Results 201 to 210 of about 16,783,083 (225)

ASK1-Induced FGF21 Synthesis in the Liver Prevents Obesity in Mice. [PDF]

Obesity (Silver Spring)
Goergen A, Challa TD, Villaroel-Vicente C, Borsigova M, van Krieken PP, Wolfrum C, Blüher M, Wueest S, Konrad D.   +8 more
europepmc   +1 more source

Identification of reproductive and molecular biomarkers associated with clinical metritis in dromedary camels (<i>Camelus dromedarius</i>). [PDF]

Front Vet Sci
Alqhtani HA, Elsayed AA, Al-Hazani TMI, Elkhidr RY, Abdelnaby EA, Almubarak AI, Al-Rasheed M, Emam IA, Safhi FA, Zarah RK, Ateya A, Marzok M.   +11 more
europepmc   +1 more source

Effects of the combination of brefeldin A and tunicamycin on endoplasmic reticulum stress and apoptosis in human normal hepatocytes. [PDF]

Curr Res Toxicol
Yang Y, Hou M, Li M, Duan M, Hao Y, Zhao Y, Ji X, Bai J.   +7 more
europepmc   +1 more source

Short Communication: Activating Transcription Factor 4 (ATF4) Promotes HIV Type 1 Activation

AIDS Research and Human Retroviruses, 2012
Activating transcription factor 4 (ATF4) is a central factor in the cellular response to multiple stresses, including altered metabolic conditions, anoxia and hypoxia, and redox stress. ATF4 is triggered by endoplasmic reticulum stress and consequent unfolded protein response.
Elisabetta Caselli, Dario Di Luca, Valentina Gentili   +2 more
exaly   +4 more sources

Functional interaction of protein kinase CK2 and activating transcription factor 4 (ATF4), a key player in the cellular stress response [PDF]

Biochimica Et Biophysica Acta - Molecular Cell Research, 2013
Protein kinase CK2 is a pleiotropic enzyme, which is implicated in the regulation of numerous biological processes. It seems to regulate the various functions by binding to other proteins and by phosphorylation of many different substrates. Here, we identified the activating transcription factor 4 (ATF4), an essential component of the ER stress ...
Claudia Gotz, Mathias Montenarh, Emmanuel Ampofo   +2 more
exaly   +4 more sources

Control of Activating Transcription Factor 4 (ATF4) Persistence by Multisite Phosphorylation Impacts Cell Cycle Progression and Neurogenesis* [PDF]

Journal of Biological Chemistry, 2010
Organogenesis is a highly integrated process with a fundamental requirement for precise cell cycle control. Mechanistically, the cell cycle is composed of transitions and thresholds that are controlled by coordinated post-translational modifications. In this study, we describe a novel mechanism controlling the persistence of the transcription factor ...
Zhigang Xie, Li-Huei Tsai, Xuecai Ge
exaly   +7 more sources

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Presence of activating transcription factor 4 (ATF4) in the porcine anterior pituitary

Molecular and Cellular Endocrinology, 1999
The two-hybrid system that identifies protein-protein interactions in a yeast expression system was used to investigate porcine anterior pituitary transcription factors. Four cDNA clones of a protein interacting with the leucine zipper domain of porcine cJun were obtained.
Kohei Hosaka, K Hosaka, K Tomizawa
exaly   +3 more sources

Activating transcription factor 4

International Journal of Biochemistry and Cell Biology, 2008
Activating transcription factor 4 (ATF4) belongs to the ATF/CREB (activating transcription factor/cyclic AMP response element binding protein) family of basic region-leucine zipper (bZip) transcription factors, which have the consensus binding site cAMP ...
Adrian Harris
exaly   +2 more sources

cAMP-response Element (CRE)-mediated Transcription by Activating Transcription Factor-4 (ATF4) Is Essential for Circadian Expression of the Period2 Gene [PDF]

Journal of Biological Chemistry, 2011
Activating transcription factor (ATF)/cAMP-response element (CRE)-binding (CREB) proteins induce the CRE-mediated gene transcription depending on the cAMP stimulation. cAMP-dependent signaling oscillates in a circadian manner, which in turn also sustains core oscillation machinery of the circadian clock.
Naoki Kusunose, Satoru Koyanagi, Ahmed M Hamdan   +2 more
exaly   +3 more sources

ATF4 (activating transcription factor 4) from grass carp (Ctenopharyngodon idella) modulates the transcription initiation of GRP78 and GRP94 in CIK cells

Fish and Shellfish Immunology, 2014
GRP78 and GRP94, belong to GRP (glucose-regulated protein) family of endoplasmatic reticulum (ER) chaperone superfamily, are essential for cell survival under ER stress. ATF4 is a protective protein which regulates the adaptation of cells to ER stress by modulating the transcription of UPR (Unfolded Protein Response) target genes, including GRP78 and ...
Chuxin Wu, Chengyu Hu, Yichuan Mi
exaly   +4 more sources