Results 11 to 20 of about 31,404 (216)
Joseph L. Potter, Carl E. Krill
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Treatment of herpes simplex infection requires high and frequent doses of oral acyclovir to attain its maximum therapeutic effect. The current therapeutic regimen of acyclovir is known to cause unwarranted dose-related adverse effects, including acute ...
Haniza Hassan+5 more
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Acyclovir induced hypokalemia [PDF]
Intravenous (IV) acyclovir, a mainstay antiviral for herpesviruses, may cause crystalluria and lead to acute kidney injury.1 Acyclovir has been associated with lower levels of potassium in canines but acyclovir induced hypokalemia has been reported only once in humans as part of a large adverse drug reaction monitoring program.2,3 A patient with a ...
Paul E. Drawz+2 more
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OBJECTIVES: Acute retinal necrosis is a rapidly progressive and devastating viral retinitis caused by the herpesvirus family. Systemic acyclovir is the treatment of choice; however, the progression of retinal lesions ceases approximately 2 days after ...
Francisco Max Damico+8 more
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Two cases of a pharmacokinetic interaction between (val)acyclovir and mycophenolate mofetil
Background: Administration of (val)acyclovir in combination with mycophenolate mofetil (MMF) can result in increased acyclovir plasma levels due to competition with acyclovir for renal tubular secretion.
F.A. Berger+2 more
doaj
Polymorphs and Hydrates of Acyclovir [PDF]
Acyclovir (ACV) has been commonly used as an antiviral for decades. Although the crystal structure of the commercial form, a 3:2 ACV/water solvate, has been known since 1980s, investigation into the structure of anhydrous ACV has been limited. Here, we report the characterization of four anhydrous forms of ACV and a new hydrate in addition to the known
Lutker, Katie M.+4 more
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Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2
Omeprazole was shown to improve the anti-cancer effects of the nucleoside analogue 5-fluorouracil. Here, we combined omeprazole with the antiviral nucleoside analogues ribavirin and acyclovir.
Martin Michaelis+5 more
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Bullous eruptions in a preschool child: A rare adverse effect of acyclovir
Acyclovir in children is usually associated with minimal local adverse effects, with bullous eruptions being extremely rare in occurrence. A 5-year-old boy was admitted to the pediatric intensive care unit as a case of febrile encephalopathy with status ...
Nidhi Garg, K V Vinu Balraam
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Background Varicella zoster virus central nervous system infections can present as aseptic meningitis, encephalitis, myelitis, and vasculopathy.
Kelli M. Robertson+2 more
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