Results 31 to 40 of about 86,883 (336)

Functional Characterization of a Hydroxyacid/Alcohol Hydroxycinnamoyl Transferase Produced by the Liverwort Marchantia emarginata

Molecules, 2017
The aerial organs of most terrestrial plants are covered by a hydrophobic protective cuticle. The main constituent of the cuticle is the lipid polyester cutin, which is composed of aliphatic and aromatic domains.
Ping-Ping Wang, Hui Liu, Shuai Gao, Ai-Xia Cheng   +3 more
doaj   +1 more source

In Vitro Analysis of Hedgehog Acyltransferase and Porcupine Fatty Acyltransferase Activities [PDF]

, 2019
Hedgehog and Wnt proteins are modified by covalent attachment of the fatty acids palmitate and palmitoleate, respectively. These lipid modifications are essential for Hedgehog and Wnt protein signaling activities and are catalyzed by related, but distinct fatty acyltransferases: Hedgehog acyltransferase (Hedgehog) and Porcupine (Wnt).
James J. Asciolla, James J. Asciolla, Kalpana Rajanala, Marilyn D. Resh, Marilyn D. Resh   +4 more
openaire   +2 more sources

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

Hepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou, Kaiwei Jia, Suyuan Wang, Zhenyang Li, Yunhui Li, Shan Lu, Yingyun Yang, Liyuan Zhang, Mu Wang, Yue Dong, Luxin Zhang, Wannian Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou   +15 more
wiley   +1 more source

Molecular and Genetic Regulation of Sensory Quality of Climacteric Fruit [PDF]

, 2004
The sensory quality of fruit has become a major criterion in making the purchasing decision by consumers. Breeding programs have mainly been directed, from the post-harvest stand point, towards improving shelf-life.
A. Latché, D. Manriquez, F.B. Flores, I. El-Sharkawy, J.C. Pech   +4 more
core   +1 more source

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez   +22 more
wiley   +1 more source

Evolutionary Developments in Plant Specialized Metabolism, Exemplified by Two Transferase Families

Frontiers in Plant Science, 2019
Plant specialized metabolism emerged from the land colonization by ancient plants, becoming diversified along with plant evolution. To date, more than 1 million metabolites have been predicted to exist in the plant kingdom, and their metabolic processes ...
Hiroaki Kusano, Hao Li, Hiroshi Minami, Yoshihiro Kato, Homare Tabata, Kazufumi Yazaki   +5 more
doaj   +1 more source

The cholesterol-raising diterpenes from coffee beans increase serum lipid transfer protein activity levels in humans [PDF]

, 1997
Cafestol and kahweol–diterpenes present in unfiltered coffee— strongly raise serum VLDL and LDL cholesterol and slightly reduce HDL cholesterol in humans. The mechanism of action is unknown.
Gent, T. van, Jong-Caesar, R. de, Katan, M.B., Roos, B. de, Scheek, L. M., Tol, A. van, Urgert, R.   +6 more
core   +3 more sources

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

Acylation of monolysocardiolipin in rat heart

Journal of Lipid Research, 1999
Cardiolipin is a major mitochondrial membrane glycerophospholipid in the mammalian heart. In this study, the ability of the isolated intact rat heart to remodel cardiolipin and the mitochondrial enzyme activities that reacylate monolysocardiolipin to ...
Brian J. Ma, William A. Taylor, Vernon W. Dolinsky, Grant M. Hatch   +3 more
doaj   +1 more source

Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. [PDF]

, 2010
Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here we identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a key host factor for HCV infection.
Carpentier, Arnaud, Farese, Robert V, Harris, Charles, Herker, Eva, Hernandez, Céline, Kaehlcke, Katrin, Ott, Melanie, Rosenberg, Arielle R   +7 more
core   +1 more source