Substantial Increases Occur in Serum Activins and Follistatin during Lung Transplantation [PDF]
, 2015 SPSS file containing anonymised data set for the publication entitled: "Substantial Increases Occur in Serum Activins and Follistatin during Lung Transplantation".
Robyn E O’Hehir (797208) +7 more
core +1 more source
Soluble activin type IIB receptor improves fracture healing in a closed tibial fracture mouse model. [PDF]
PLoS ONE, 2017 Fractures still present a significant burden to patients due to pain and periods of unproductivity. Numerous growth factors have been identified to regulate bone remodeling.
Tero Puolakkainen +6 more
doaj +1 more source
BMC Biology, 2022 Background Activins and bone morphogenetic proteins (BMPs) play critical, sometimes opposing roles, in multiple physiological and pathological processes and diseases.
Szabina Szófia Szilágyi +4 more
doaj +1 more source
The orphan ligand, activin C, signals through activin receptor-like kinase 7
eLife, 2022 Activin ligands are formed from two disulfide-linked inhibin β (Inhβ) subunit chains. They exist as homodimeric proteins, as in the case of activin A (ActA; InhβA/InhβA) or activin C (ActC; InhβC/InhβC), or as heterodimers, as with activin AC (ActAC ...
Erich J Goebel +8 more
doaj +1 more source
Inactivating the Uninhibited: The Tale of Activins and Inhibins in Pulmonary Arterial Hypertension [PDF]
, 2023 Advances in technology and biomedical knowledge have led to the effective diagnosis and treatment of an increasing number of rare diseases. Pulmonary arterial hypertension (PAH) is a rare disorder of the pulmonary vasculature that is associated with high
Gusty Rizky Teguh Ryanto +3 more
core +1 more source
Structure and activation of pro-activin A
Nature Communications, 2016 Activins are members of the TGF-β family of growth factors that are processed from precursors into the mature proteins. Here, the authors use structural biology and biochemistry to examine the protein domain organisation and gain insights into the ...
Xuelu Wang +2 more
doaj +1 more source
Expression of activin subunits and receptors in the developing human ovary:activin A promotes germ cell survival and proliferation before primordial follicle formation [PDF]
, 2004 The formation of the essential functional unit of the ovary, the primordial follicle, occurs during fetal life in humans. Factors regulating oogonial proliferation and interaction with somatic cells before primordial follicle formation are largely ...
Bayne, R A L +6 more
core +1 more source
Supplementary tables from: Serum activins, follistatins and growth factors in neoplasms of the breast: a case-control study [PDF]
, 2018 Supplementary Tables for: Serum levels of activins, follistatins and growth factors in neoplasms of the breast: A case-control ...
Anastasios Vagionas (5613622) +4 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Differential expression of follistatin and FLRG in human breast proliferative disorders
BMC Cancer, 2009 Background Activins are growth factors acting on cell growth and differentiation. Activins are expressed in high grade breast tumors and they display an antiproliferative effect inducing G0/G1 cell cycle arrest in breast cancer cell lines.
Amaral Vania F +11 more
doaj +1 more source