Integrative genomic and functional characterization of ADAMTS3 reveals its inflammatory regulation via NF-κB and STAT3 pathways in osteosarcoma. [PDF]
J Cell Commun SignalAymaz EM +4 more
europepmc +1 more source
Mitochondrial dysfunction activates ADAMTS-5 expression via mt-dsRNA-PKR-Spi-1 axis in osteoarthritic chondrocytes. [PDF]
iScienceMu Y +8 more
europepmc +1 more source
ADAMTS-7 Increase Contributes to Worsened Neurological Outcome in Mice on High Fat Diet. [PDF]
CNS Neurosci TherXu Y, Li J, Zuo Z.
europepmc +1 more source
Computational Insights into Flavonoids for ADAMTS-5 Exosite Inhibition in Knee Osteoarthritis: Docking, MD Simulations, and Machine Learning-Guided Structure Prediction. [PDF]
MoleculesBhatia M, Duraisamy N, Cherkaoui M.
europepmc +1 more source
Depletion of aquaporin 1 decreased ADAMTS-4 expression in human chondrocytes
Depletion of aquaporin 1 decreased ADAMTS-4 expression in human chondrocytesInflammation serves an important role in the progression of osteoarthritis (OA), and IL-1β may act as a catabolic factor on cartilage, reducing the synthesis of primary cartilage components type II collagen and aggrecan. Aquaporin 1 (AQP1) is a 28-kDa water channel formed of six transmembrane domains on the cell membrane.
openaire +1 more source
Daratumumab in relapse-refractory immune-mediated thrombotic thrombocytopenic purpura: additional evidence for its efficacy. [PDF]
Res Pract Thromb HaemostCoppo P.
europepmc +1 more source
Discovery of Potent and Selective Inhibitors for ADAMTS-4 through DNA-Encoded Library Technology (ELT). [PDF]
ACS Med Chem Lett, 2015 Ding Y +13 more
europepmc +1 more source
Solving another piece of the thrombotic thrombocytopenic purpura puzzle? [PDF]
Res Pract Thromb HaemostEvangelidis P, Gavriilaki E.
europepmc +1 more source
<i>ADAMTS</i> and <i>ADAMTSL</i> mutations in connective tissue disorders. [PDF]
Physiology (Bethesda)Alcocer AD, Rush EH, Mead TJ.
europepmc +1 more source