Results 81 to 90 of about 12,128 (176)

The roles of ADAMTS in angiogenesis and cancer

Tumor Biology, 2015
Angiogenesis is an indispensable mechanism involved in both physiological processes and various pathological conditions, such as inflammation, aberrant wound healing, tumor progression, and metastasis. Among many angiogenic stimulators and inhibitors, vascular endothelial growth factor (VEGF) is regarded as one of the most important members of the ...
Yi, Sun, Jintuan, Huang, Zuli, Yang
openaire   +2 more sources

RELATIONSHIP OF ADAMTS WITH BIOCHEMICAL PARAMETERS IN METABOLIC SYNDROME

Sabiad
Objective: The aim of our study was to investigate the potential of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) proteins, which are thought to change in levels as a result of the deterioration of the extracellular matrix in ...
Semiramis Doğan Zeybek, Adnan Adil Hişmioğulları   +1 more
doaj   +1 more source

The role of ADAMTS‐13 and von Willebrand factor in cancer patients: Results from the Vienna Cancer and Thrombosis Study

Research and Practice in Thrombosis and Haemostasis, 2019
Essentials Cancer is associated with increased risk of developing venous thrombosis. Cancer patients were studied for ADAMTS‐13 and VWF levels and occurrence of venous thrombosis.
Hanna L. Obermeier, Julia Riedl, Cihan Ay, Silvia Koder, Peter Quehenberger, Rupert Bartsch, Alexandra Kaider, Christoph C. Zielinski, Ingrid Pabinger   +8 more
doaj   +1 more source

Mechanistic insight into multiple antibody binding to ADAMTS13 in immune thrombotic thrombocytopenic purpura

Research and Practice in Thrombosis and Haemostasis
Background: Antibody-mediated inhibition of von Willebrand factor (VWF) cleavage by ADAMTS-13 results in immune thrombotic thrombocytopenic purpura (iTTP).
Konstantine Halkidis, Chan Meng, Vikram G. Pillai, Madison Shay, Szumam Liu, X. Long Zheng   +5 more
doaj   +1 more source

Comparative assessment of changes ADAMTS-13/von Willebrand factor axis in singleton and bichorial biamniotic pregnancy

Акушерство, гинекология и репродукция
Aim: to compare changes in the ADAMTS-13 metalloproteinase/von Willebrand factor (vWF) axis in pregnant women with spontaneous or following in vitro fertilization (IVF) singleton and bichorial biamniotic pregnancies.Materials and Methods.
F. Е. Yagubova, V. O. Bitsadze, N. V. Samburova, J. Kh. Khizroeva, A. D. Makatsariya   +4 more
doaj   +1 more source

Inhibition of MMPs and ADAM/ADAMTS

Biochemical Pharmacology, 2019
Matrix metalloproteinases (MMPs), A Disintegrin and Metalloproteinase (ADAM) and A Disintegrin and Metalloproteinase with Thrombospondin Motif (ADAMTS) are zinc-dependent endopeptidases that play a critical role in the destruction of extracellular matrix proteins and, the shedding of membrane-bound receptor molecules in various forms of arthritis and ...
openaire   +3 more sources

Association Between Plasma ADAMTS-7 Levels and Diastolic Dysfunction in Patients with Type 2 Diabetes Mellitus

Medicina
A disintegrin and metalloproteinase with thrombospondin motifs-7 (ADAMTS-7) belongs to the family of metalloproteinases that contributes to tissue homeostasis during morphogenesis and reproduction. These metalloproteinases regulate various cell functions
Asimina Ganotopoulou, Emmanouil Korakas, Loukia Pliouta, Aikaterini Kountouri, Sotirios Pililis, Stamatios Lampsas, Ignatios Ikonomidis, Loukianos S. Rallidis, Athanasia Papazafiropoulou, Andreas Melidonis, Vaia Lambadiari   +10 more
doaj   +1 more source

The Relationship Between ADAMTS‐4 and ADAMTS‐5 Enzyme Levels in Patients With Degenerative Disc Disease: A Prospective Biochemical Study

JOR Spine
Study Design Prospective biochemical study of comparison of A Disintegrin and Metalloproteinase with Thrombospondin motifs‐4 (ADAMTS‐4) and A Disintegrin and Metalloproteinase with Thrombospondin motifs 5 (ADAMTS5) levels in preoperative and ...
Cansu Tuncer, Emin Mehmet Eminoğlu, Ömer Emre Yağlı, Gülçin Baş, Ahmet Sancar Topal, Ece Onur, Habib Özdemir, Şemsi Güliz Yılmaz, Gülgün Yılmaz Ovalı, Cüneyt Temiz   +9 more
doaj   +1 more source

A comparative study of anti–ADAMTS-13 antibody dynamics in immune-mediated thrombotic thrombocytopenic purpura

Research and Practice in Thrombosis and Haemostasis
Background: Thrombotic thrombocytopenic purpura, particularly its immune-mediated variant (iTTP), necessitates accurate diagnostic approaches for effective management.
Maria Rita Cozzi, Fabio Del Ben, Chiara Corso, Agostino Steffan   +3 more
doaj   +1 more source

ADAMTS-1 Expression in Cumulus Cells: A Biomarker for Oocyte Maturity

پزشکی بالینی ابن سینا, 2018
Background and Objective: Cumulus cells regulate oocyte maturation through bilateral communication during follicular growth. Expression of disintegrin-like and metalloproteinase with thrombospondin type I motifs-1 (ADAMTS-1) is essential for structural ...
Sepide Gohari Taban, Iraj Amiri, Massoud Saidijam, Sara Soleimani Asl, Mahnaz Yavangi, Elham Khanlarzadeh, Tayebe Artimani   +6 more
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