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The role of ADAMTS-1, -4 and -5 in multiple sclerosis. [PDF]
ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-1, -4 and -5 are secreted enzymes which are members of the glutamyl endopeptidases (GEPs) group of ADAMTSs. These enzymes break down chondroitin sulphate proteoglycans (CSPGs) which are key components of brain extracellular matrix (ECM).
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Serum versican and adamts-1 levels adolescent polycystic ovary syndrome (APCOS) [PDF]
ÖZLER, SİBEL +5 more
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Investigation of ADAM17 and ADAMTS-1, -4 and -5 in liver carcinoma. [PDF]
Background: Proteolytic enzymes are important mediators of cellular proliferation, angiogenesis and remodelling of the extracellular matrix (ECM); all processes required for tumour growth and metastasis. However, the studies of proteolytic enzymes in hepatic tumours, both primary and metastatic, have largely been limited to specific matrix ...
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HEP3B hücrelerinde vegf sitokininin adamts-1 geni üzerine etkilerinin belirlenmesi
ADAMTS-1 (A disintegrin and metalloproteinase with thrombospondin motifs-1), Trombospondin tip I motifleri ile ADAM ailesi üyelerinden ayrılmakta ve günümüzde ADAMTS ailesinin ilk üyesi olarak tanımlanmaktadır. Yapılan çalışmalar ADAMTS-1'in VEGF'i (Vascular Endothelial Growth Factor) baskılayan bir protein olduğunu göstermektedir.
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Identification of substrate for ADAMTS-1 protease and roles of ADAMTS-1 in organogenesis
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Research Progress of ADAMTS-1 in Obstetrics and Gynecology Diseases
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Role of ADAMTS-1 in Atherosclerosis [PDF]
Objective— We investigated the potential role of ADAMTS-1 (a disintegrin and metalloprotease with thrombospondin motif type I) in atherogenesis. Methods and Results— ADAMTS-1 is expressed at the highest levels in the aorta when
Peter Brodin, Birgitta Rosengren
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Full-length ADAMTS-1 and the ADAMTS-1 fragments display pro- and antimetastatic activity, respectively [PDF]
The exact role of a disintegrin and metalloproteinase with thrombospondin motifs-1 (ADAMTS-1) and the underlying mechanism of its involvement in tumor metastasis have not been established. We have now demonstrated that overexpression of ADAMTS-1 promotes pulmonary metastasis of TA3 mammary carcinoma and Lewis lung carcinoma cells and that a proteinase ...
Yu Q
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Differential gene expression of ADAMTS-1, ADAMTS-9 and TIMP-3 in periodontitis
Biotechnic & Histochemistry, 2022A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) are metalloproteinases that bind to components of the extracellular matrix (ECM) to regulate tissue remodeling and homeostasis. ADAMTS can be inhibited by tissue inhibitors of metalloproteinases (TIMPs). Expression of ADAMTS increases under inflammatory conditions.
M. Ayşe Tayman, İsmail Koyuncu
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Adamts 1, 4, 5, 8, and 9 in Early Pregnancies
Fetal and Pediatric Pathology, 2017The aim of this study was to immunohistochemically investigate the presence and localization of ADAMTS 1, 4, 5, 8 and 9 in decidual and chorionic tissues in first trimester pregnancy losses.This study was conducted with early pregnancy failure decidual and chorionic tissue samples from 36 pregnant women in the first trimester of pregnancy (ongoing ...
Müberra, Namli Kalem +3 more
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