Results 61 to 70 of about 75,341 (257)
The Actin Cytoskeleton and Actin-Based Motility [PDF]
Cold Spring Harbor Perspectives in Biology, 2018 The actin cytoskeleton-a collection of actin filaments with their accessory and regulatory proteins-is the primary force-generating machinery in the cell. It can produce pushing (protrusive) forces through coordinated polymerization of multiple actin filaments or pulling (contractile) forces through sliding actin filaments along bipolar filaments of ...
openaire +3 more sources
Essential nucleotide- and protein-dependent functions of Actb/β-actin [PDF]
, 2018 The highly similar cytoplasmic β- and γ-actins differ by only four functionally similar amino acids, yet previous in vitro and in vivo data suggest that they support unique functions due to striking phenotypic differences between Actb and Actg1 null ...
Chamberlain, Christopher M. +8 more
core +1 more source
Ring closure in actin polymers [PDF]
Physics Letters A, Vol 381, Issue 11, 18 March 2017, pages
1029-1032, 2017 We present an analysis for the ring closure probability of semiflexible polymers within the pure bend Worm Like Chain (WLC) model. The ring closure probability predicted from our analysis can be tested against fluorescent actin cyclization experiments.We also discuss the effect of ring closure on bend angle fluctuations in actin polymers.
arxiv +1 more source
Orchestrated control of filaggrin-actin scaffolds underpins cornification. [PDF]
, 2018 Epidermal stratification critically depends on keratinocyte differentiation and programmed death by cornification, leading to formation of a protective skin barrier.
Bernardino de la Serna, Jorge +9 more
core +6 more sources
Emerging Functions of Actins and Actin Binding Proteins in Trypanosomatids
Frontiers in Cell and Developmental Biology, 2020 Actin is the major protein constituent of the cytoskeleton that performs wide range of cellular functions. It exists in monomeric and filamentous forms, dynamics of which is regulated by a large repertoire of actin binding proteins. However, not much was
Chhitar M. Gupta +4 more
doaj +1 more source
PLoS Pathogens, 2022 Actin is one of the most conserved and ubiquitous proteins in eukaryotes. Its sequence has been highly conserved for its monomers to self-assemble into filaments that mediate essential cell functions such as trafficking, cell shape and motility.
Michelle Yee +3 more
doaj +1 more source
Shape Changes of Self-Assembled Actin Bilayer Composite Membranes [PDF]
, 1997 We report the self-assembly of thin actin shells beneath the membranes of giant vesicles. Ion-carrier mediated influx of Mg2+ induces actin polymerization in the initially spherical vesicles. Buckling of the vesicles and the formation of blisters after thermally induced bilayer expansion is demonstrated.
arxiv +1 more source
Molecular Model of the Contractile Ring [PDF]
Phys. Rev. Lett. 95, 098102 (2005), 2010 We present a model for the actin contractile ring of adherent animal cells. The model suggests that the actin concentration within the ring and consequently the power that the ring exerts both increase during contraction. We demonstrate the crucial role of actin polymerization and depolymerization throughout cytokinesis, and the dominance of viscous ...
arxiv +1 more source
Involvement of Actin and Actin-Binding Proteins in Carcinogenesis [PDF]
Cells, 2020 The actin cytoskeleton plays a crucial role in many cellular processes while its reorganization is important in maintaining cell homeostasis. However, in the case of cancer cells, actin and ABPs (actin-binding proteins) are involved in all stages of carcinogenesis.
Magdalena Izdebska +3 more
openaire +4 more sources
Structure of isolated Z-disks from honeybee flight muscle [PDF]
, 2017 The Z-disk is a complex structure comprising some 40 proteins that are involved in the transmission of force developed during muscle contraction and in important signalling pathways that govern muscle homeostasis.
Hu, Z, Rusu, M, Taylor, KA, Trinick, J
core +2 more sources