Results 101 to 110 of about 10,778,046 (183)

Receptor for activated C kinase-1 facilitates protein kinase C-dependent phosphorylation and functional modulation of GABA(A) receptors with the activation of G-protein-coupled receptors [PDF]

, 2002
GABA(A) receptors are the principal sites of fast synaptic inhibition in the brain. These receptors are hetero-pentamers that can be assembled from a number of subunit classes: alpha(1-6), beta(1-3), gamma(1-3), delta(1), epsilon, theta, and pi, but the ...
Trevor G Smart, Brandon, NJ, Jovanovic, JN, Moss, SJ, Stephen J Moss, Smart, TG, Nicholas J Brandon, Jasmina N Jovanovic   +7 more
core  

Functional characterization of Shadoo, a PrP-like protein with neuroprotective activity [PDF]

, 2012
Sakthivelu, Vignesh
core   +1 more source

Protective inherited mutations in activity-dependent neuroprotective protein (ADNP): the good, the bad, and the ugly

Genomic Psychiatry
Activity-dependent neuroprotective protein (ADNP), essential for brain formation/function, reveals multiple cytoplasmic and chromatin interacting sites. Computational modeling, alongside the Vineland Adaptive Behavior Scales, a leading instrument supporting the diagnosis of intellectual/developmental disabilities, now revealed a protective frame shift ...
Illana Gozes, Shula Shazman, Eliezer Giladi, Joseph Levine   +3 more
openaire   +1 more source

Synergism of magnesium- and pyridoxine-dependent proteins in nervous system support: systems biological analysis

Фармакоэкономика
Background. For magnesium–pyridoxine therapy (original drug Magne B6®), the systems-level proteomic synergy of magnesium and pyridoxine-dependent proteins remains to be not sufficiently characterized in the nervous systems of pregnant women and diverse ...
I. Yu. Torshin, O. A. Gromova, M. A. Rogozin, A. N. Gromov   +3 more
doaj   +1 more source

Mecanismos de neuroproteção da guanosina contra a neurotoxicidade induzida por isquemia e dano oxidativo mitocondrial in vitro [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em NeurociênciasA guanosina (GUO) é um modulador endógeno da excitotoxicidade glutamatérgica e promove neuroproteção em modelos de ...
Dal-Cim, Tharine Aparecida
core  

G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton [PDF]

, 2005
G protein-coupled receptor kinase 2 (GRK2) phosphorylates and desensitizes activated G protein-coupled receptors (GPCRs). Here, we identify ezrin as a novel non-GPCR substrate of GRK2. GRK2 phosphorylates glutathione S-transferase (GST)-ezrin, but not an
Pitcher, JA, Cant, SH
core  

Activity-dependent neuroprotective protein (ADNP) is an alcohol-responsive gene and negative regulator of alcohol consumption in female mice. [PDF]

Neuropsychopharmacology, 2019
Ziv Y, Rahamim N, Lezmy N, Even-Chen O, Shaham O, Malishkevich A, Giladi E, Elkon R, Gozes I, Barak S.   +9 more
europepmc   +1 more source

Loss-of-function of activity-dependent neuroprotective protein (ADNP) by a splice-acceptor site mutation causes Helsmoortel-Van der Aa syndrome. [PDF]

Eur J Hum Genet
D'Incal CP, Annear DJ, Elinck E, van der Smagt JJ, Alders M, Dingemans AJM, Mateiu L, de Vries BBA, Vanden Berghe W, Kooy RF.   +9 more
europepmc   +1 more source

Intracellular Crosstalk Between NMDA and Sigma-1 Receptors: A Novel Mechanistic Insight Relevant to Neuropsychiatric Pharmacotherapy. [PDF]

Cells
Lipke K, Piwowar A.
europepmc   +1 more source

Blood-Borne Activity-Dependent Neuroprotective Protein (ADNP) is Correlated with Premorbid Intelligence, Clinical Stage, and Alzheimer's Disease Biomarkers. [PDF]

J Alzheimers Dis, 2016
Malishkevich A, Marshall GA, Schultz AP, Sperling RA, Aharon-Peretz J, Gozes I.   +5 more
europepmc   +1 more source