Results 201 to 210 of about 211,322 (248)
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Review of the Relationship Between the Composition, Strength, and Ultimate Tensile Strain of Engineering Geopolymer Composites. [PDF]
Materials (Basel)Wan X, Guo W, Cong J, Wang C, Han M.
europepmc +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Soluble guanylate cyclase modulators-a novel therapeutic approach for diabetic kidney disease. [PDF]
Ren FailXu Y +8 more
europepmc +1 more source
UQCRC1 deficiency impairs mitophagy via PINK1-dependent mechanisms in Parkinson's disease. [PDF]
NPJ Parkinsons DisLi JL +12 more
europepmc +1 more source
Steric regulation of CRISPR/Cas12a trans-cleavage kinetics via split-activator extensions. [PDF]
Nucleic Acids ResZhang J +12 more
europepmc +1 more source
Exploring natural AMPK activators from bioactive compounds in fenugreek and oyster mushroom for management of type 2 diabetes. [PDF]
Sci RepMazumdar S +5 more
europepmc +1 more source