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Acyltransferases in Protease’s Clothing [PDF]
One of the most intriguing questions in plant secondary metabolism concerns the evolution of the genes required for the rapid diversification of plant chemistry. In particular, the mechanisms are beginning to be understood by which evolution recruits primary and intermediary metabolism genes ...
openaire +3 more sources
In rhizobium strains, the lipid A is modified by the addition of a very long-chain fatty acid (VLCFA) shown to play an important role in rigidification of the outer membrane, thereby facilitating their dual life cycle, outside and inside the plant.
Nicolas Busset+10 more
doaj +1 more source
Fatty acyl recognition and transfer by an integral membrane S-acyltransferase
Fattening up proteins Many eukaryotic proteins are modified by the attachment of lipids, and these modifications can alter how proteins interact with cellular membranes. Rana et al.
M. Rana+5 more
semanticscholar +1 more source
The role of PAF in immunopathology: From immediate hypersensitivity reactions to fungal defense
Abstract Platelet‐activating factor (PAF, 1‐alkyl‐2‐acetyl‐sn‐glycero‐3‐phosphorylcholine) was discovered when the mechanisms involved in the deposition of immune complex in tissues were being scrutinized in the experimental model of rabbit serum sickness.
Mariano Sánchez Crespo+2 more
wiley +1 more source
Lipid metabolism in pancreatic cancer: emerging roles and potential targets
Abstract Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently <9%. Patients typically present with advanced disease due to vague symptoms or lack of screening for early cancer detection.
Xinpeng Yin+6 more
wiley +1 more source
Protein acylation is critical for many cellular functions across all domains of life. In bacteria, lipoproteins have important roles in virulence and are targets for the development of antimicrobials and vaccines. Bacterial lipoproteins are secreted from
Christopher Icke+7 more
doaj +1 more source
Legionella pneumophila genes encoding LapA, LapB, and PlaC were identified as the most highly upregulated type II secretion (T2S) genes during infection of Acanthamoeba castellanii, although these genes had been considered dispensable on the basis of the
Richard C. White+6 more
doaj +1 more source
A cyanobacterium, Synechocystis sp. PCC 6803, contains a lipid with triacylglycerol-like TLC mobility but its identity and physiological roles remain unknown. Here, on ESI-positive LC-MS2 analysis, it is shown that the triacylglycerol-like lipid (lipid X)
Mimari Kondo+6 more
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The aerial organs of most terrestrial plants are covered by a hydrophobic protective cuticle. The main constituent of the cuticle is the lipid polyester cutin, which is composed of aliphatic and aromatic domains.
Ping-Ping Wang+3 more
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Capsaicin, produced by diverse Capsicum species, is among the world’s most popular spices and of considerable pharmaceutical relevance. Although the capsaicinoid biosynthetic pathway has been investigated for decades, several biosynthetic steps have ...
Raika Milde+6 more
doaj +1 more source