Results 111 to 120 of about 311,782 (303)

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

open access: yesAdvanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram   +5 more
wiley   +1 more source

The septin cytoskeleton facilitates membrane retraction during motility and blebbing. [PDF]

open access: yes, 2012
Increasing evidence supports a critical role for the septin cytoskeleton at the plasma membrane during physiological processes including motility, formation of dendritic spines or cilia, and phagocytosis.
Chen, Yi-Chun M   +3 more
core  

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

open access: yesAdvanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt   +2 more
wiley   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

open access: yesAdvanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim   +4 more
wiley   +1 more source

A T-lymphoma transmembrane glycoprotein (gp180) is linked to the cytoskeletal protein, fodrin. [PDF]

open access: yes, 1985
A major mouse T-lymphoma surface glycoprotein (gp180) has been identified by labeling cells with 125I and [3H]glucosamine. After ligand-induced receptor patching and/or capping, the amount of gp 180 in the membrane-associated cytoskeleton fraction ...
Bourguignon, LY   +3 more
core  

Fluorescent Nanodiamonds Based Theranostic Platform for pH‐Sensitive Drug Delivery and Quantum Sensing

open access: yesAdvanced Functional Materials, EarlyView.
A multifunctional nanodiamond platform enables pH‐triggered Diazoxide (DZX) delivery and quantum sensing of subcellular radical dynamics in triple‐negative breast cancer cells. Diamond relaxometry revealed reduced lysosomal radicals during DZX‐induced mitochondrial radical elevation, providing insights into redox modulation and organelle‐ resolved ...
Kaiqui Wu   +8 more
wiley   +1 more source

The Actin Cytoskeleton Controls the Activation of Invariant Natural Killer T Cells by Fine-Tuning CD1d Nanoscale Aggregation on Antigen Presenting Cells [PDF]

open access: bronze, 2014
Juan A. Torreño-Pina   +5 more
openalex   +1 more source

Multifunctional, Flexible and Interactive PVDF Fibers with Tunable Conductivity via CNT Coatings for Sensing and Smart Textile Applications

open access: yesAdvanced Functional Materials, EarlyView.
A two‐step fabrication strategy combines electrospinning with electrophoretic deposition of carbon nanotubes to produce conductive, porous PVDF fiber mats. These flexible composites serve as multifunctional sensors, capable of detecting pressure, motion, respiration, and temperature.
Michał Kopacz   +7 more
wiley   +1 more source

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