Results 31 to 40 of about 77,276 (354)
Catastrophic disassembly of actin filaments via Mical-mediated oxidation. [PDF]
, 2017 Actin filament assembly and disassembly are vital for cell functions. MICAL Redox enzymes are important post-translational effectors of actin that stereo-specifically oxidize actin's M44 and M47 residues to induce cellular F-actin disassembly.
Ge, Peng +6 more
core +3 more sources
The unusual dynamics of parasite actin result from isodesmic polymerization [PDF]
, 2013 Previous reports have indicated that parasite actins are short and inherently unstable, despite being required for motility. Here, we re-examine the polymerization properties of actin in Toxoplasma gondii (TgACTI), unexpectedly finding that it exhibits ...
Cooper, John A +6 more
core +2 more sources
Identification of act2, an essential gene in the fission yeast Schizosaccharomyces pombe that encodes a protein related to actin [PDF]
, 1992 Actins are a family of highly conserved proteins that are ubiquitously found among eukaryotic organisms. All actins that have previously been identified, including those of animals, plants, fungi, and protozoa, are 374-376 amino acids long and exhibit at
Lees-Miller, J. P. +2 more
core +1 more source
The Role of non-muscle actin paralogs in cell cycle progression and proliferation
European Journal of Cell Biology, 2023 Uncontrolled cell proliferation leads to several pathologies, including cancer. Thus, this process must be tightly regulated. The cell cycle accounts for cell proliferation, and its progression is coordinated with changes in cell shape, for which ...
Estera Jeruzalska, Antonina J. Mazur
doaj +1 more source
Purification of Human Cytoplasmic Actins From Saccharomyces cerevisiae
Bio-Protocol, 2023 Eukaryotic cells rely on actin to support cellular structure, motility, transport, and a wide variety of other cytoplasmic functions and nuclear activities.
Brian Haarer +2 more
doaj +1 more source
RNA interference in marine and freshwater sponges [PDF]
, 2011 Background: The marine sponge Tethya wilhelma and the freshwater sponge Ephydatia muelleri are emerging model organisms to study evolution, gene regulation, development, and physiology in non-bilaterian animal systems. Thus far, functional methods (i.e.,
Cieniewicz, Brandon +12 more
core +1 more source
Trends in Cell Biology, 1996 The most biologically significant property of actin is its ability to self-associate and form two-stranded polymeric microfilaments. In living cells, these micro filaments form the actin cytoskeleton, essential for maintenance of the shape, passive mechanical properties and active motility of eukaryotic cells. Recently discovered actin-related proteins
R D, Mullins +2 more
openaire +2 more sources
Effect of overexpression of β- and γ-actin isoforms on actin cytoskeleton organization and migration of human colon cancer cells [PDF]
, 2014 Actins are eukaryotic proteins, which are involved in diverse cellular functions including muscle contraction, cell motility, adhesion and maintenance of cell shape.
Agnieszka Popow-Woźniak +4 more
core +1 more source
Actin and Actin-Binding Proteins [PDF]
Cold Spring Harbor Perspectives in Biology, 2016 Organisms from all domains of life depend on filaments of the protein actin to provide structure and to support internal movements. Many eukaryotic cells use forces produced by actin polymerization for their motility, and myosin motor proteins use ATP hydrolysis to produce force on actin filaments.
openaire +2 more sources
Differential Support of Aspergillus fumigatus Morphogenesis by Yeast and Human Actins. [PDF]
PLoS ONE, 2015 The actin cytoskeleton is highly conserved among eukaryotes and is essential for cellular processes regulating growth and differentiation. In fungi, filamentous actin (F-actin) orchestrates hyphal tip structure and extension via organization of exocytic ...
Lawrence L LeClaire, Jarrod R Fortwendel
doaj +1 more source