Results 91 to 100 of about 380 (133)

The role of ADAMTS-1, -4 and -5 in multiple sclerosis. [PDF]

open access: yes
ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-1, -4 and -5 are secreted enzymes which are members of the glutamyl endopeptidases (GEPs) group of ADAMTSs. These enzymes break down chondroitin sulphate proteoglycans (CSPGs) which are key components of brain extracellular matrix (ECM).
openaire  

Serum versican and adamts-1 levels adolescent polycystic ovary syndrome (APCOS) [PDF]

open access: yesFertility and Sterility, 2015
ÖZLER, SİBEL   +5 more
openaire   +3 more sources

Investigation of ADAM17 and ADAMTS-1, -4 and -5 in liver carcinoma. [PDF]

open access: yes
Background: Proteolytic enzymes are important mediators of cellular proliferation, angiogenesis and remodelling of the extracellular matrix (ECM); all processes required for tumour growth and metastasis. However, the studies of proteolytic enzymes in hepatic tumours, both primary and metastatic, have largely been limited to specific matrix ...
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HEP3B hücrelerinde vegf sitokininin adamts-1 geni üzerine etkilerinin belirlenmesi

open access: yes, 2015
ADAMTS-1 (A disintegrin and metalloproteinase with thrombospondin motifs-1), Trombospondin tip I motifleri ile ADAM ailesi üyelerinden ayrılmakta ve günümüzde ADAMTS ailesinin ilk üyesi olarak tanımlanmaktadır. Yapılan çalışmalar ADAMTS-1'in VEGF'i (Vascular Endothelial Growth Factor) baskılayan bir protein olduğunu göstermektedir.
openaire   +3 more sources

Identification of substrate for ADAMTS-1 protease and roles of ADAMTS-1 in organogenesis

open access: yesIdentification of substrate for ADAMTS-1 protease and roles of ADAMTS-1 in organogenesis
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Role of ADAMTS-1 in Atherosclerosis [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2005
Objective— We investigated the potential role of ADAMTS-1 (a disintegrin and metalloprotease with thrombospondin motif type I) in atherogenesis. Methods and Results— ADAMTS-1 is expressed at the highest levels in the aorta when
Peter Brodin, Birgitta Rosengren
exaly   +3 more sources

Full-length ADAMTS-1 and the ADAMTS-1 fragments display pro- and antimetastatic activity, respectively [PDF]

open access: yesOncogene, 2005
The exact role of a disintegrin and metalloproteinase with thrombospondin motifs-1 (ADAMTS-1) and the underlying mechanism of its involvement in tumor metastasis have not been established. We have now demonstrated that overexpression of ADAMTS-1 promotes pulmonary metastasis of TA3 mammary carcinoma and Lewis lung carcinoma cells and that a proteinase ...
Yu Q
exaly   +3 more sources

Differential gene expression of ADAMTS-1, ADAMTS-9 and TIMP-3 in periodontitis

Biotechnic & Histochemistry, 2022
A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) are metalloproteinases that bind to components of the extracellular matrix (ECM) to regulate tissue remodeling and homeostasis. ADAMTS can be inhibited by tissue inhibitors of metalloproteinases (TIMPs). Expression of ADAMTS increases under inflammatory conditions.
M. Ayşe Tayman, İsmail Koyuncu
openaire   +3 more sources

Adamts 1, 4, 5, 8, and 9 in Early Pregnancies

Fetal and Pediatric Pathology, 2017
The aim of this study was to immunohistochemically investigate the presence and localization of ADAMTS 1, 4, 5, 8 and 9 in decidual and chorionic tissues in first trimester pregnancy losses.This study was conducted with early pregnancy failure decidual and chorionic tissue samples from 36 pregnant women in the first trimester of pregnancy (ongoing ...
Müberra, Namli Kalem   +3 more
openaire   +2 more sources

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