Results 211 to 220 of about 16,783,083 (225)
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Endocrine, 2006
The factor p8 is a high mobility group (HMG) A family member that is upregulated during the cellular stress response in numerous tissues. Because expression of this protein encourages cellular transformation, our goal is to characterize the mechanism by which the p8 gene is regulated.
Christina M Million, Passe +2 more
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The factor p8 is a high mobility group (HMG) A family member that is upregulated during the cellular stress response in numerous tissues. Because expression of this protein encourages cellular transformation, our goal is to characterize the mechanism by which the p8 gene is regulated.
Christina M Million, Passe +2 more
openaire +2 more sources
TPL2 (Therapeutic Targeting Tumor Progression Locus-2)/ATF4 (Activating Transcription Factor-4)/SDF1α (Chemokine Stromal Cell-Derived Factor-α) Axis Suppresses Diabetic Retinopathy [PDF]
Circulation Research, 2017 Rationale: Diabetic retinopathy is characterized by vasopermeability, vascular leakage, inflammation, blood–retinal barrier breakdown, capillary degeneration, and neovascularization. However, the mechanisms underlying the association between diabetes mellitus and progression retinopathy remain ...
Keng-Hung Lin +2 more
exaly +3 more sources
Activating Transcription Factor 4 (ATF4) promotes HIV-1 activation
2012Activating Transcription Factor 4 (ATF4) is a central factor in the cellular response to multiple stresses, including altered metabolic conditions, anoxia and hypoxia, redox stress. ATF4 is triggered by endoplasmic reticulum stress and consequent unfolded protein response.
CASELLI, Elisabetta +4 more
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The FASEB Journal, 2008
Trans‐10, cis‐12 conjugated linoleic acid (CLA) originating from ruminal fatty acid biohydrogenation causes milk fat depression (MFD) in dairy cows through a coordinated decrease in mammary expression of lipogenic enzymes. Endoplasmic reticulum (ER) stress is emerging as a causative mechanism of metabolic diseases, with ATF4 and TRB3 providing a link ...
Kevin J Harvatine +2 more
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Trans‐10, cis‐12 conjugated linoleic acid (CLA) originating from ruminal fatty acid biohydrogenation causes milk fat depression (MFD) in dairy cows through a coordinated decrease in mammary expression of lipogenic enzymes. Endoplasmic reticulum (ER) stress is emerging as a causative mechanism of metabolic diseases, with ATF4 and TRB3 providing a link ...
Kevin J Harvatine +2 more
openaire +1 more source
Chemical Research in Toxicology, 2016
Tetrachlorobenzoquinone (TCBQ) is a downstream metabolite of pentachlorophenol (PCP). Previously, we demonstrated that TCBQ caused cytotoxicity due to mitochondrial-related apoptosis. Here, we confirmed the upregulation of death receptor 5 (DR5) followed by the construction of the death-inducing signaling complex (DISC). We also detected the activation
Zixuan, Liu +6 more
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Tetrachlorobenzoquinone (TCBQ) is a downstream metabolite of pentachlorophenol (PCP). Previously, we demonstrated that TCBQ caused cytotoxicity due to mitochondrial-related apoptosis. Here, we confirmed the upregulation of death receptor 5 (DR5) followed by the construction of the death-inducing signaling complex (DISC). We also detected the activation
Zixuan, Liu +6 more
openaire +2 more sources
Prognostische Relevanz des activating transcription factor 4 (ATF4) im Ovarialkarzinom
Geburtshilfe und FrauenheilkundeD. de Beyer +11 more
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2010
I. Human Herpesvirus 8 Upregulates Activator Transcription Factor 4 BACKGROUND: Human herpesvirus 8 (HHV-8) is the primary etiologic agent of Kaposi’s sarcoma, a highly vascularised neoplasm of endothelial origin characterized by inflammation, neoangiogenesis, and by the presence of characteristic spindle cells.
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I. Human Herpesvirus 8 Upregulates Activator Transcription Factor 4 BACKGROUND: Human herpesvirus 8 (HHV-8) is the primary etiologic agent of Kaposi’s sarcoma, a highly vascularised neoplasm of endothelial origin characterized by inflammation, neoangiogenesis, and by the presence of characteristic spindle cells.
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The gene for the lysosomal protein LAMP3 is a direct target of the transcription factor ATF4
Journal of Biological Chemistry, 2020Jianling Xie +2 more
exaly