Structural Differences Explain Diverse Functions of Plasmodium Actins [PDF]
PLoS Pathogens, 2014 Actins are highly conserved proteins and key players in central processes in all eukaryotic cells. The two actins of the malaria parasite are among the most divergent eukaryotic actins and also differ from each other more than isoforms in any other ...
Inari Kursula +2 more
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Differential Support of Aspergillus fumigatus Morphogenesis by Yeast and Human Actins [PDF]
PLoS ONE, 2015 The actin cytoskeleton is highly conserved among eukaryotes and is essential for cellular processes regulating growth and differentiation. In fungi, filamentous actin (F-actin) orchestrates hyphal tip structure and extension via organization of exocytic ...
Jarrod Fortwendel
exaly +3 more sources
The Actinome of Dictyostelium discoideum in Comparison to Actins and Actin-Related Proteins from Other Organisms [PDF]
PLoS ONE, 2008 Actin belongs to the most abundant proteins in eukaryotic cells which harbor usually many conventional actin isoforms as well as actin-related proteins (Arps).
Angelika Noegel +2 more
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Conservation of conformational dynamics across prokaryotic actins
PLoS Computational Biology, 2019 The actin family of cytoskeletal proteins is essential to the physiology of virtually all archaea, bacteria, and eukaryotes. While X-ray crystallography and electron microscopy have revealed structural homologies among actin-family proteins, these ...
Handuo Shi +2 more
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Dynamical features of smooth muscle actin pathological mutants: The arginine-257(258)-Cysteine cases [PDF]
Computational and Structural Biotechnology JournalThe R257(8)C mutation in smooth muscle actins, ACTG2 and ACTA2, is the most frequent cause of severe genetic diseases: namely, visceral myopathy, and familial thoracic aortic aneurysms and dissections, which respectively, stem from impairment of the ...
F. Chiappori +4 more
doaj +2 more sources
PLoS ONE, 2014 The pressure tolerance of monomeric α-actin proteins from the deep-sea fish Coryphaenoides armatus and C. yaquinae was compared to that of non-deep-sea fish C.
Nobuhiko Wakai +3 more
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Naa80 is required for actin N-terminal acetylation and normal hearing in zebrafish [PDF]
Life Science AllianceA zebrafish knockout model of the N-terminal acetyltransferase Naa80 demonstrates that this enzyme is required for actin N-terminal acetylation and normal inner ear development. Actin is a critical component of the eukaryotic cytoskeleton.
Rasmus Ree +6 more
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Electrochemically modulated single-molecule localization microscopy for in vitro imaging cytoskeletal protein structures [PDF]
NanophotonicsA new concept of electrochemically modulated single-molecule localization super-resolution imaging is developed. Applications of single-molecule localization super-resolution microscopy have been limited due to insufficient availability of qualified ...
Lei Chenghong, Hu Dehong
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Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Thioacetamide (TAA) was administered to induce an animal model of liver disease with secondary splenomegaly to assess the mechanisms underlying the effects of rapamycin and filgrastim when taken separately or in combination on the ...
Shaimaa Abdelrahman +2 more
doaj +1 more source
Elevated barometric pressure suppresses cell proliferation by delaying the G2/M phase and weakening integrin-mediated cell adhesion and actin assembly [PDF]
Archives of Biological Sciences, 2023 Human cells are continuously exposed to various stress factors in their physiological environment. Evidence suggests that certain mechanical stress can affect cell cycle progression and cell proliferation. However, the signaling pathways involved in this
Son Gwang-ic +5 more
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