Results 21 to 30 of about 4,991 (262)

Activins and Activin Receptors in Cell Growth

open access: yesExperimental Biology and Medicine, 1997
Activin and inhibin, members of transforming growth factor-beta (TGFbeta) superfamily, have diverse and widespread effects within living organisms at many stages during growth and development. From the initial isolation of these growth factors based on their effects of FSH secretion, the study of these factors, as well as of the activin-binding protein
S Y, Ying   +5 more
openaire   +2 more sources

Correlations between activins and follistatin. [PDF]

open access: yes, 2016
Correlations between activins and follistatin.
David J. Phillips (2182534)   +7 more
core   +1 more source

A bioinformatic analysis of the inhibin-betaglycan-endoglin/CD105 network reveals prognostic value in multiple solid tumors.

open access: yesPLoS ONE, 2021
Inhibins and activins are dimeric ligands belonging to the TGFβ superfamily with emergent roles in cancer. Inhibins contain an α-subunit (INHA) and a β-subunit (either INHBA or INHBB), while activins are mainly homodimers of either βA (INHBA) or βB ...
Eduardo Listik   +5 more
doaj   +1 more source

Generation of a Specific Activin Antagonist by Modification of the Activin A Propeptide [PDF]

open access: yesEndocrinology, 2011
Elevated activin A levels in inhibin-deficient mice promote the development of gonadal tumors and induce cachexia by reducing muscle, liver, stomach, and fat mass. Because activin A is an important regulator of tissue growth, inhibiting the actions of this TGFβ family ligand may halt or reverse pathology in diseased tissues.
Makanji, Yogeshwar   +5 more
openaire   +4 more sources

Activins as Regulators of Branching Morphogenesis [PDF]

open access: yes, 2001
Development of glandular organs such as the kidney, lung, and prostate involves the process of branching morphogenesis. The developing organ begins as an epithelial bud that invades the surrounding mesenchyme, projecting dividing epithelial cords or ...
Risbridger, Gail P., Ball, Emma M.A.
core   +1 more source

Activins Family [PDF]

open access: yes, 2019
Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release.
nancy murray (6884852)
core   +1 more source

Activin-A: active in inflammation in COPD [PDF]

open access: yesEuropean Respiratory Journal, 2014
Chronic obstructive pulmonary disease (COPD) is characterised by irreversible airflow limitation in which chronic inflammation of the airways plays a major role. The persistent inflammation is triggered by inhaled toxic substances, such as cigarette smoke.
Tania, Navessa P.   +2 more
openaire   +2 more sources

Activins, follistatin and immunoregulation in the epididymis [PDF]

open access: yes, 2019
Background: The interface between the epididymis and the immune system is implicated in many male reproductive pathologies. The resident immune cell populations and immune-environment within the epididymis are significantly different from the testis ...
M. P. Hedger   +3 more
core   +1 more source

Elevated expression of activins promotes muscle wasting and cachexia [PDF]

open access: yes, 2014
Elevated expression of activins promotes muscle wasting and ...
Kelly L Walton (13599535)   +9 more
core   +3 more sources

Dynamics of Transforming Growth Factor (TGF)-β Superfamily Cytokine Induction During HIV-1 Infection Are Distinct From Other Innate Cytokines

open access: yesFrontiers in Immunology, 2020
Human immunodeficiency virus type 1 (HIV-1) infection triggers rapid induction of multiple innate cytokines including type I interferons, which play important roles in viral control and disease pathogenesis.
Matthew Dickinson   +10 more
doaj   +1 more source

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