Results 71 to 80 of about 60,893 (292)

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

open access: yesAdvanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang   +15 more
wiley   +1 more source

Effect of Acylation of Flavones with Hydroxycinnamic Acids on their Spectral Characteristics

open access: yesNatural Product Communications, 2007
The absorption spectra of twenty-one flavones including glycosides of apigenin, luteolin, chrysoeriol and tricin, nonacylated or acylated with coumaric, ferulic or sinapic acids, were examined to document the influence of acylation on their spectral ...
Anna Stochmal, Wieslaw Oleszek
doaj   +1 more source

Unexpected reversal of the regioselectivity in Thermomyces lanuginosus lipase-catalyzed acylation of floxuridine

open access: yes, 2009
Unexpected inversion of the 3':5'-regioselectivity was observed in the enzymatic methacryloylation, crotonylation and cinnamoylation of floxuridine (1.5:1, 2.3:1 and 4.4:1, respectively), where Thermomyces lanuginosus lipase preferentially catalyzed the ...
Li, Ning   +4 more
core   +1 more source

Oleate activates PLD2 lipase and GEF activity by modulating membrane microdomain dynamics via S-acylation

open access: yesJournal of Lipid Research
Phospholipase D2 (PLD2) plays critical roles in cellular signaling, membrane dynamics, and cancer progression. Oleate (OA) has been shown to activate PLD2 and promote triple-negative breast cancer (TNBC) cell migration, but the underlying molecular ...
Zhiqiang Guo   +2 more
doaj   +1 more source

O-acylation of chitosan nanofibers by short-chain and long-chain fatty acids

open access: yes, 2017
Chitosan nanofibers (CSNFs) have potential applications in biomaterials, oil recovery and food packaging, but their instability in moist environment has limited their full utilization. Here we report that CSNFs can be O-acylated in a post-electrospinning
Zhen Zhang   +19 more
core   +1 more source

Anthocyanin Profiles in Flowers of Grape Hyacinth

open access: yesMolecules, 2017
Grape hyacinth (Muscari spp.) is a popular ornamental bulbous perennial famous for its blue flowers. To understand the chemical basis of the rich blue colors in this plant, anthocyanin profiles of six blue flowering grape hyacinths as well as one pink ...
Qian Lou, Lin Wang, Hongli Liu, Yali Liu
doaj   +1 more source

Synthesis of 5-acylindoles via regioselective acylation of 3-trifluoroacetylindole

open access: yes, 2003
5-Acylindoles were synthesized by regioselective acylation of 3-trifluoroacetylindole with acyl chloride under the catalysis of Lewis acids, followed by hydrolysis of trifluoroacetyl and decarboxylation.
Li, J   +4 more
core  

Processes and therapeutic perspectives of acylation modifications of lysine and cysteine in tumors

open access: yesCell Communication and Signaling
Acylation modification plays a crucial role in tumor progression through altering protein homeostasis and localization. However, a comprehensive summary of these processes is lacking.
Jialin Jiang   +15 more
doaj   +1 more source

Efficient Chitin Derivatization Methods Using Ionic Liquids and Deep Eutectic Solvents

open access: yesMacromol
Ionic liquids (ILs) and deep eutectic solvents (DESs) have emerged as effective solvents for poorly soluble materials such as natural polysaccharides, including chitin. This review describes recently developed efficient chitin derivatization methods that
Masayasu Totani, Jun-ichi Kadokawa
doaj   +1 more source

Development of cation-directed acylation reactions [PDF]

open access: yes, 2018
This thesis describes work conducted towards the enantioselective acylation of ketones using phase-transfer catalysis. Chapter 1 introduces the field of ketone acylation, with a focus on catalytic methods accompanied by the generation of axes, planes ...
Rahemtulla, Benjamin F.
core   +1 more source

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