Results 231 to 240 of about 2,414,633 (297)

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

The FEBS Journal, EarlyView.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh, Ivan Gallotta, Bolanle F. Olabiyi, Yoon Hee Choi, Sarah Inglesfield, Janet R. Kumita, Collin Y. Ewald, Della C. David   +7 more
wiley   +1 more source

From peripheral blood neutrophils and monocytes to microglia in the brain: Converging evidence for innate immune activation in schizophrenia and major depression. [PDF]

Dusunen Adam
Dudeck L, Guest PC, Steiner J.
europepmc   +1 more source

Short‐term survival of mallards following external transmitter attachment

Ibis, EarlyView.
Capturing birds for external transmitter attachment allows researchers to collect abundant movement and behavioural data across spatial and temporal gradients but can expose birds to additional stress due to prolonged handling, sometimes leading to mortality.
Cassidy L. Waldrep, Madeline A. Ward, John M. Coluccy, Joshua C. Stiller, Jacob N. Straub, Nathaniel R. Huck, Ted. S Barney, Abigail C. Butler, Austin H. Damminger, Shawn W. Meyer, Theodore C. Nichols, Daria J. Sparks, Mathieu Tétreault, Mitch D. Weegman   +13 more
wiley   +1 more source

MMR Vaccination and Hen's Egg Allergy: Bridging the Gap Between Evidence and Clinical Practice. [PDF]

Vaccines (Basel)
Balas WM, Kaczor M, Strzelecka J, Sybilski AJ.   +3 more
europepmc   +1 more source

Integrative transcriptomic and machine learning approaches reveal candidate genes for silk and venom production in Bibionomorpha (Diptera)

Insect Molecular Biology, EarlyView.
Multi‐species transcriptomics and deep learning identified candidate genes associated with silk and venom production in Bibionomorpha. Venom‐associated genes were enriched in proteases, inhibitors and pore‐forming proteins, whereas silk‐related genes showed chitin‐binding and peritrophin domains. Integrating co‐expression networks, machine learning and
Daniel Kenji Matuo, João Alfredo Teodoro, Danilo T. Amaral   +2 more
wiley   +1 more source

Lipids challenge ligands to control receptors. [PDF]

Elife
Wollman AJM.
europepmc   +1 more source

Irradiation‐Induced CD62L Shedding in Human Plasmacytoid Dendritic Cells Depends on ADAM17 and p38 MAPK

Immunology, EarlyView.
Human plasmacytoid dendritic cell‐based vaccines efficiently migrate from blood to lymph nodes and prime naive T cells in humanised mice. Irradiation‐induced CD62L shedding, mediated by p38 MAP kinase and ADAM17, is involved in the regulation of PDC migration to secondary lymphoid organs in this model.
Estelle Leplus, Jamila Kacher, Dalil Hannani, Guillaume Vayssiere, Jean‐Paul Molens, Karine Laulanier, Dan Georgess, Véronique Josserand, Philippe Saas, Séverine Planel, Laurence Chaperot, Joel Plumas   +11 more
wiley   +1 more source

Urinary Proteomics Identifies ADAMDEC1 as a Non-invasive Biomarker of Unstable Carotid Atherosclerotic Plaques. [PDF]

Mol Cell Proteomics
Yu T, Qin Q, Zhou Y, Zhang M, Zhang Q, Yang S, Ma Y, Xu B, Liu R.   +8 more
europepmc   +1 more source

Melanoma and Other Melanistic Lesions in Brown Bullhead Ameiurus nebulosus From Waterbodies in the Northeastern United States and Canada: Identification of Risk Factors

Journal of Fish Diseases, EarlyView.
ABSTRACT Melanistic lesions, including non‐raised black areas due to proliferations of melanocytes and melanomacrophages in the dermis and epidermis, as well as raised black areas consistent with melanoma, are described in brown bullhead (BBH) Ameiurus nebulosus from three water bodies in the northeastern United States and Quebec, Canada.
Vicki S. Blazer, Peter Emerson, Matthew Bodnar, Thomas Jones, David R. Russell, Matthew Pehrson, Cheyenne R. Smith, Danielle Cleveland, Mark J. Henderson, Patricia M. Mazik   +9 more
wiley   +1 more source

Naturally occurring ACE2 stalk variants are differentially released from the cell. [PDF]

Sci Rep
Wiersch F, Lux C, Vanderliek-Kox J, Schun K, Ludwig A, Düsterhöft S.   +5 more
europepmc   +1 more source