Elevated barometric pressure suppresses cell proliferation by delaying the G2/M phase and weakening integrin-mediated cell adhesion and actin assembly [PDF]
Archives of Biological Sciences, 2023 Human cells are continuously exposed to various stress factors in their physiological environment. Evidence suggests that certain mechanical stress can affect cell cycle progression and cell proliferation. However, the signaling pathways involved in this
Son Gwang-ic +5 more
doaj +1 more source
Dental Research Journal, 2021 Background: Odontogenic cysts and tumors exhibit varying degrees of aggressiveness in their biological behavior. Odontogenic keratocyst (OKC), dentigerous cyst (DC), ameloblastoma are most common odontogenic cysts and tumors to occur in the oral cavity ...
V V Anusai +5 more
doaj +1 more source
Scientific Reports, 2021 We have recently found that β-actin-like protein 2 (actbl2) forms complexes with gelsolin in human melanoma cells and can polymerize. Phylogenetic and bioinformatic analyses showed that actbl2 has a common origin with two non-muscle actins, which share a
Natalia Malek +5 more
doaj +1 more source
An In Silico Investigation of the Molecular Interactions between Volatile Anesthetics and Actin
Pharmaceuticals, 2023 Volatile anesthetics (VAs) are medicinal chemistry compounds commonly used to enable surgical procedures for patients who undergo painful treatments and can be partially or fully sedated, remaining in an unconscious state during the operation.
Barbara Truglia +7 more
doaj +1 more source
Immunohistochemical analysis of α-SMA and GFAP expression in liver stellate cells [PDF]
Vojnosanitetski Pregled, 2006 Background/Aim. Liver stellate cells play an important role in hepatic fibrosis, and its progression to cirrhosis. These cells show immunoreactivity with different monoclonal antibodies amongst which the commonest are α-smooth muscle actin (α-SMA) and ...
Tomanović Nada +2 more
doaj +1 more source
Bacterial nucleators: actin' on actin [PDF]
Pathogens and Disease, 2015 The actin cytoskeleton is a key target of numerous microbial pathogens, including protozoa, fungi, bacteria and viruses. In particular, bacterial pathogens produce and deliver virulence effector proteins that hijack actin dynamics to enable bacterial invasion of host cells, allow movement within the host cytosol, facilitate intercellular spread or ...
Joana N, Bugalhão +2 more
openaire +2 more sources
Evolutionarily divergent, unstable filamentous actin is essential for gliding motility in apicomplexan parasites. [PDF]
PLoS Pathogens, 2011 Apicomplexan parasites rely on a novel form of actin-based motility called gliding, which depends on parasite actin polymerization, to migrate through their hosts and invade cells.
Kristen M Skillman +5 more
doaj +1 more source
Different translation dynamics of β- and γ-actin regulates cell migration
eLife, 2021 β- and γ-cytoplasmic actins are ubiquitously expressed in every cell type and are nearly identical at the amino acid level but play vastly different roles in vivo. Their essential roles in embryogenesis and mesenchymal cell migration critically depend on
Pavan Vedula +7 more
doaj +1 more source
Actin, actin-binding proteins, and actin-related proteins in the nucleus [PDF]
Histochemistry and Cell Biology, 2016 Extensive research in the past decade has significantly broadened our view about the role actin plays in the life of the cell and added novel aspects to actin research. One of these new aspects is the discovery of the existence of nuclear actin which became evident only recently.
Kristó, Ildikó +4 more
openaire +3 more sources
Developmental atlas of appendicularian Oikopleura dioica actins provides new insights into the evolution of the notochord and the cardio-paraxial muscle in chordates. [PDF]
, 2023 Locomotion by tail beating powered by a system of bilateral paraxial muscle and notochord is likely one of the key evolutionary innovations that facilitated the origin and radiation of chordates.
Almazán, Alba +3 more
core +1 more source