Results 51 to 60 of about 15,848 (207)
Increased plasma von Willebrand factor antigen levels but normal von Willebrand factor cleaving protease (ADAMTS13) activity in preeclampsia. [PDF]
, 2009 The activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease is low in several conditions, including HELLP (haemolysis, elevated liver enzymes, and low platelet count) syndrome.
Hársfalvi, Jolán +9 more
core +1 more source
ADAMTS-13 gene expression in antiphospholipid syndrome
Turkish Journal of Hematology, 2011 OBJECTIVE: Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by recurrent thrombosis and fetal mortality. Thrombotic microangiopathy (TMA) is an important histological finding in catastrophic APS (CAPS) and in APS patients with ...
Veysel Sabri Hançer +2 more
doaj +3 more sources
ADAMTS-13 proteolyzed by thrombin has reduced affinity for von Willebrand factor (VWF)
, 2011 (A) 6 n ADAMTS-13, 60 n thrombin-cleaved ADAMTS-13 (ADAMTS-13/FIIa) or 60 n thrombin-cleaved ADAMTS-13/6 n ADAMTS-13 (10:1 mix) was incubated with 10 n purified plasma-derived VWF in the presence of 1.5 urea and 5 m BaCl.
C K N K CHION (48919) +4 more
core +1 more source
Gene Expression and Immunochemistry Analysis of ADAMTS-1 and Versican in Ameloblastoma
International Journal of Dentistry, 2022 Background. Ameloblastoma is a benign but locally invasive odontogenic epithelial tumor, associated with a high recurrence rate after treatment. The action of enzymes of the metalloproteinase family is important to the degraded extracellular matrix ...
Osvaldo Rodrigues de Souza Neto +4 more
doaj +1 more source
Biomolecules, 2020 Aberrant extracellular matrix synthesis and remodeling contributes to muscle degeneration and weakness in Duchenne muscular dystrophy (DMD). ADAMTS-5, a secreted metalloproteinase with catalytic activity against versican, is implicated in myogenesis and ...
Alex B. Addinsall +7 more
doaj +1 more source
The effect of protease inhibitors on the induction of osteoarthritis-related biomarkers in bovine full-depth cartilage explants. [PDF]
PLoS ONE, 2015 The specific degradation of type II collagen and aggrecan by matrix metalloproteinase (MMP)-9, -13 and ADAMTS-4 and -5 (aggrecanase-1 and -2) in the cartilage matrix is a critical step in pathology of osteoarthritis (OA).
Yi He +7 more
doaj +1 more source
Arthritis Care &Research, Accepted Article.Objective For cartilage morphology to serve as a scalable endpoint in clinical trials, analyses should be performed automatically without human interaction. To clinically validate artificial intelligence (AI)‐based analysis, we studied cartilage loss from MRI prior to knee replacement.
Felix Eckstein +3 more
wiley +1 more source
MAB 1810 (Millipore) also recognizes ADAMTS-1 in nuclei.
, 2016 (A) Immunofluorescence was performed in MCF-10A cells with another commercially available antibody against ADAMTS-1, and the same labeling pattern is observed.
Ruy G. Jaeger (618268) +4 more
core +1 more source
Saudi Journal of Kidney Diseases and Transplantation, 2018 Severe deficiency of ADAMTS-13 leads to thrombotic thrombocytopenic purpura. Few studies have reported reduced activity of ADAMTS-13 in patients with atypical and typical hemolytic uremic syndrome (HUS).
Naglaa A Khalifa +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande +9 more
wiley +1 more source