Results 21 to 30 of about 27,547 (176)

Acyclovir-Loaded Chitosan Nanospheres from Nano-Emulsion Templating for the Topical Treatment of Herpesviruses Infections

open access: yesPharmaceutics, 2018
Acyclovir is not a good candidate for passive permeation since its polarity and solubility limit is partitioning into the stratum corneum. This work aims to develop a new topical formulation for the acyclovir delivery.
Manuela Donalisio   +6 more
doaj   +1 more source

Bullous eruptions in a preschool child: A rare adverse effect of acyclovir

open access: yesIndian Journal of Paediatric Dermatology, 2020
Acyclovir in children is usually associated with minimal local adverse effects, with bullous eruptions being extremely rare in occurrence. A 5-year-old boy was admitted to the pediatric intensive care unit as a case of febrile encephalopathy with status ...
Nidhi Garg, K V Vinu Balraam
doaj   +1 more source

Effects of Acyclovir on the Cerebellar Cortex of Adult Male Albino Rats And The Protective Effect Of Zinc Sulfate (Histological and Immunohistochemical Study)

open access: yesSVU - International Journal of Medical Sciences
Background: Acyclovir is an antiviral drug. for the treatment of systemic herpes infections and central nervous system infections. Zinc is a vital mineral that found in foods and consumed as a dietary supplement.
Asmaa Sabry Bassit   +2 more
doaj   +1 more source

A Randomized, Double-blind, Placebo-Controlled Study of Efficacy of Oral Acyclovir in the Treatment of Pityriasis Rosea [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Background: Pityriasis rosea is an acute self-limiting skin disorder of unknown aetiology. Recently human herpes virus 6 and 7 has been hypothesized to be the cause of pityriasis rosea. Objective: To determine the efficacy of acyclovir, an anti-viral
Satyaki Ganguly
doaj   +1 more source

Pharmacokinetic and Efficacy Study of Acyclovir Against Cyprinid Herpesvirus 3 in Cyprinus carpio

open access: yesFrontiers in Veterinary Science, 2020
Cyprinid Herpesvirus 3 (CyHV-3), more commonly known as Koi Herpesvirus (KHV), is a re-emergent virus causing acute systemic infection with high mortality rates in koi fish (Cyprinus carpio).
Eva Marie Quijano Cardé   +6 more
doaj   +1 more source

Pseudoboehmite as a drug delivery system for acyclovir

open access: yesScientific Reports, 2021
Herpes simplex virus is among the most prevalent sexually transmitted infections. Acyclovir is a potent, selective inhibitor of herpes viruses and it is indicated for the treatment and management of recurrent cold sores on the lips and face, genital ...
Renato Meneghetti Peres   +9 more
doaj   +1 more source

Therapeutic effects of acyclovir and acyclovir-clobetasol nanofibers vs. cream formulation for recurrent herpes labialis

open access: yesBMC Oral Health
Objectives This study aims to compare the therapeutic effects of acyclovir nanofiber and acyclovir-clobetasol nanofiber formulations with their non-nano formulations (cream formulation) on recurrent labial herpes.
Shahla Mirzaei   +4 more
doaj   +1 more source

Acute renal and neurotoxicity due to weight-based dosing of intravenous acyclovir: How to dose in obese patients?

open access: yesClinical Infection in Practice, 2020
Background: Acyclovir is a hydrophilic drug that is mainly distributed in the lean compartments of the body. Consequently, dosing on total body weight in obese patients may lead to drug overdosing.
Bastiaan TGM Sallevelt   +4 more
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

Synthesis, Characterization and Safety Evaluation of Sericin-Based Hydrogels for Controlled Delivery of Acyclovir

open access: yesPharmaceuticals, 2021
Conventional formulations of antiviral drug acyclovir have various limitations such as low bioavailability. The current study was aimed at developing polymeric matrices for the controlled delivery of acyclovir using sericin as polymer and acrylic acid ...
Moawia M. Al-Tabakha   +6 more
doaj   +1 more source

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