Results 181 to 190 of about 73,976 (284)

Zinc Deficiency Disrupts Germ Cell Nest Breakdown During In Vitro Ovary Culture

Molecular Reproduction and Development, Volume 93, Issue 2, February 2026.
ABSTRACT In mammals, the size of the non‐renewable primordial follicle pool is established before or soon after birth. Primordial follicles, each composed of a single oocyte surrounded by somatic cells, are the only source of gametes during the entire reproductive lifespan of the female.
James M. Hester, Suzanne M. Getman, Melissa E. Pepling, Francisco J. Diaz   +3 more
wiley   +1 more source

Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva.

Journal of Clinical Investigation, 2017
K. Hino, K. Horigome, Megumi Nishio, Shingo Komura, Sanae Nagata, Chengzhu Zhao, Yonghui Jin, K. Kawakami, Yasuhiro Yamada, Akira Ohta, J. Toguchida, M. Ikeya   +11 more
semanticscholar   +1 more source

Frequently Reported Blood Biomarkers in Sarcopenia Clinical Trials: A Systematic Review and Meta‐Analysis

Aging Cell, Volume 25, Issue 2, February 2026.
This systematic review and meta‐analysis identifies blood‐based biomarkers (BBMs) reported in sarcopenia trials, investigating the impact of sarcopenia interventions on BBMs concentrations. Significant heterogeneity was observed in sarcopenia outcomes. Interventions had a limited impact on BBMs, except for IGF‐1, which was significantly impacted by the
Emma Calluy, Yveline Malrechauffé, Emma Boretti, Sophie Van Heden, Dolores Sanchez‐Rodriguez, Yoke Mun Chan, Etienne Cavalier, Aurélie Ladang, Jean‐Yves Reginster, Jonathan Douxfils, Charlotte Beaudart   +10 more
wiley   +1 more source

Pharmacological intervention: Challenges and promising outcomes for fat loss and preservation of lean body mass in the treatment of overweight and type 2 diabetes

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 803-816, February 2026.
Abstract Treatment with GLP‐1 receptor agonists (GLP‐1 RAs) is effective in reducing body weight in individuals with overweight and type 2 diabetes (T2D). However, measurements indicate that a considerable portion of the weight loss derives from fat‐free mass (FFM), including skeletal muscle, which may compromise metabolic health and physical function.
Viktor Aimelet, Jens Juul Holst
wiley   +1 more source

Maternal/zygotic knockout and droplet digital polymerase chain reaction analysis question the role of activin A in preimplantation mouse embryo development†. [PDF]

Biol Reprod
Winek E, Szczepańska K, Wolińska-Nizioł L, Zgódka K, Vaskovicova M, Drutovic D, Suwińska A.   +6 more
europepmc   +1 more source

Hyperglycemia Impairs the Expression of Mediators of Axonal Regeneration During Diabetic Wound Healing in Rats. [PDF]

Biomedicines
Patel J, Ho V, Tran T, Teshome B, Rai V.
europepmc   +1 more source

Sotatercept in Pulmonary Arterial Hypertension: Molecular Mechanisms, Clinical Evidence, and Emerging Role in Reverse Remodelling. [PDF]

Int J Mol Sci
Tilea I, Iancu DG, Fira-Mladinescu O, Bertici N, Varga A.   +4 more
europepmc   +1 more source

Involvement of Activin E depletion in metabolic dysfunction-associated steatohepatitis. [PDF]

Biochem Biophys Rep
Sakaki M, Shikata T, Aoki K, Takano M, Kurisaki A, Funaba M, Hashimoto O.   +6 more
europepmc   +1 more source

Compound KTI-2338 Inhibits ACVR1 Receptor Signaling in Fibrodysplasia Ossificans Progressiva. [PDF]

Pharmaceutics
Rosenberg NM, Zhytnik L, Wisse LE, Botman E, Lachey JL, Eekhoff EMW, Micha D.   +6 more
europepmc   +1 more source

Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines.

Cell Stem Cell, 2011
Steven J. Kattman, A. Witty, Mark Gagliardi, N. Dubois, M. Niapour, A. Hotta, J. Ellis, G. Keller   +7 more
semanticscholar   +1 more source