P129 | Diagnostic pathway for thrombotic thrombocytopenic purpura: Case study
Italian Journal of MedicinePremises: TTP is characterized by MAHA with thrombocytopenia and organ ischemia. The diagnosis is confirmed by a severe deficiency in ADAMTS 13 activity, either congenital or immune-mediated.
doaj +1 more source
Erratum: Treatment of Dystrophic mdx Mice with an ADAMTS-5 Specific Monoclonal Antibody Increases the Ex Vivo Strength of Isolated Fast Twitch Hindlimb Muscles. Biomolecules 2020, 10, 416. [PDF]
Biomolecules, 2020 Addinsall AB +7 more
europepmc +1 more source
Translational pharmacokinetic and pharmacodynamic modelling of the anti-ADAMTS-5 NANOBODY® (M6495) using the neo-epitope ARGS as a biomarker. [PDF]
J Pharmacokinet PharmacodynPereira JNS +5 more
europepmc +1 more source
Effect of Mechanical Stress in Combination with Verapamil on Levels of Aggrecan and ADAMTS-5 mRNAs and Proteins in Human Osteoarthritic Chondrocyte/Agarose Constructs. [PDF]
Chin Med J (Engl), 2018 Luo D +8 more
europepmc +1 more source
A Disintegrin and Metalloproteinase with Thrombospondin Motifs-5 (ADAMTS-5) Forms Catalytically Active Oligomers. [PDF]
J Biol Chem, 2016 Kosasih HJ +10 more
europepmc +1 more source
Screening for selective ADAMTS-5 substrates to monitor proteinase activity
, 2021 openaire +2 more sources
ADAMTS-5 takes centre stage in new developments for aggrecanase inhibitors
Osteoarthritis and Cartilage, 2015 openaire +3 more sources
Integrative genomic and functional characterization of ADAMTS3 reveals its inflammatory regulation via NF-κB and STAT3 pathways in osteosarcoma. [PDF]
J Cell Commun SignalAymaz EM +4 more
europepmc +1 more source