Results 61 to 70 of about 89,225 (346)

N-Acylation of Oxazolidinones via Aerobic Oxidative NHC Catalysis [PDF]

, 2018
In the ongoing quest to find alternatives to atom un-economical and forcing conditions in acylation reactions, aerobic oxidative NHC catalysis has emerged as a method to convert aldehydes to potent acylating reagents.
Henrik Sundén (1399444), Anton, Axelsson, Sund\ue9n, Henrik, Linda, Ta, Axelsson, Anton,, Linda Ta (257721), Henrik Sundén (5214749), Anton Axelsson, Anton Axelsson (5215523), Henrik, Sundén, Ta, Linda,, Linda Ta, Sundén, Henrik,, Ta, Linda, Axelsson, Anton, Henrik Sundén   +15 more
core   +1 more source

Biocatalytic approach to the chemoselective acylation of sesquiterpene lactones from chicory: a pathway to novel ester derivatives [PDF]

, 2023
In this study, we explore the use of the immobilized lipase Novozym 435 in the selective acylation of chicory sesquiterpene lactones (STLs) - lactucin (Lc), 11β,13-dihydrolactucin (DHLc), lactucopicrin (Lp), and 11β,13-dihydrolactucopicrin (DHLp) - using
Rénato, Froidevaux, Jean-Louis, Hilbert, Catherine, Humeau, Juan, RODRIGUEZ MOSHEIM, Egon, Heuson, Philippe, Hance, Nicolas, Willand, Francesca, Ruggieri   +7 more
core   +1 more source

Assaying protein palmitoylation in plants

Plant Methods, 2008
Background Protein S-acylation (also known as palmitoylation) is the reversible post-translational addition of acyl lipids to cysteine residues in proteins through a thioester bond. It allows strong association with membranes.
Taylor Laura, Hemsley Piers A, Grierson Claire S   +2 more
doaj   +1 more source

Histone acylation marks respond to metabolic perturbations and enable cellular adaptation

Experimental and Molecular Medicine, 2020
Acetylation is the most studied histone acyl modification and has been recognized as a fundamental player in metabolic gene regulation, whereas other short-chain acyl modifications have only been recently identified, and little is known about their ...
Chanhee Jo, Seokjae Park, Sungjoon Oh, Jinmi Choi, Eun-Kyoung Kim, H. Youn, E. Cho   +6 more
semanticscholar   +1 more source

Chemoenzymatic Synthesis of Well‐Defined α(2,8)‐ and α(2,9)‐Linked Oligosialosides

Angewandte Chemie, EarlyView.
Well‐defined α(2,8)‐ and α(2,9)‐linked oligosialic acids of different lengths can be prepared by employing recombinant bacterial polysialyltransferases in combination with chemically modified CMP‐Neu5Ac derivatives. After transfer, a sialoside is formed bearing an artificial entity, which blocks further glycosylation.
Jelle A. Fok, Keshav Kishor, Mehman I. Bunyatov, Gerlof P. Bosman, Geert‐Jan Boons   +4 more
wiley   +2 more sources

Chiral isothiourea-catalyzed kinetic resolution of 4-hydroxy[2.2]paracyclophane

Beilstein Journal of Organic Chemistry, 2021
We herein report a method for the kinetic resolution of racemic 4-hydroxy[2.2]paracyclophane by means of a chiral isothiourea-catalyzed acylation with isobutyric anhydride.
David Weinzierl, Mario Waser
doaj   +1 more source

Palmitoylation as a Key Regulator of Ras Localization and Function

Frontiers in Molecular Biosciences, 2021
Ras proteins require membrane association for proper function. This process is tightly regulated by reversible palmitoylation that controls not only the distribution over different subcellular compartments but also Ras compartmentalization within ...
Carla Busquets-Hernández, Gemma Triola
doaj   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Rediscovering the double Friedel-Crafts acylation : an expedient entry to phenanthrene-9,10-diones [PDF]

, 2013
The double Friedel–Crafts acylation of readily accessible biaryls with oxalyl chloride delivers the respective phenanthrene-9,10-diones, providing an alternative to the traditional methods, which require harsh oxidizing conditions and multistep sequences.
Müller, Sebastian, Bräse, Stefan, Gradl, Dietmar, Masters, Kye-Simeon, Crosta, Nicoletta   +4 more
core   +1 more source

A Lipid‐Conjugation Strategy for Intracellular Reactive Oxygen Species Control in Hepatic Cells

Angewandte Chemie, EarlyView.
A lipid conjugation strategy anchors a manganese Salen complex within phospholipid membranes, yielding stable, catalytically active liposomes. These lipid–metal assemblies efficiently degrade reactive oxygen species (ROS) and enable intracellular redox control in steatotic HepaRG cells, offering a precise route to biomimetic antioxidant design ...
Olav Vestrheim, Huichao Zhao, Anders Bodholt Nielsen, Nino Wili, Niels Chr. Nielsen, Joseph A. Lyons, Rajeshwar Prosad Mookerjee, Brigitte Städler   +7 more
wiley   +2 more sources