Results 31 to 40 of about 74,334 (181)
Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor [PDF]
, 2010 Background The transition from exponential to stationary phase in Streptomyces coelicolor is accompanied by a major metabolic switch and results in a strong activation of secondary metabolism.
Alam, Mohammad T. +6 more
core +12 more sources
Biomolecules, 2021 The SLC25A20 transporter, also known as carnitine acyl-carnitine carrier (CAC), catalyzes the transport of short, medium and long carbon chain acyl-carnitines across the mitochondrial inner membrane in exchange for carnitine.
Annamaria Tonazzi +4 more
doaj +1 more source
Crystal structure of Pseudomonas aeruginosa FabB C161A, a template for structure-based design for new antibiotics [PDF]
, 2021 Background: FabB (3-oxoacyl-[acyl-carrier-protein] synthase 1) is part of the fatty acid synthesis II pathway found in bacteria and a potential target for antibiotics.
Brenk, Ruth +2 more
core +1 more source
The Distinctive Regulatory Mechanisms of Bacterial Acetyl-CoA Carboxylase [PDF]
, 2018 Metabolic Regulation is a complex system used to control cellular metabolism in response to conditions in the cell’s environment. For most enzymes, the cell can rely upon a minimal amount of regulation; however, critical enzymes, such as acetyl-CoA ...
Evans, Alexandra Leigh
core +2 more sources
NMR Studies of Escherichia Coli Acyl Carrier Protein: Dynamic and Structural Differences of the Apo- and Holo-forms [PDF]
, 2006 Two indicators of conformational variability of Escherichia coli acyl carrier protein (ACP) have been investigated, namely backbone dynamics and chemical shift variations of ACP.
Eletr, Ziad +2 more
core +2 more sources
Microbiology Spectrum, 2022 Phosphopantetheinyl transferases (PPTases) play important roles in activating apo-acyl carrier proteins (apo-ACPs) and apo-peptidyl carrier proteins (apo-PCPs) in both primary and secondary metabolism. PPTases catalyze the posttranslational modifications
Songya Zhang +7 more
doaj +1 more source
Identifying Novel Inhibitors of RpFabG in Typhus-inducing Rickettsia prowazekii [PDF]
, 2019 Epidemic typhus is a rickettsial disease that is contracted via ticks and lice found on the flying squirrel. The disease is caused by Rickettsia prowazekii, an intracellular, gram-negative coccobacillus.
Panatpur, Aparna
core +1 more source
High temperature during soybean seed development differentially alters lipid and protein metabolism
Plant Production Science, 2020 High temperatures during seed development can affect the seed yield and quality in many crops. Here, we analyzed how high temperature alters the main seed storage compounds (lipid and protein) in soybean. At five days after R5 stage (initial seed filling
Andressa C. S. Nakagawa +7 more
doaj +1 more source
Molecular Plant-Microbe Interactions, 2001 The acyl carrier protein NodF is required for the synthesis of unusual polyunsaturated fatty acids that confer specificity to lipochitin oligosaccharide nodulation (Nod) factors of Rhizobium leguminosarum. In this study, homogeneous NodF protein was used
Isabel M. López-Lara, Otto Geiger
doaj +1 more source
Antibiotics, 2022 Type II fatty acid synthases are promising drug targets against major bacterial pathogens. Platensimycin (PTM) is a potent inhibitor against β-ketoacyl-[acyl carrier protein] synthase II (FabF) and β-ketoacyl-[acyl carrier protein] synthase I (FabB ...
Youchao Deng +7 more
doaj +1 more source