Results 31 to 40 of about 976,237 (341)

Altered Cell Mechanics from the Inside: Dispersed Single Wall Carbon Nanotubes Integrate with and Restructure Actin

Journal of Functional Biomaterials, 2012
With a range of desirable mechanical and optical properties, single wall carbon nanotubes (SWCNTs) are a promising material for nanobiotechnologies. SWCNTs also have potential as biomaterials for modulation of cellular structures.
Mohammad F. Islam, Kris Noel Dahl, Gustavo K. Rohde, Mohammad R. K. Mofrad, Yu-Li Wang, Brian D. Holt, Hengameh Shams, Travis A. Horst, Saurav Basu, Andrew D. Rape   +9 more
doaj   +1 more source

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

Journal of Cell Biology, 1993
Granulation tissue fibroblasts (myofibroblasts) develop several ultrastructural and biochemical features of smooth muscle (SM) cells, including the presence of microfilament bundles and the expression of alpha-SM actin, the actin isoform typical of ...
Alexis Desmoulibre, A. Geinoz, Giulio Gabbian   +2 more
semanticscholar   +1 more source

Regulation of α-catenin conformation at cadherin adhesions

Journal of Biomechanical Science and Engineering, 2018
Cells in our body utilize a variety of adaptor proteins for transmitting context specific signals that arise from the cellular microenvironment. Adaptor proteins lack enzymatic activity and typically perform their function by acting as scaffolds that ...
Kabir H BISWAS
doaj   +1 more source

The actin cortex at a glance

Journal of Cell Science, 2018
Precisely controlled cell deformations are key to cell migration, division and tissue morphogenesis, and have been implicated in cell differentiation during development, as well as cancer progression.
P. Chugh, E. Paluch
semanticscholar   +1 more source

Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration

eLife, 2019
Axon degeneration sculpts neuronal connectivity patterns during development and is an early hallmark of several adult-onset neurodegenerative disorders. Substantial progress has been made in identifying effector mechanisms driving axon fragmentation, but
Guiping Wang, David J Simon, Zhuhao Wu, Deanna M Belsky, Evan Heller, Melanie K O'Rourke, Nicholas T Hertz, Henrik Molina, Guisheng Zhong, Marc Tessier-Lavigne, Xiaowei Zhuang   +10 more
doaj   +1 more source

Actin cortex architecture regulates cell surface tension

Nature Cell Biology, 2017
Animal cell shape is largely determined by the cortex, a thin actin network underlying the plasma membrane in which myosin-driven stresses generate contractile tension. Tension gradients result in local contractions and drive cell deformations.
P. Chugh, Andrew G. Clark, Matthew B. Smith, D. Cassani, K. Dierkes, Anan Ragab, Philippe P Roux, G. Charras, G. Salbreux, E. Paluch   +9 more
semanticscholar   +1 more source

Differential requirements for cyclase-associated protein (CAP) in actin-dependent processes of Toxoplasma gondii

eLife, 2019
Toxoplasma gondii contains a limited subset of actin binding proteins. Here we show that the putative actin regulator cyclase-associated protein (CAP) is present in two different isoforms and its deletion leads to significant defects in some but not all ...
Alex Hunt, Matthew Robert Geoffrey Russell, Jeanette Wagener, Robyn Kent, Romain Carmeille, Christopher J Peddie, Lucy Collinson, Aoife Heaslip, Gary E Ward, Moritz Treeck   +9 more
doaj   +1 more source

Effects of cytochalasin and phalloidin on actin

Journal of Cell Biology, 1987
C YTOCHALASINS and phalloidins are two groups of small, naturally occurring organic molecules that bind to actin and alter its polymerization. They have been widely used to study the role of actin in biological processes and as models for actin-binding ...
J. Cooper
semanticscholar   +1 more source

Actin in development

Mechanisms of Development, 2003
1. From molecules to morphologyMetazoan development is often viewed as a series ofinformation processing events in which the genomecomputes where and when to synthesize particular geneproducts. Importantly, development is also a feat ofengineering in which genetic information is used to changecell shape and cell–cell interactions to generate form ...
Buzz Baum, António Jacinto
openaire   +3 more sources

Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape

Journal of Cell Biology, 1993
Microtubules are long, proteinaceous filaments that perform structural functions in eukaryotic cells by defining cellular shape and serving as tracks for intracellular motor proteins.
F. Gittes, B. Mickey, J. Nettleton, J. Howard   +3 more
semanticscholar   +1 more source