Structural Differences Explain Diverse Functions of Plasmodium Actins
PLoS Pathogens, 2014 Actins are highly conserved proteins and key players in central processes in all eukaryotic cells. The two actins of the malaria parasite are among the most divergent eukaryotic actins and also differ from each other more than isoforms in any other ...
Juha Vahokoski +2 more
exaly +4 more sources
The Actinome of Dictyostelium discoideum in Comparison to Actins and Actin-Related Proteins from Other Organisms [PDF]
PLoS ONE, 2008 Actin belongs to the most abundant proteins in eukaryotic cells which harbor usually many conventional actin isoforms as well as actin-related proteins (Arps).
Petra Fey +2 more
exaly +4 more sources
Differential Support of Aspergillus fumigatus Morphogenesis by Yeast and Human Actins [PDF]
PLoS ONE, 2015 The actin cytoskeleton is highly conserved among eukaryotes and is essential for cellular processes regulating growth and differentiation. In fungi, filamentous actin (F-actin) orchestrates hyphal tip structure and extension via organization of exocytic ...
Jarrod R Fortwendel
exaly +3 more sources
Dynamical features of smooth muscle actin pathological mutants: The arginine-257(258)-Cysteine cases [PDF]
Computational and Structural Biotechnology JournalThe R257(8)C mutation in smooth muscle actins, ACTG2 and ACTA2, is the most frequent cause of severe genetic diseases: namely, visceral myopathy, and familial thoracic aortic aneurysms and dissections, which respectively, stem from impairment of the ...
F. Chiappori +4 more
doaj +2 more sources
Antioxidants, 2021 The human mutant cardiac α-actins p.A295S or p.R312H and p.E361G, correlated with hypertrophic or dilated cardiomyopathy, respectively, were expressed by the baculovirus/Sf21 insect cell system and purified to homogeneity.
Constanze Erdmann +10 more
doaj +2 more sources
Conservation of conformational dynamics across prokaryotic actins.
PLoS Computational Biology, 2019 The actin family of cytoskeletal proteins is essential to the physiology of virtually all archaea, bacteria, and eukaryotes. While X-ray crystallography and electron microscopy have revealed structural homologies among actin-family proteins, these ...
Natalie Ng +3 more
doaj +2 more sources
PLoS ONE, 2014 The pressure tolerance of monomeric α-actin proteins from the deep-sea fish Coryphaenoides armatus and C. yaquinae was compared to that of non-deep-sea fish C.
Nobuhiko Wakai +3 more
doaj +2 more sources
Naa80 is required for actin N-terminal acetylation and normal hearing in zebrafish [PDF]
Life Science AllianceA zebrafish knockout model of the N-terminal acetyltransferase Naa80 demonstrates that this enzyme is required for actin N-terminal acetylation and normal inner ear development. Actin is a critical component of the eukaryotic cytoskeleton.
Rasmus Ree +6 more
doaj +2 more sources
Electrochemically modulated single-molecule localization microscopy for in vitro imaging cytoskeletal protein structures [PDF]
NanophotonicsA new concept of electrochemically modulated single-molecule localization super-resolution imaging is developed. Applications of single-molecule localization super-resolution microscopy have been limited due to insufficient availability of qualified ...
Lei Chenghong, Hu Dehong
doaj +2 more sources
Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Thioacetamide (TAA) was administered to induce an animal model of liver disease with secondary splenomegaly to assess the mechanisms underlying the effects of rapamycin and filgrastim when taken separately or in combination on the ...
Shaimaa Abdelrahman +2 more
doaj +1 more source