Results 11 to 20 of about 31,404 (216)

ACYCLOVIR CRYSTALLURIA

open access: bronzeThe Pediatric Infectious Disease Journal, 1986
Joseph L. Potter, Carl E. Krill
openalex   +3 more sources

Central Composite Design for Formulation and Optimization of Solid Lipid Nanoparticles to Enhance Oral Bioavailability of Acyclovir

open access: yesMolecules, 2021
Treatment of herpes simplex infection requires high and frequent doses of oral acyclovir to attain its maximum therapeutic effect. The current therapeutic regimen of acyclovir is known to cause unwarranted dose-related adverse effects, including acute ...
Haniza Hassan   +5 more
doaj   +1 more source

Acyclovir induced hypokalemia [PDF]

open access: yesJournal of Clinical Virology, 2013
Intravenous (IV) acyclovir, a mainstay antiviral for herpesviruses, may cause crystalluria and lead to acute kidney injury.1 Acyclovir has been associated with lower levels of potassium in canines but acyclovir induced hypokalemia has been reported only once in humans as part of a large adverse drug reaction monitoring program.2,3 A patient with a ...
Paul E. Drawz   +2 more
openaire   +3 more sources

Vitreous pharmacokinetics and electroretinographic findings after intravitreal injection of acyclovir in rabbits

open access: yesClinics, 2012
OBJECTIVES: Acute retinal necrosis is a rapidly progressive and devastating viral retinitis caused by the herpesvirus family. Systemic acyclovir is the treatment of choice; however, the progression of retinal lesions ceases approximately 2 days after ...
Francisco Max Damico   +8 more
doaj   +1 more source

Two cases of a pharmacokinetic interaction between (val)acyclovir and mycophenolate mofetil

open access: yesClinical Infection in Practice, 2023
Background: Administration of (val)acyclovir in combination with mycophenolate mofetil (MMF) can result in increased acyclovir plasma levels due to competition with acyclovir for renal tubular secretion.
F.A. Berger   +2 more
doaj  

Polymorphs and Hydrates of Acyclovir [PDF]

open access: yesJournal of Pharmaceutical Sciences, 2011
Acyclovir (ACV) has been commonly used as an antiviral for decades. Although the crystal structure of the commercial form, a 3:2 ACV/water solvate, has been known since 1980s, investigation into the structure of anhydrous ACV has been limited. Here, we report the characterization of four anhydrous forms of ACV and a new hydrate in addition to the known
Lutker, Katie M.   +4 more
openaire   +4 more sources

Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2

open access: yesFrontiers in Microbiology, 2019
Omeprazole was shown to improve the anti-cancer effects of the nucleoside analogue 5-fluorouracil. Here, we combined omeprazole with the antiviral nucleoside analogues ribavirin and acyclovir.
Martin Michaelis   +5 more
doaj   +1 more source

Bullous eruptions in a preschool child: A rare adverse effect of acyclovir

open access: yesIndian Journal of Paediatric Dermatology, 2020
Acyclovir in children is usually associated with minimal local adverse effects, with bullous eruptions being extremely rare in occurrence. A 5-year-old boy was admitted to the pediatric intensive care unit as a case of febrile encephalopathy with status ...
Nidhi Garg, K V Vinu Balraam
doaj   +1 more source

Acyclovir-induced neurotoxicity with a positive cerebrospinal fluid varicella zoster PCR result creating a management dilemma: a case report

open access: yesJournal of Medical Case Reports, 2020
Background Varicella zoster virus central nervous system infections can present as aseptic meningitis, encephalitis, myelitis, and vasculopathy.
Kelli M. Robertson   +2 more
doaj   +1 more source

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