Versatility of Acyl-Acyl Carrier Protein Synthetases
Chemistry & Biology, 2014 The acyl carrier protein (ACP) requires posttranslational modification with a 4'-phosphopantetheine arm for activity, and this thiol-terminated modification carries cargo between enzymes in ACP-dependent metabolic pathways. We show that acyl-ACP synthetases (AasSs) from different organisms are able to load even, odd, and unnatural fatty acids onto E ...
Kara Finzel +2 more
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Cycvalone in the synthesis of nitrogen-, oxygen-containing heterocycles [PDF]
Известия Саратовского университета. Новая серия: Серия Химия. Биология. Экология, 2023 Cycvalone is an analogue of curcumin (EE conformation), exhibits a wide range of biological activity (antioxidant, hepatoprotective, membrane stabilizing, anti-ulcer) and is used in medical practice as a choleretic.
Rogov, Danila A. +1 more
doaj +1 more source
A Receptor Component of the Chloroplast Protein Translocation Machinery [PDF]
, 1994 The chloroplast outer envelope protein OEP86 functions as a receptor in precursor protein translocation into chloroplasts. Sequence analysis suggests that the precursor of OEP86 is directed to the chloroplast outer envelope by a cleavable, negatively ...
Heemeyer, Frank +4 more
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Synthesis of 2-Acylphenol and Flavene Derivatives from the Ruthenium-Catalyzed Oxidative C-H Acylation of Phenols with Aldehydes [PDF]
, 2015 The cationic ruthenium hydride complex [(C6H6)(PCy3)(CO)RuH]+BF4− has been found to be an effective catalyst for the oxidative C–H coupling reaction of phenols with aldehydes to give 2-acylphenol compounds.
Aponick +47 more
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A broad inhibitor of acyl-acyl carrier protein synthetases
Biochemistry and Biophysics Reports, 2023 The acyl-acyl carrier protein synthetase enzyme enables some bacteria to scavenge free fatty acids from the environment for direct use in lipids. This fatty acid recycling pathway can help pathogens circumvent fatty acid synthase (FAS) inhibition with established antibiotics and those in clinical development.
Magdalena Todorinova +2 more
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Acylated and non-acylated anthocyanins as antibacterial and antibiofilm agents
Discover Food, 2023 AbstractNatural products have served as an essential source of medicinal compounds in drug discovery, with their high abundance in nature and structural complexity being beneficial for various biological activities. Anthocyanins are a natural food colourant that belongs to the flavonoid group of compounds responsible for the colour of various fruits ...
Jeyaraj, Ethel Jeyaseela +3 more
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Molbank, 2022 The hetero-Diels–Alder reaction is the main synthetic tool for obtaining pharmacological agents with a thiopyrano[2,3-d]thiazole motif. In the present work, an efficient method for the synthesis of pyrazoline-containing thiopyrano[2,3-d]thiazole is ...
Ihor Yushyn +3 more
doaj +1 more source
Oxidative acylation of sulfoximines with methylarenes as an acyl donor [PDF]
RSC Advances, 2015 An efficient direct oxidative acylation of sulfoximines with methylarenes as an acyl donor was finally achieved.
Junfeng Zhao +4 more
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Correction: de Gonzalo, G. Lipase Catalysed Kinetic Resolution of Racemic 1,2-Diols Containing a Chiral Quaternary Center. Molecules 2018, 23, 1585 [PDF]
, 2018 n/
Gonzalo Calvo, Gonzalo de
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Chemical Modification of Pectin and Polygalacturonic Acid: A Critical Review
BioResources, 2021 Pectin, as a sustainable biopolymer with its two complementary functionalities (carboxyl and hydroxyl moieties) imparted in the α-1,4-galacturonic acid repeating unit, has gained increasing attention in the last few years.
Hendryk Würfel +3 more
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