Results 91 to 100 of about 50,825 (299)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Trends in the use of antioxidants in active packaging

, 2012
Introduction: One of the main roles of food packaging is to retard the natural processes that lead to food deterioration and reduction in quality, safety or both.
Sanches-Silva, A., Costa, H.S., Costa, D., Buonocore, G., Albuquerque, T.G.   +4 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Nanocomposites and their application in antimicrobial packaging

Frontiers in Chemistry
The advances in nanocomposites incorporating bioactive substances have the potential to transform the food packaging sector. Different nanofillers have been incorporated into polymeric matrixes to develop nanocomposite materials with improved mechanical,
Adriano Brandelli, Adriano Brandelli
doaj   +1 more source

Active Food Packaging with Antioxidant Properties: Incorporation of Plant Extracts in Polymeric Matrices to Extend Food Shelf-life

, 2014
Comunicação oral proferida a convite.Antioxidants (AOs) play an important role in biological processes because they prevent the effect of reactive oxygen species, protecting against cancer, inflammatory processes, cardiovascular diseases and aging, and ...
Machado, A.V., Sanches-Silva, A., Costa, H.S., Albuquerque, T.G., Ramos, F., Reis, A.R., Castilho, M.C., Carvalho-Costa, D.   +7 more
core  

Novel Bacteriophage-Based Food Packaging: An Innovative Food Safety Approach

, 2023
Research and development on innovative packaging materials have advanced significantly to safeguard packaged food against microbial contamination and oxidation.
Ruchir Priyadarshi, Jong-Whan Rhim, Rajesh V. Wagh   +2 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Nanofillers in Novel Food Packaging Systems and Their Toxicity Issues

Foods
Background: Environmental concerns about petroleum-based plastic packaging materials and the growing demand for food have inspired researchers and the food industry to develop food packaging with better food preservation and biodegradability ...
Xiangyu Zhou, Xiaoyu Zhou, Longli Zhou, Ming Jia, Ying Xiong   +4 more
doaj   +1 more source

Antimicrobial Active Polymers in Food Packaging

, 2015
In the last decades there has been a paradigm shift in food packaging. Nowadays it is not only expected that food packaging act as a protective food barrier; what is expected is that during the period of time that the package is in direct contact with ...
Galotto, María José, Guarda, Abel, López de Dicastillo, Carol, Carol López de Dicastillo, María José Galotto, Abel Guarda   +5 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source