Poly (glycerol adipate) (PGA), an enzymatically synthesized functionalizable polyester and versatile drug delivery carrier : A literature update [PDF]
, 2019 The enzymatically synthesized poly (glycerol adipate) (PGA) has demonstrated all the desirable key properties required from a performing biomaterial to be considered a versatile "polymeric-tool" in the broad field of drug delivery.
Garnett, Martin C. +3 more
core +3 more sources
T cell receptor–dependent S-acylation of ZAP-70 controls activation of T cells
bioRxiv, 2020 ZAP-70 is a cytoplasmic tyrosine kinase essential for T cell-mediated immune responses. Upon engagement of the T cell receptor, ZAP-70 is quickly recruited to the specialized plasma membrane domains, becomes activated and released to phosphorylate its ...
R. Tewari +3 more
semanticscholar +1 more source
Detection of S-Acylated CD95 by Acyl-Biotin Exchange [PDF]
, 2017 S-acylation is the covalent addition of a fatty acid, most generally palmitate onto cysteine residues of proteins through a labile thioester linkage. The death receptor CD95 is S-palmitoylated and this post-translational modification plays a crucial role on CD95 organization in cellular membranes and thus on CD95-mediated signaling.
Rossin, Aurélie, Hueber, Anne-Odile
openaire +2 more sources
Triacylglycerol synthesis in rat adipose tissue : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]
, 1983 Adipose tissue consists of two types of cell; the adipocyte and the non-adipocyte {Rodbell, 1964). The adipocyte is unique amongst mammalian cell types in that one class of component {TG) comprises up to 80% of its weight.
Wilson, Russell Douglas
core
S-acylation in plants: an expanding field.
Biochemical Society Transactions, 2020 S-acylation is a common yet poorly understood fatty acid-based post-translational modification of proteins in all eukaryotes, including plants. While exact roles for S-acylation in protein function are largely unknown the reversibility of S-acylation ...
P. Hemsley
semanticscholar +1 more source
The low intestinal and hepatic toxicity of hydrolyzed fumonisin B1 correlates with its inability to alter the metabolism of sphingolipids [PDF]
, 2012 Fumonisins are mycotoxins frequently found as natural contaminants in maize, where they are produced by the plant pathogen Fusarium verticillioides. They are toxic to animals and exert their effects through mechanisms involving disruption of sphingolipid
Bracarense, Ana-Paula +8 more
core +3 more sources
Isolation, X-ray Structures, and Electronic Spectra of Reactive Intermediates in Friedel−Crafts Acylations [PDF]
, 2005 Reactive intermediates in the Friedel−Crafts acylation of aromatic donors are scrutinized upon their successful isolation and X-ray crystallography at very low temperatures.
Davlieva, M. G. +3 more
core +1 more source
A gene-derived SNP-based high resolution linkage map of carrot including the location of QTL conditioning root and leaf anthocyanin pigmentation [PDF]
, 2014 Purple carrots accumulate large quantities of anthocyanins in their roots and leaves. These flavonoid pigments possess antioxidant activity and are implicated in providing health benefits.
Cavagnaro, Pablo Federico +6 more
core +2 more sources
Juxta-membrane S-acylation of plant receptor-like kinases is likely fortuitous and does not necessarily impact upon function [PDF]
, 2019 This work was funded by UK Biotechnology and Biological Sciences Research Council Grants BB/M024911/1 and BB/M010996/1 to P.A.H.S-acylation is a common post-translational modification of membrane protein cysteine residues with many regulatory roles.
Hemsley, Piers +5 more
core +4 more sources
Interdisciplinary Research-Based Learning in Organic Chemistry and Microbiology Laboratories: Synthesis and Biological Testing of Novel Penicillin Derivatives [PDF]
, 2015 Interests in the mechanism that penicillin bestows on its target protein has driven the curiosity of its binding specificity towards the methicillin resistant strain of Staphylococcus areus, and its expression of a unique penicillin binding protein that ...
Rehberger, Kyle R.
core +1 more source