Results 51 to 60 of about 12,658,346 (176)
Research and Practice in Thrombosis and Haemostasis, 2021 Recently, treatment of immune‐mediated thrombotic thrombocytopenic purpura (ITTP) has changed with the advent of caplacizumab in clinical practice.
Francesca Palandri +8 more
doaj +1 more source
Effect of Dexamethasone on Cartilage Degeneration in Rats with Collagen-induced Arthritis
Shiyan dongwu yu bijiao yixue, 2022 ObjectiveTo establish a rat model of collagen-induced arthritis (CIA), a rat model of rheumatoid arthritis, and to study the protective effect of dexamethasone (DEX) on cartilage in CIA rats.MethodsThirty Wistar rats were randomly divided into three ...
XU Bingxin +3 more
doaj +1 more source
Philogenetic Analysis of ADAMTS-4 and ADAMTS-5 Structures
Natural Systems and Resources, 2020 ADAMTS-4 and -5 are aggrecanases that are involved in the development of osteoarthrosis by breaking aggrecan at various binding sites, of which cleavage in the Glu373-Ala374 bond plays the most important role in pathogenesis. Therefore, studying them is an urgent task to this day. Now, the structural features of these enzymes have already been studied,
Anastasia Korchagina, Pavel Krylov
openaire +1 more source
Orthopaedic Journal of Sports Medicine, 2021 Objectives: Intra-articular hematoma are caused by articular injury such as ligament rupture or intra-articular fracture and following knee surgery. It has been reported that intra-articular hematoma leads to cartilage degeneration. Exposure of articular
Takuya Tajima MD, PhD +4 more
doaj +1 more source
Expression of ADAMTS-5 in deformed human temporomandibular joint discs.
Histology and histopathology, 2008 To study the expression of a disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) in tissue samples of deformed human temporomandibular joint (TMJ) discs and cells obtained from the discs.Eleven adult human TMJ discs (nine diseased discs and two normal discs) were used in this study.
Matsumoto, Takashi +4 more
openaire +3 more sources
European Journal of Obstetrics, Gynecology, and Reproductive BiologyPURPOSE Endometrial polyps (EPs) are common gynecological disorders for which no clear etiology has been found. ADAMTS have been associated with a variety of diseases.
Jiejie Nian +7 more
semanticscholar +1 more source
Advanced Science, EarlyView.Both SVF and CD31+ SVF improve spontaneous osteoarthritis, but CD31+ enrichment refines the therapeutic profile rather than broadly enhancing all effects. More distinct benefits are observed in extracellular matrix remodeling, osteochondral integrity, and subchondral/trabecular bone preservation, supporting CD31+‐enriched SVF as a biologically enhanced
Sijia Zhou +16 more
wiley +1 more source
Hematology, Transfusion and Cell Therapy, 2021 Introdução: A PTT, doença rara que atinge 3/milhão/ano em adultos, é considerada emergência médica com mortalidade de 95% se não tratada. Trata-se de microangiopatia trombótica, causada por deficiência da enzima ADAMTS 13 e caracterizada por oclusão ...
VHR Carvalho +8 more
doaj +1 more source
Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley +1 more source
Orthopaedic Surgery, 2021 Objective To explore the possible way of proline‐serine–threonine phosphatase‐interacting protein 2 (PSTPIP2) influencing diabetes mellitus‐osteoarthritis (DM‐OA) progression.
Ming Li +4 more
doaj +1 more source