An In Silico Investigation of the Molecular Interactions between Volatile Anesthetics and Actin
Pharmaceuticals, 2023 Volatile anesthetics (VAs) are medicinal chemistry compounds commonly used to enable surgical procedures for patients who undergo painful treatments and can be partially or fully sedated, remaining in an unconscious state during the operation.
Barbara Truglia +7 more
doaj +1 more source
Immunohistochemical analysis of α-SMA and GFAP expression in liver stellate cells [PDF]
Vojnosanitetski Pregled, 2006 Background/Aim. Liver stellate cells play an important role in hepatic fibrosis, and its progression to cirrhosis. These cells show immunoreactivity with different monoclonal antibodies amongst which the commonest are α-smooth muscle actin (α-SMA) and ...
Tomanović Nada +2 more
doaj +1 more source
Bacterial nucleators: actin' on actin [PDF]
Pathogens and Disease, 2015 The actin cytoskeleton is a key target of numerous microbial pathogens, including protozoa, fungi, bacteria and viruses. In particular, bacterial pathogens produce and deliver virulence effector proteins that hijack actin dynamics to enable bacterial invasion of host cells, allow movement within the host cytosol, facilitate intercellular spread or ...
Joana N, Bugalhão +2 more
openaire +2 more sources
Evolutionarily divergent, unstable filamentous actin is essential for gliding motility in apicomplexan parasites. [PDF]
PLoS Pathogens, 2011 Apicomplexan parasites rely on a novel form of actin-based motility called gliding, which depends on parasite actin polymerization, to migrate through their hosts and invade cells.
Kristen M Skillman +5 more
doaj +1 more source
Different translation dynamics of β- and γ-actin regulates cell migration
eLife, 2021 β- and γ-cytoplasmic actins are ubiquitously expressed in every cell type and are nearly identical at the amino acid level but play vastly different roles in vivo. Their essential roles in embryogenesis and mesenchymal cell migration critically depend on
Pavan Vedula +7 more
doaj +1 more source
Structure and function of Plasmodium actin II in the parasite mosquito stages.
PLoS Pathogens, 2023 Actins are filament-forming, highly-conserved proteins in eukaryotes. They are involved in essential processes in the cytoplasm and also have nuclear functions.
Andrea J Lopez +10 more
doaj +1 more source
Frontiers in Pharmacology, 2022 The cytoplasmic actin isoforms (β- and γ-actins) contribute greatly to cellular processes such as cel-cell and cell-matrix interactions, as well as cell polarization, motility and division. Distinct isoforms modulations are linked to serious pathologies,
V. B. Dugina +3 more
doaj +1 more source
Investigation of mass graves in the Churchyard of St. Gertrude’s, Riga, Latvia [PDF]
, 2011 What determines the magnitude of attentional capture by deviant sound events? We combined the cross-modal oddballdistraction paradigm with sequence learning to address this question.
Actins, Andris +5 more
core +8 more sources
PLoS ONE, 2014 The pressure tolerance of monomeric α-actin proteins from the deep-sea fish Coryphaenoides armatus and C. yaquinae was compared to that of non-deep-sea fish C.
Nobuhiko Wakai +3 more
doaj +1 more source
Cytoplasmic actin is an extracellular insect immune factor which is secreted upon immune challenge and mediates phagocytosis and direct killing of bacteria, and is a Plasmodium Antagonist. [PDF]
PLoS Pathogens, 2015 Actin is a highly versatile, abundant, and conserved protein, with functions in a variety of intracellular processes. Here, we describe a novel role for insect cytoplasmic actin as an extracellular pathogen recognition factor that mediates antibacterial ...
Simone L Sandiford +5 more
doaj +1 more source