Results 11 to 20 of about 25,337 (247)
Bacterial nucleators: actin' on actin [PDF]
Pathogens and Disease, 2015 The actin cytoskeleton is a key target of numerous microbial pathogens, including protozoa, fungi, bacteria and viruses. In particular, bacterial pathogens produce and deliver virulence effector proteins that hijack actin dynamics to enable bacterial invasion of host cells, allow movement within the host cytosol, facilitate intercellular spread or ...
Joana N, Bugalhão +2 more
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Different translation dynamics of β- and γ-actin regulates cell migration
eLife, 2021 β- and γ-cytoplasmic actins are ubiquitously expressed in every cell type and are nearly identical at the amino acid level but play vastly different roles in vivo. Their essential roles in embryogenesis and mesenchymal cell migration critically depend on
Pavan Vedula +7 more
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Structure and function of Plasmodium actin II in the parasite mosquito stages.
PLoS Pathogens, 2023 Actins are filament-forming, highly-conserved proteins in eukaryotes. They are involved in essential processes in the cytoplasm and also have nuclear functions.
Andrea J Lopez +10 more
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Frontiers in Pharmacology, 2022 The cytoplasmic actin isoforms (β- and γ-actins) contribute greatly to cellular processes such as cel-cell and cell-matrix interactions, as well as cell polarization, motility and division. Distinct isoforms modulations are linked to serious pathologies,
V. B. Dugina +3 more
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PLoS ONE, 2014 The pressure tolerance of monomeric α-actin proteins from the deep-sea fish Coryphaenoides armatus and C. yaquinae was compared to that of non-deep-sea fish C.
Nobuhiko Wakai +3 more
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Structural differences explain diverse functions of Plasmodium actins.
PLoS Pathogens, 2014 Actins are highly conserved proteins and key players in central processes in all eukaryotic cells. The two actins of the malaria parasite are among the most divergent eukaryotic actins and also differ from each other more than isoforms in any other ...
Juha Vahokoski +11 more
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Cytoplasmic actin is an extracellular insect immune factor which is secreted upon immune challenge and mediates phagocytosis and direct killing of bacteria, and is a Plasmodium Antagonist. [PDF]
PLoS Pathogens, 2015 Actin is a highly versatile, abundant, and conserved protein, with functions in a variety of intracellular processes. Here, we describe a novel role for insect cytoplasmic actin as an extracellular pathogen recognition factor that mediates antibacterial ...
Simone L Sandiford +5 more
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The Role of non-muscle actin paralogs in cell cycle progression and proliferation
European Journal of Cell Biology, 2023 Uncontrolled cell proliferation leads to several pathologies, including cancer. Thus, this process must be tightly regulated. The cell cycle accounts for cell proliferation, and its progression is coordinated with changes in cell shape, for which ...
Estera Jeruzalska, Antonina J. Mazur
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Purification of Human Cytoplasmic Actins From Saccharomyces cerevisiae
Bio-Protocol, 2023 Eukaryotic cells rely on actin to support cellular structure, motility, transport, and a wide variety of other cytoplasmic functions and nuclear activities.
Brian Haarer +2 more
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Trends in Cell Biology, 1996 The most biologically significant property of actin is its ability to self-associate and form two-stranded polymeric microfilaments. In living cells, these micro filaments form the actin cytoskeleton, essential for maintenance of the shape, passive mechanical properties and active motility of eukaryotic cells. Recently discovered actin-related proteins
R D, Mullins +2 more
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