Results 201 to 210 of about 3,963,692 (395)

Bacteriophage T4 Genome

Microbiology and Molecular Biology Reviews, 2003
E. S. Miller, E. Kutter, G. Mosig, F. Arisaka, T. Kunisawa, W. Rüger   +5 more
semanticscholar   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

The <i>Caenorhabditis</i> Gli protein TRA-1 makes a transcriptional activator that promotes spermatogenesis. [PDF]

iScience
Shen Y, Lin SY, Guo Y, Imtiaz J, Corley K, Ellis RE.   +5 more
europepmc   +1 more source

Hyperpolarization-activated cyclic nucleotide-gated channels and epilepsy: genetics, circuits, and treatments [PDF]

Ming-Shan Cai, Peng Liao, Zhenliang Hu, Yun Li, Jiaxing Zhao, Liang Jin, Hong-Wei Wang, Yong-Jun Chen   +7 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Enhanced SfaTnpB enables single-base-specific, one-pot nucleic acid detection for high-sensitivity diagnostics. [PDF]

Nucleic Acids Res
Xu B, Li S, Li Y, Zhao S, Li X, Han J, Wu D, Li S, Chen L, Xie S, Han X, Zhao C.   +11 more
europepmc   +1 more source

Plasminogen Activator Inhibitor-1 and Susceptibility to Lung Cancer: A Population Genetics Perspective

, 2014
Ayşegül Bayramoğlu, Hasan Veysi Güneş, Muzaffer Metintaş, İrfan Değirmenci, Halil İbrahim Güler, Cengiz Üstüner, Ahmet Musmul   +6 more
openalex   +2 more sources

Medical genetics: advances in brief: An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia [PDF]

, 1998
D. O Robinson
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

PlantReg 1.1 identifies the mutual arrangement of transcription factor binding sites in the target promoters for the elucidation of molecular mechanisms within regulatory networks. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Lavrekha VV, Omelyanchuk NA, Bogomolov AG, Ryabov YA, Mukebenova PK, Zemlyanskaya EV.   +5 more
europepmc   +1 more source