From Cellular Stress to Systemic Adaptation: The Circadian Clock and Stress Response at Cellular and Systemic Levels. [PDF]
Ivankovic I, Ramavath HN, Cao RR.
europepmc +1 more source
Atherosclerotic Cell Fates: A Single-Cell View of ER Stress. [PDF]
Li S, Lu X.
europepmc +1 more source
Ageing stress signalling: metastatic plasticity and metabolic vulnerability in lung cancer. [PDF]
Lee SJ, Bae J, Cheon YJ, Bak SG.
europepmc +1 more source
Short Communication: Activating Transcription Factor 4 (ATF4) Promotes HIV Type 1 Activation
Activating transcription factor 4 (ATF4) is a central factor in the cellular response to multiple stresses, including altered metabolic conditions, anoxia and hypoxia, and redox stress. ATF4 is triggered by endoplasmic reticulum stress and consequent unfolded protein response.
Elisabetta Caselli +2 more
exaly +4 more sources
Functional interaction of protein kinase CK2 and activating transcription factor 4 (ATF4), a key player in the cellular stress response [PDF]
Protein kinase CK2 is a pleiotropic enzyme, which is implicated in the regulation of numerous biological processes. It seems to regulate the various functions by binding to other proteins and by phosphorylation of many different substrates. Here, we identified the activating transcription factor 4 (ATF4), an essential component of the ER stress ...
Claudia Götz +2 more
exaly +4 more sources
Control of Activating Transcription Factor 4 (ATF4) Persistence by Multisite Phosphorylation Impacts Cell Cycle Progression and Neurogenesis* [PDF]
Organogenesis is a highly integrated process with a fundamental requirement for precise cell cycle control. Mechanistically, the cell cycle is composed of transitions and thresholds that are controlled by coordinated post-translational modifications. In this study, we describe a novel mechanism controlling the persistence of the transcription factor ...
Zhigang Xie, Li-Huei Tsai, Xuecai Ge
exaly +7 more sources
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Presence of activating transcription factor 4 (ATF4) in the porcine anterior pituitary
Molecular and Cellular Endocrinology, 1999The two-hybrid system that identifies protein-protein interactions in a yeast expression system was used to investigate porcine anterior pituitary transcription factors. Four cDNA clones of a protein interacting with the leucine zipper domain of porcine cJun were obtained.
Yukio Kato, Susumu Tanaka, Kohei Hosaka
exaly +3 more sources

