Results 11 to 20 of about 243,847 (379)

Structural differences explain diverse functions of Plasmodium actins.

open access: yesPLoS Pathogens, 2014
Actins are highly conserved proteins and key players in central processes in all eukaryotic cells. The two actins of the malaria parasite are among the most divergent eukaryotic actins and also differ from each other more than isoforms in any other ...
Juha Vahokoski   +11 more
doaj   +2 more sources

Emerging Functions of Actins and Actin Binding Proteins in Trypanosomatids

open access: yesFrontiers in Cell and Developmental Biology, 2020
Actin is the major protein constituent of the cytoskeleton that performs wide range of cellular functions. It exists in monomeric and filamentous forms, dynamics of which is regulated by a large repertoire of actin binding proteins. However, not much was
Chhitar M. Gupta   +4 more
doaj   +2 more sources

The actinome of Dictyostelium discoideum in comparison to actins and actin-related proteins from other organisms. [PDF]

open access: yesPLoS ONE, 2008
Actin belongs to the most abundant proteins in eukaryotic cells which harbor usually many conventional actin isoforms as well as actin-related proteins (Arps).
Jayabalan M Joseph   +8 more
doaj   +2 more sources

Diverse cytomotive actins and tubulins share a polymerization switch mechanism conferring robust dynamics

open access: yesScience Advances, 2023
Protein filaments are used in myriads of ways to organize other molecules within cells. Some filament-forming proteins couple the hydrolysis of nucleotides to their polymerization cycle, thus powering the movement of other molecules.
J. Wagstaff   +6 more
semanticscholar   +1 more source

Unique and redundant functions of cytoplasmic actins and nonmuscle myosin II isoforms at epithelial junctions

open access: yesAnnals of the New York Academy of Sciences, 2022
The integrity and functions of epithelial barriers depend on the formation of adherens junctions (AJs) and tight junctions (TJs). A characteristic feature of AJs and TJs is their association with the cortical cytoskeleton composed of actin filaments and ...
A. Ivanov   +3 more
semanticscholar   +1 more source

Reconstitution of a minimal motility system based on Spiroplasma swimming by two bacterial actins in a synthetic minimal bacterium

open access: yesScience Advances, 2022
Motility is one of the most important features of life, but its evolutionary origin remains unknown. In this study, we focused on Spiroplasma, commensal, or parasitic bacteria.
Hana Kiyama   +4 more
semanticscholar   +1 more source

The Cytoplasmic Actins in the Regulation of Endothelial Cell Function

open access: yesInternational Journal of Molecular Sciences, 2021
The primary function of the endothelial cells (EC) lining the inner surface of all vessels is to regulate permeability of vascular walls and to control exchange between circulating blood and tissue fluids of organs.
V. Dugina   +3 more
semanticscholar   +1 more source

Bacterial nucleators: actin' on actin [PDF]

open access: yesPathogens and Disease, 2015
The actin cytoskeleton is a key target of numerous microbial pathogens, including protozoa, fungi, bacteria and viruses. In particular, bacterial pathogens produce and deliver virulence effector proteins that hijack actin dynamics to enable bacterial invasion of host cells, allow movement within the host cytosol, facilitate intercellular spread or ...
Joana N, Bugalhão   +2 more
openaire   +2 more sources

Different translation dynamics of β- and γ-actin regulates cell migration

open access: yeseLife, 2021
β- and γ-cytoplasmic actins are ubiquitously expressed in every cell type and are nearly identical at the amino acid level but play vastly different roles in vivo. Their essential roles in embryogenesis and mesenchymal cell migration critically depend on
Pavan Vedula   +7 more
doaj   +1 more source

Actin, actin-binding proteins, and actin-related proteins in the nucleus [PDF]

open access: yesHistochemistry and Cell Biology, 2016
Extensive research in the past decade has significantly broadened our view about the role actin plays in the life of the cell and added novel aspects to actin research. One of these new aspects is the discovery of the existence of nuclear actin which became evident only recently.
Kristó, Ildikó   +4 more
openaire   +3 more sources

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