Results 11 to 20 of about 815,791 (269)

Frequent Manipulation of Resistance Training Variables Promotes Myofibrillar Spacing Changes in Resistance-Trained Individuals

Frontiers in Physiology, 2021
We sought to determine if manipulating resistance training (RT) variables differentially altered the expression of select sarcoplasmic and myofibril proteins as well as myofibrillar spacing in myofibers.
Carlton D. Fox, Paulo H. C. Mesquita, Joshua S. Godwin, Vitor Angleri, Felipe Damas, Bradley A. Ruple, Casey L. Sexton, Michael D. Brown, Andreas N. Kavazis, Kaelin C. Young, Kaelin C. Young, Carlos Ugrinowitsch, Cleiton A. Libardi, Michael D. Roberts, Michael D. Roberts   +14 more
doaj   +1 more source

Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42 [PDF]

Open Biology, 2020
Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and integrates with other signals during early embryogenesis remains poorly understood.
I-Chen Hung, Tsung-Ming Chen, Jing-Ping Lin, Yu-Ling Tai, Tang-Long Shen, Shyh-Jye Lee   +5 more
doaj   +1 more source

Identification of the Antifungal Metabolite Chaetoglobosin P From Discosia rubi Using a Cryptococcus neoformans Inhibition Assay: Insights Into Mode of Action and Biosynthesis

Frontiers in Microbiology, 2020
Cryptococcus neoformans is an important human pathogen with limited options for treatments. We have interrogated extracts from fungal fermentations to find Cryptococcus-inhibiting natural products using assays for growth inhibition, differential ...
Bruno Perlatti, Connie B. Nichols, Nan Lan, Philipp Wiemann, Colin J. B. Harvey, J. Andrew Alspaugh, Gerald F. Bills   +6 more
doaj   +1 more source

Interactions between β-arrestin proteins and the cytoskeletal system, and their relevance to neurodegenerative disorders

Frontiers in Endocrinology, 2023
β-arrestins, which have multiple cellular functions, were initially described as proteins that desensitize rhodopsin and other G protein-coupled receptors.
Tibor Szénási, Gábor Turu, Gábor Turu, László Hunyady, László Hunyady   +4 more
doaj   +1 more source

Mechanics and regulation of cytokinetic abscission

Frontiers in Cell and Developmental Biology, 2022
Cytokinetic abscission leads to the physical cut of the intercellular bridge (ICB) connecting the daughter cells and concludes cell division. In different animal cells, it is well established that the ESCRT-III machinery is responsible for the ...
Virginia Andrade, Virginia Andrade, Arnaud Echard   +2 more
doaj   +1 more source

Actin Remodeling Defects Leading to Autoinflammation and Immune Dysregulation

Frontiers in Immunology, 2021
A growing number of monogenic immune-mediated diseases have been related to genes involved in pathways of actin cytoskeleton remodeling. Increasing evidences associate cytoskeleton defects to autoinflammatory diseases and primary immunodeficiencies.
Riccardo Papa, Federica Penco, Stefano Volpi, Marco Gattorno   +3 more
doaj   +1 more source

Actin' like actin?

Trends in Cell Biology, 1996
The most biologically significant property of actin is its ability to self-associate and form two-stranded polymeric microfilaments. In living cells, these micro filaments form the actin cytoskeleton, essential for maintenance of the shape, passive mechanical properties and active motility of eukaryotic cells. Recently discovered actin-related proteins
R D, Mullins, J F, Kelleher, T D, Pollard   +2 more
openaire   +2 more sources

Class A scavenger receptors mediate cell adhesion via activation of Gi/o and formation of focal adhesion complexes

Journal of Lipid Research, 2002
Class A macrophage scavenger receptors (SR-A) are multifunctional receptors with roles in modified lipoprotein uptake, innate immunity, and macrophage adhesion.
Steven R. Post, Cecelia Gass, Stuart Rice, Dejan Nikolic, Heather Crump, Ginell R. Post   +5 more
doaj   +1 more source

Confinement Geometry Tunes Fascin-Actin Bundle Structures and Consequently the Shape of a Lipid Bilayer Vesicle

Frontiers in Molecular Biosciences, 2020
Depending on the physical and biochemical properties of actin-binding proteins, actin networks form different types of membrane protrusions at the cell periphery.
Yashar Bashirzadeh, Nadab H. Wubshet, Allen P. Liu, Allen P. Liu, Allen P. Liu, Allen P. Liu   +5 more
doaj   +1 more source

Intermediate Filaments in Cellular Mechanoresponsiveness: Mediating Cytoskeletal Crosstalk From Membrane to Nucleus and Back

Frontiers in Cell and Developmental Biology, 2022
The mammalian cytoskeleton forms a mechanical continuum that spans across the cell, connecting the cell surface to the nucleus via transmembrane protein complexes in the plasma and nuclear membranes. It transmits extracellular forces to the cell interior,
Anne-Betty Ndiaye, Gijsje H. Koenderink, Michal Shemesh   +2 more
doaj   +1 more source