Results 211 to 220 of about 16,512,730 (230)

Activating transcription factor 4

open access: yesInternational Journal of Biochemistry and Cell Biology, 2008
Activating transcription factor 4 (ATF4) belongs to the ATF/CREB (activating transcription factor/cyclic AMP response element binding protein) family of basic region-leucine zipper (bZip) transcription factors, which have the consensus binding site cAMP ...
Adrian Harris
exaly   +2 more sources

Identification of Activating Transcription Factor 4 (ATF4) as an Nrf2-interacting Protein [PDF]

open access: yesJournal of Biological Chemistry, 2001
Jawed Alam   +2 more
exaly   +2 more sources

cAMP-response Element (CRE)-mediated Transcription by Activating Transcription Factor-4 (ATF4) Is Essential for Circadian Expression of the Period2 Gene* [PDF]

open access: yesJournal of Biological Chemistry, 2011
Activating transcription factor (ATF)/cAMP-response element (CRE)-binding (CREB) proteins induce the CRE-mediated gene transcription depending on the cAMP stimulation. cAMP-dependent signaling oscillates in a circadian manner, which in turn also sustains core oscillation machinery of the circadian clock.
Naoki Kusunose   +2 more
exaly   +3 more sources

The Murine p8 Gene Promoter Is Activated by Activating Transcription Factor 4 (ATF4) in the Gonadotrope-Derived LβT2 Cell Line

Endocrine, 2006
The factor p8 is a high mobility group (HMG) A family member that is upregulated during the cellular stress response in numerous tissues. Because expression of this protein encourages cellular transformation, our goal is to characterize the mechanism by which the p8 gene is regulated.
Christina M Million, Passe   +2 more
openaire   +2 more sources

Activating Transcription Factor 4 (ATF4) promotes HIV-1 activation

2012
Activating Transcription Factor 4 (ATF4) is a central factor in the cellular response to multiple stresses, including altered metabolic conditions, anoxia and hypoxia, redox stress. ATF4 is triggered by endoplasmic reticulum stress and consequent unfolded protein response.
CASELLI, Elisabetta   +4 more
openaire   +1 more source

Mammary expression of activating transcription factor 4 (ATF4) and tribbles homolog 3 (TRB3) is up‐regulated during CLA‐induced inhibition of milk fat synthesis in the dairy cow

The FASEB Journal, 2008
Trans‐10, cis‐12 conjugated linoleic acid (CLA) originating from ruminal fatty acid biohydrogenation causes milk fat depression (MFD) in dairy cows through a coordinated decrease in mammary expression of lipogenic enzymes. Endoplasmic reticulum (ER) stress is emerging as a causative mechanism of metabolic diseases, with ATF4 and TRB3 providing a link ...
Kevin J Harvatine   +2 more
openaire   +1 more source

Activating Transcription Factor 4 (ATF4)-ATF3-C/EBP Homologous Protein (CHOP) Cascade Shows an Essential Role in the ER Stress-Induced Sensitization of Tetrachlorobenzoquinone-Challenged PC12 Cells to ROS-Mediated Apoptosis via Death Receptor 5 (DR5) Signaling

Chemical Research in Toxicology, 2016
Tetrachlorobenzoquinone (TCBQ) is a downstream metabolite of pentachlorophenol (PCP). Previously, we demonstrated that TCBQ caused cytotoxicity due to mitochondrial-related apoptosis. Here, we confirmed the upregulation of death receptor 5 (DR5) followed by the construction of the death-inducing signaling complex (DISC). We also detected the activation
Zixuan, Liu   +6 more
openaire   +2 more sources

Prognostische Relevanz des activating transcription factor 4 (ATF4) im Ovarialkarzinom

Geburtshilfe und Frauenheilkunde
D. de Beyer   +11 more
openaire   +1 more source

HUMAN HERPESVIRUS 8 UPREGULATES ACTIVATING TRANSCRIPTION FACTOR 4 (ATF4) and REAL TIME PCR TO ASSESS TOTAL BACTERIAL LOAD IN CHRONIC WOUNDS.

2010
I. Human Herpesvirus 8 Upregulates Activator Transcription Factor 4 BACKGROUND: Human herpesvirus 8 (HHV-8) is the primary etiologic agent of Kaposi’s sarcoma, a highly vascularised neoplasm of endothelial origin characterized by inflammation, neoangiogenesis, and by the presence of characteristic spindle cells.
openaire   +1 more source

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