Results 41 to 50 of about 262,207 (307)

Activation studies of the α- and β-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae with amines and amino acids

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
The α- and β-class carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic bacterium Vibrio cholerae, VchCAα, and VchCAβ, were investigated for their activation with natural and non-natural amino acids and amines.
Andrea Angeli, Sonia Del Prete, Sameh M. Osman, Fatmah A. S. Alasmary, Zeid AlOthman, William A. Donald, Clemente Capasso, Claudiu T. Supuran   +7 more
doaj   +1 more source

Enhancing Citrus Resistance against Huanglongbing using Plant Activators and Copper Acetate [PDF]

Citrus greening (Huanglongbing or HLB) is one of the most destructive citrus diseases. It is caused by the phloem-limited bacterium Candidatus Liberibacter spp. and is difficult to control.
Nasir Ahmed Rajput, Adeel Sultan, Muhammad Atiq   +2 more
core   +2 more sources

Transcriptional regulation: Kamikaze activators [PDF]

, 2000
Transcription factors are often targeted for rapid degradation by the ubiquitin–proteasome system. Recent evidence points to a correlation between the potency and instability of transcriptional activators, suggesting a possible direct role for ubiquitin ...
Thomas, Dominique, Tyers, Mike
core   +1 more source

Inflammasome Activators.

, 2013
Inflammasome Activators.
Aaron F. Hirschfeld (244115), Roger Jen (321977), Stuart E. Turvey (231374), Ashish Sharma (319838), Pascal M. Lavoie (236345), Anthony Tang (321976), Mark A. Chilvers (321978)   +6 more
core   +1 more source

Biofloc derived molecules as bacterial activity activators.

, 2023
Biofloc derived molecules as bacterial activity activators.
Abdallah Ghonimy (15083800), Zhao Chen (92571), Jian Li (41607)   +2 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Development and Experimental Validation of Regularized Machine Learning Models Detecting New, Structurally Distinct Activators of PXR

Cells, 2022
The pregnane X receptor (PXR) regulates the metabolism of many xenobiotic and endobiotic substances. In consequence, PXR decreases the efficacy of many small-molecule drugs and induces drug-drug interactions.
Steffen Hirte, Oliver Burk, Ammar Tahir, Matthias Schwab, Björn Windshügel, Johannes Kirchmair   +5 more
doaj   +1 more source

Robust, synergistic regulation of human gene expression using TALE activators [PDF]

, 2014
Artificial transcription activator-like (TAL) effector-based activators (TALE activators) have broad utility but previous studies suggest that these monomeric proteins often possess low activities.
Linder, Sam, Sander, Jeffry D., Joung, J. Keith, Reyon, Deepak, Fu, Yanfang, Angstman, James, Maeder, Morgan L.   +6 more
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

The Performance of Iron Nanocomposites as Persulfate Activators in Permeable Reactive Barrier Technology for Treatment of Landfill Leachate [PDF]

Avicenna Journal of Environmental Health Engineering
Landfill leachate contains a large organic load and a wide spectrum of pollutants, and it needs appropriate treatment to reduce the severity of these contaminants. Therefore, the present study aimed to remove chemical oxygen demand (COD) and ammonia (NH3
Alaa Mohamad Soubh
doaj   +1 more source