin' on actin [PDF]
Pathogens and Disease, 2015 The actin cytoskeleton is a key target of numerous microbial pathogens, including protozoa, fungi, bacteria and viruses. In particular, bacterial pathogens produce and deliver virulence effector proteins that hijack actin dynamics to enable bacterial invasion of host cells, allow movement within the host cytosol, facilitate intercellular spread or ...
Joana N, Bugalhão +2 more
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Actin, actin-binding proteins, and actin-related proteins in the nucleus [PDF]
Histochemistry and Cell Biology, 2016 Extensive research in the past decade has significantly broadened our view about the role actin plays in the life of the cell and added novel aspects to actin research. One of these new aspects is the discovery of the existence of nuclear actin which became evident only recently.
Kristó, Ildikó +4 more
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WH2 and proline-rich domains of WASP-family proteins collaborate to accelerate actin filament elongation. [PDF]
, 2017 WASP-family proteins are known to promote assembly of branched actin networks by stimulating the filament-nucleating activity of the Arp2/3 complex.
Akin, Orkun +6 more
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CAPG Is Required for Ebola Virus Infection by Controlling Virus Egress from Infected Cells
Viruses, 2022 The replication of Ebola virus (EBOV) is dependent upon actin functionality, especially at cell entry through macropinocytosis and at release of virus from cells.
Hiroyuki Mori +7 more
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The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility [PDF]
, 2013 Vaccinia virus dissemination relies on the N-WASP– ARP2/3 pathway, which mediates actin tail formation underneath cell-associated extracellular viruses (CEVs).
Alberts +79 more
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Cells, 2022 Glioblastoma (GBM) is a progressive and lethal brain cancer. Malignant control of actin and microtubule cytoskeletal mechanics facilitates two major GBM therapeutic resistance strategies—diffuse invasion and tumor microtube network formation.
Kathryn N. Becker +5 more
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A pharmacological cocktail for arresting actin dynamics in living cells. [PDF]
, 2011 The actin cytoskeleton is regulated by factors that influence polymer assembly, disassembly, and network rearrangement. Drugs that inhibit these events have been used to test the role of actin dynamics in a wide range of cellular processes.
Peng, Grace E +2 more
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LC3 and STRAP regulate actin filament assembly by JMY during autophagosome formation. [PDF]
, 2019 During autophagy, actin filament networks move and remodel cellular membranes to form autophagosomes that enclose and metabolize cytoplasmic contents. Two actin regulators, WHAMM and JMY, participate in autophagosome formation, but the signals linking ...
Axe +40 more
core +2 more sources