Results 91 to 100 of about 75,213 (335)
Dipotassium 4,4′-(hexane-3,4-diyl)bis(benzenesulfonate) dihydrate
Acta Crystallographica Section E, 2008 The anion of the title compound, also called sygethin dihydrate, 2K+·C18H20O6S22−·2H2O, has crystallographic inversion symmetry. The K+ cation is surrounded by eight O atoms in a distorted cubic coordination geometry, forming extended K ...
Liana Orola +3 more
doaj +1 more source
シロイヌナズナアクチンアイソフォームの分子細胞生物学的研究 [PDF]
, 2018 この博士論文は内容の要約のみの公開（または一部非公開）になっています筑波大学 (University of Tsukuba ...
KIJIMA Saku, 貴嶋 紗久
core +1 more source
Geometric pumping induced by shear flow in dilute liquid crystalline polymer solutions [PDF]
, 2014 We investigate nonlinear rheology of dilute liquid crystalline polymer solutions under time dependent two-directional shear flow. We analyze the Smoluchowski equation, which describes the dynamics of the orientation of a liquid crystalline polymer, by ...
de Gennes P. G. +4 more
core +2 more sources
Actin cytoskeleton: Thinking globally, actin’ locally [PDF]
Current Biology, 2000 A class of proteins dubbed pipmodulins bind to and sequester the phospholipid PIP2 in the plasma membrane. Local release of PIP2 controls actin dynamics in specific subcellular regions and plays a critical role in regulating actin-based cell motility and morphogenesis.
Lanier, Lorene M., Gertler, Frank
openaire +4 more sources
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Vimentin downregulation is an inherent feature of murine erythropoiesis and occurs independently of lineage [PDF]
, 1990 In mammalian erythropoiesis, the mature cells of the primitive lineage remain nucleated while those of the definitive lineage are anuclear. One of the molecular and structural changes that precedes enucleation in cells of the definitive lineage is the ...
Lazarides, Elias +2 more
core
Large scale analysis of protein stability in OMIM disease related human protein variants [PDF]
, 2016 Modern genomic techniques allow to associate several Mendelian human diseases to single residue variations in different proteins. Molecular mechanisms explaining the relationship among genotype and phenotype are still under debate.
Aggazio, Francesco +5 more
core +3 more sources
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Nuclear actin and myosins in adenovirus infection [PDF]
, 2015 Adenovirus serotypes have been shown to cause drastic changes in nuclear organization, including the transcription machinery, during infection. This ability of adenovirus to subvert transcription in the host cell facilitates viral replication.
De Lanerolle, Primal +2 more
core +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source