Results 81 to 90 of about 380 (133)

Daratumumab for relapsed refractory immune thrombotic thrombocytopenic purpura: initial response and long-term follow-up

Research and Practice in Thrombosis and Haemostasis
Background: Management of patients with refractory or frequently relapsing (r/r) immune thrombotic thrombocytopenic purpura (iTTP) remains challenging, with no established consensus on optimal therapeutic strategies.
Roman Schimmer, Jana van den Berg, Marissa Schraner, Alice Trinchero, Andreas Holbro, Johanna A. Kremer Hovinga, Jan-Dirk Studt   +6 more
doaj   +1 more source

Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

International Journal of Molecular Medicine
Skeletal muscle satellite cells (MuSCs) play a central role in muscle regeneration; however, their capacity declines with age, contributing to sarcopenia. A disintegrin and metalloproteinase with thrombospondin motifs‑1 (ADAMTS‑1) regulates MuSC activation and differentiation. The present study aimed to investigate the potential of recombinant ADAMTS‑1
Kim, Jin-Hwa, Lee, Sang-Hyup, Kim, Sang-Yoon, Kim, Jeong-Won, Jeong, Ji-Soo, Chung, Eun-Hye, Lee, Su-Ha, Kim, Chang-Yeop, Choi, Bong-Keun, Ko, Je-Won, Kim, Tae-Won   +10 more
openaire   +2 more sources

Comparative assessment of changes ADAMTS-13/von Willebrand factor axis in singleton and bichorial biamniotic pregnancy

Акушерство, гинекология и репродукция
Aim: to compare changes in the ADAMTS-13 metalloproteinase/von Willebrand factor (vWF) axis in pregnant women with spontaneous or following in vitro fertilization (IVF) singleton and bichorial biamniotic pregnancies.Materials and Methods.
F. Е. Yagubova, V. O. Bitsadze, N. V. Samburova, J. Kh. Khizroeva, A. D. Makatsariya   +4 more
doaj   +1 more source

Investigation of ADAMTS-13 levels in patients with COVID-19 infection

Journal of Infection in Developing Countries
Introduction: Coronavirus disease 2019 (COVID-19) patients are predisposed to thrombotic events. COVID-19 coagulopathy can be associated with ADAMTS-13 (a disintegrin-like and metalloprotease with thrombospondin type I repeats 13) levels. ADAMTS-13, the
Hüseyin H Kutlu, Arzu Sahin, Soycan Mizrak, Abdurrahman Yilmaz, Songul Doganay, Serdar Gungor, Sema Yilmaz   +6 more
doaj   +1 more source

Gene expression and immunohistochemistry analysis of ADAMTS-1 and its substrates in odontogenic keratocyst

Diagnostic Pathology
Considering the significant participation of the microenvironment in the local aggressiveness of odontogenic keratocysts, this study aims to evaluate the expression of ADAMTS-1 and its substrates, versican, aggrecan and brevican in this locally invasive odontogenic cyst.Immunohistochemistry and polymerase chain reaction (PCR) were conducted on 30 cases
Osvaldo Rodrigues de Souza Neto, Antonia Taiane Lopes de Moraes, Hellen Thais Fuzii, Antonio Guilherme Maneschy Faria, Vanessa Morais Freitas, Maria Sueli da Silva Kataoka, Sérgio de Melo Alves, João de Jesus Viana Pinheiro   +7 more
openaire   +3 more sources

Severe ADAMTS-13 deficiency without hemolysis as a cause of cryptogenic stroke: A single center case series

Journal of Stroke and Cerebrovascular Diseases
Introduction: Cerebral Infarction due to Severe ADAMTS-13 Deficiency (CISAD) remains an underrecognized cause of cryptogenic stroke. Despite the absence of classic hematologic features, CISAD confers a risk of recurrent ischemic events if not promptly ...
Johanna Seiden, MD, MPH, Juan Felipe Daza-Ovalle, MD, Zhengrui Xiao, MD, Olga Rubalsky, MD, Irina Murakhovskaya, MD, Ellen Friedman, MD, Kathryn Kirchoff-Torres, MD, Daniel Labovitz, MD, MS, Charles Esenwa, MD, MS   +8 more
doaj   +1 more source

İnsan ADAMTS-1 geninin transkripsiyonel regülasyonu

, 2012
179
openaire   +3 more sources

Östrüs siklusu boyunca sıçan ovaryumunda ADAMTS-1 metalloproteinazının dağılımı

, 2023
A Disintegrin and Metalloproteinase with Thrombospondins Motifs 1 (ADAMTS-1), ovaryumdaki foliküler gelişim sırasında folikül bütünlüğünü ve işlevselliğini sürdürmek amacıyla yeniden şekillenmede rol oynayan bir metalloproteinazdır. Bu çalışmada, dişi sıçanların farklı östrüs siklusu evrelerindeki ovaryum dokularında ADAMTS-1 immünolokalizasyonu ...
Ak, Tuba Parlak, Bulmuş, Özgür, Yaman, Mine, Bayrakdar, Ali   +3 more
openaire   +2 more sources

Predictive value of ADAMTS-13 on concealed chronic renal failure in COPD patients

International Journal of COPD, 2017
Mian Zeng, Qingui Chen, Wenjie Liang, Wanmei He, Haichong Zheng, Chunrong Huang Department of Medical Intensive Care Unit, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China Background: Impaired renal function is often neglected ...
Zeng M, Chen QG, Liang WJ, He WM, Zheng HC, Huang CR   +5 more
doaj  

Adamts-1 Is Essential for the Development and Function of the Urogenital System1 [PDF]

Biology of Reproduction, 2004
L. Mittaz, D.L. Russell, T. Wilson, M. Brasted, J. Tkalcevic, L.A. Salamonsen, P.J. Hertzog, M.A. Pritchard   +7 more
openaire   +1 more source