Lithium for Radiation-Induced Damage in Pediatric Brain Tumors: Preclinical Evidence and Clinical Perspectives. [PDF]
Bardi F +8 more
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Kelulut honey (<i>Heterotrigona itama</i>) as a multi-target neuroprotective strategy against bisphenol A-induced neurotoxicity. [PDF]
Azmi SK, Ali NF, Siran R.
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Naringenin restores neuronal membrane electro-biophysical homeostasis: insights from EIS circuit modeling and molecular dynamics. [PDF]
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Systematic Literature Review of Functional Snacks: Bioactive Properties, Food Technologies, and Consumer Acceptance. [PDF]
Arvilla-Salas L +4 more
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Activity-dependent neuroprotective protein: From gene to drug candidate
Pharmacology & Therapeutics, 2007Activity-dependent neuroprotective protein (ADNP) is essential for brain formation. The gene encoding ADNP is highly conserved and abundantly expressed in the brain. ADNP contains a homeobox profile and a peptide motif providing neuroprotection against a variety of cytotoxic insults.
Illana Gozes
exaly +3 more sources
A Novel VIP Responsive Gene: Activity Dependent Neuroprotective Protein
Annals of the New York Academy of Sciences, 2000Abstract:Activity dependent neuroprotective protein (ADNP, 828 amino acids, pI 5.99) is a glial‐derived protein that contains a femtomolar active neuroprotective peptide, NAPVSIPQ (NAP). VIP induces a two‐ to threefold increase in ADNP mRNA in astrocytes, suggesting that ADNP is a VIP‐responsive gene. ADNP is widely distributed in the mouse hippocampus,
Albert Pinhasov +2 more
exaly +3 more sources
Brain injury-dependent expression of activity-dependent neuroprotective protein
Journal of Molecular Neuroscience, 2004Activity-dependent neuroprotective protein (ADNP), a crucial brain development factor, contains a unique sequence, termed NAPVSIPQ, which protects mice against closed head injury (CHI). The aim of this study was to determine whether CHI affects ADNP mRNA expression in the injured brain hemisphere. Male C57JBL/6J mice were subjected to CHI.
Esther Shohami +2 more
exaly +3 more sources
Recombinant activity-dependent neuroprotective protein protects cells against oxidative stress
Molecular and Cellular Endocrinology, 2006Activity-dependent neuroprotective protein (ADNP) is essential for brain formation. Here, we investigated the potential neuroprotective effects of recombinant ADNP under stress conditions. The human ADNP cDNA was sub-cloned into a vector that contains VP22, a Herpes virus protein that may allow penetration of fused proteins through cellular membranes ...
R A, Steingart, I, Gozes
exaly +3 more sources

