Results 41 to 50 of about 1,498,374 (404)

Actin cortex architecture regulates cell surface tension

Nature Cell Biology, 2017
Animal cell shape is largely determined by the cortex, a thin actin network underlying the plasma membrane in which myosin-driven stresses generate contractile tension. Tension gradients result in local contractions and drive cell deformations.
P. Chugh, Andrew G. Clark, Matthew B. Smith, D. Cassani, K. Dierkes, Anan Ragab, Philippe P Roux, G. Charras, G. Salbreux, E. Paluch   +9 more
semanticscholar   +1 more source

High Temporal Resolution 3D Live-Cell Imaging of Budding Yeast Meiosis Defines Discontinuous Actin/Telomere-Mediated Chromosome Motion, Correlated Nuclear Envelope Deformation and Actin Filament Dynamics

Frontiers in Cell and Developmental Biology, 2021
Chromosome movement is prominent at mid-meiotic prophase and is proposed to enhance the efficiency and/or stringency of homolog pairing and/or to help prevent or resolve topological entanglements.
Tadasu Nozaki, Frederick Chang, Beth Weiner, Nancy Kleckner   +3 more
doaj   +1 more source

On the dynamics of the microfilament system in HeLa cells [PDF]

, 1982
We measured the pools of unpolymerized and filamentous actin in homogenates of HeLa cells made in several different lysis buffers, as well as after treatment of cells with a variety of chemicals or trypsin, and after adenovirus (type 2) infection.
Blikstad, Ingrid, Carlsson, Lars
core   +3 more sources

Effects of cytochalasin and phalloidin on actin

Journal of Cell Biology, 1987
C YTOCHALASINS and phalloidins are two groups of small, naturally occurring organic molecules that bind to actin and alter its polymerization. They have been widely used to study the role of actin in biological processes and as models for actin-binding ...
J. Cooper
semanticscholar   +1 more source

Wound Repair of the Cell Membrane: Lessons from Dictyostelium Cells

Cells
The cell membrane is frequently subjected to damage, either through physical or chemical means. The swift restoration of the cell membrane’s integrity is crucial to prevent the leakage of intracellular materials and the uncontrolled influx of ...
Shigehiko Yumura
doaj   +1 more source

Tugging at the Heart Strings: The Septin Cytoskeleton in Heart Development and Disease

Journal of Cardiovascular Development and Disease, 2020
Septin genes were originally identified in budding yeast in 1971. Since their original discovery, at least 13 mammalian genes have now been found, which give rise to a vast array of alternatively spliced proteins that display unique spatial-temporal ...
Kelsey Moore, Reece Moore, Christina Wang, Russell A. Norris   +3 more
doaj   +1 more source

The actin binding proteins cortactin and HS1 are dispensable for platelet actin nodule and megakaryocyte podosome formation [PDF]

, 2016
A dynamic, properly organised actin cytoskeleton is critical for the production and haemostatic function of platelets. The Wiskott Aldrich Syndrome protein (WASp) and Actin-Related Proteins 2 & 3 Complex (Arp2/3 complex) are critical mediators of ...
Bem, Danai, Finney, Brenda, Machesky, Laura M., Poulter, Natalie S., Thomas, Steven G., Watson, Stephen P.   +5 more
core   +4 more sources

Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape

Journal of Cell Biology, 1993
Microtubules are long, proteinaceous filaments that perform structural functions in eukaryotic cells by defining cellular shape and serving as tracks for intracellular motor proteins.
F. Gittes, B. Mickey, J. Nettleton, J. Howard   +3 more
semanticscholar   +1 more source

A role for tunneling nanotubes in virus spread

Frontiers in Microbiology
Tunneling nanotubes (TNTs) are actin-rich intercellular conduits that mediate distant cell-to-cell communication and enable the transfer of various cargos, including proteins, organelles, and virions.
Weimiao Lv, Weimiao Lv, Weimiao Lv, Zichen Li, Zichen Li, Shule Wang, Jingyi He, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang   +9 more
doaj   +1 more source

Visualization of Endothelial Actin Cytoskeleton in the Mouse Retina [PDF]

, 2012
Angiogenesis requires coordinated changes in cell shape of endothelial cells (ECs), orchestrated by the actin cytoskeleton. The mechanisms that regulate this rearrangement in vivo are poorly understood - largely because of the difficulty to visualize ...
Alessia Fraccaroli, Attila Aszodi, Claudio A Franco, Eloi Montanez, Emanuel Rognoni, Filipa Neto, Holger Gerhardt, Holger Gerhardt, Markus Rehberg, Roland Wedlich-Söldner, Ulrich Pohl   +10 more
core   +5 more sources