Results 31 to 40 of about 1,498,374 (404)

Actomyosin Contractility in the Generation and Plasticity of Axons and Dendritic Spines

open access: yesCells, 2020
Actin and non-muscle myosins have long been known to play important roles in growth cone steering and neurite outgrowth. More recently, novel functions for non-muscle myosin have been described in axons and dendritic spines.
Marina Mikhaylova   +2 more
doaj   +1 more source

SARM1 Suppresses Axon Branching Through Attenuation of Axonal Cytoskeletal Dynamics

open access: yesFrontiers in Molecular Neuroscience, 2022
Axon branching is a fundamental aspect of neuronal morphogenesis, neuronal circuit formation, and response of the nervous system to injury. Sterile alpha and TIR motif containing 1 (SARM1) was initially identified as promoting Wallerian degeneration of ...
Andrea Ketschek   +3 more
doaj   +1 more source

Copurification of actin and desmin from chicken smooth muscle and their copolymerization in vitro to intermediate filaments [PDF]

open access: yes, 1979
Desmin is a 50,000-mol wt protein that is enriched along with 100-A filaments in chicken gizzard that has been extracted with 1 M KI. Although 1 M KI removes most of the actin from gizzard, a small fraction of this protein remains persistently insoluble,
Hubbard, Bruce D., Lazarides, Elias
core   +3 more sources

Phosphorylation acts positively and negatively to regulate MRTF-A subcellular localisation and activity

open access: yeseLife, 2016
The myocardin-related transcription factors (MRTF-A and MRTF-B) regulate cytoskeletal genes through their partner transcription factor SRF. The MRTFs bind G-actin, and signal-regulated changes in cellular G-actin concentration control their nuclear ...
Richard Panayiotou   +6 more
doaj   +1 more source

Nucleotide-dependent activities of FtsA regulate the early establishment of a functional divisome during the Escherichia coli cell cycle

open access: yesFrontiers in Microbiology, 2023
During cell division in Escherichia coli, the highly conserved tubulin homolog FtsZ polymerizes and assembles into a ring-like structure, called the Z-ring, at the site of septation.
Josiah J. Morrison   +6 more
doaj   +1 more source

A Rho family GTPase controls actin dynamics and tip growth via two counteracting downstream pathways in pollen tubes. [PDF]

open access: yes, 2005
Tip growth in neuronal cells, plant cells, and fungal hyphae is known to require tip-localized Rho GTPase, calcium, and filamentous actin (F-actin), but how they interact with each other is unclear.
Dowd, Peter   +6 more
core   +3 more sources

Novel Actin Cytoskeleton. Actin Tubules.

open access: yesCell Structure and Function, 2000
In spores of Dictyostelium discoideum three actin filaments are bundled to form a novel tubular structure and the tubules are then organized into rods. These tubular structures we will term actin tubules. Actin tubules are reconstructed from the supernatant of spore homogenates, while the usual actin filaments were bundled after incubation of ...
M, Sameshima   +4 more
openaire   +3 more sources

The actin cortex at a glance

open access: yesJournal of Cell Science, 2018
Precisely controlled cell deformations are key to cell migration, division and tissue morphogenesis, and have been implicated in cell differentiation during development, as well as cancer progression.
P. Chugh, E. Paluch
semanticscholar   +1 more source

miR-142 orchestrates a network of actin cytoskeleton regulators during megakaryopoiesis

open access: yeseLife, 2014
Genome-encoded microRNAs (miRNAs) provide a posttranscriptional regulatory layer that controls the differentiation and function of various cellular systems, including hematopoietic cells. miR-142 is one of the most prevalently expressed miRNAs within the
Elik Chapnik   +16 more
doaj   +1 more source

Siglec-8 Signals Through a Non-Canonical Pathway to Cause Human Eosinophil Death In Vitro

open access: yesFrontiers in Immunology, 2021
Sialic acid-binding immunoglobulin-like lectin (Siglec)-8 is a glycan-binding receptor bearing immunoreceptor tyrosine-based inhibitory and switch motifs (ITIM and ITSM, respectively) that is selectively expressed on eosinophils, mast cells, and, to a ...
Daniela J. Carroll   +3 more
doaj   +1 more source

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