Results 101 to 110 of about 11,934 (162)

ADAMTS-5 Decreases in Coronary Arteries and Plasma from Patients with Coronary Artery Disease. [PDF]

Dis Markers, 2019
Wang Z, Ye D, Ye J, Wang M, Liu J, Jiang H, Xu Y, Zhang J, Chen J, Wan J.   +9 more
europepmc   +1 more source

Association of ADAMTS-5 gene polymorphisms with the susceptibility to knee osteoarthritis in a Chinese Han population. [PDF]

J Orthop Surg Res
Gao S, Jia M, Wang J, Sun Q, Liu F, Yu L, Guo Y, Li N, Wei L.   +8 more
europepmc   +1 more source

Translational pharmacokinetic and pharmacodynamic modelling of the anti-ADAMTS-5 NANOBODY^® (M6495) using the neo-epitope ARGS as a biomarker. [PDF]

J Pharmacokinet Pharmacodyn
Pereira JNS, Ottevaere I, Serruys B, Guehring H, Ladel C, Lindemann S.   +5 more
europepmc   +1 more source

Erratum: Treatment of Dystrophic mdx Mice with an ADAMTS-5 Specific Monoclonal Antibody Increases the Ex Vivo Strength of Isolated Fast Twitch Hindlimb Muscles. Biomolecules 2020, 10, 416. [PDF]

Biomolecules, 2020
Addinsall AB, Forgan LG, McRae NL, Kelly RW, McDonald PL, McNeill B, McCulloch DR, Stupka N.   +7 more
europepmc   +1 more source

ADAMTS-9 in Mouse Cartilage Has Aggrecanase Activity That Is Distinct from ADAMTS-4 and ADAMTS-5. [PDF]

Int J Mol Sci, 2019
Rogerson FM, Last K, Golub SB, Gauci SJ, Stanton H, Bell KM, Fosang AJ.   +6 more
europepmc   +1 more source

Safety, Tolerability, and Pharmacodynamics of the ADAMTS-5 Nanobody M6495: Two Phase 1, Single-Center, Double-Blind, Randomized, Placebo-Controlled Studies in Healthy Subjects and Patients With Osteoarthritis. [PDF]

ACR Open Rheumatol
Bihlet AR, Balchen T, Goteti K, Sonne J, Ladel C, Karsdal MA, Ona V, Moreau F, Waterhouse R, Bay-Jensen AC, Guehring H.   +10 more
europepmc   +1 more source

Matrix-degrading protease ADAMTS-5 cleaves inter-α-inhibitor and releases active heavy chain 2 in synovial fluids from arthritic patients. [PDF]

J Biol Chem, 2019
Scavenius C, Poulsen EC, Thøgersen IB, Roebuck M, Frostick S, Bou-Gharios G, Yamamoto K, Deleuran B, Enghild JJ.   +8 more
europepmc   +1 more source

Effect of Mechanical Stress in Combination with Verapamil on Levels of Aggrecan and ADAMTS-5 mRNAs and Proteins in Human Osteoarthritic Chondrocyte/Agarose Constructs. [PDF]

Chin Med J (Engl), 2018
Luo D, Shen Y, Lyu JQ, Fan YQ, Huang DH, Lin WL, Shen HM, Xu HJ, Guan JL.   +8 more
europepmc   +1 more source

Screening for selective ADAMTS-5 substrates to monitor proteinase activity

, 2021
openaire   +2 more sources

ADAMTS-5 takes centre stage in new developments for aggrecanase inhibitors

Osteoarthritis and Cartilage, 2015
openaire   +3 more sources