Results 81 to 90 of about 14,009 (226)

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai, Hirohiko Aikawa, Yoshiaki Morita, Keiko Ohta‐Ogo, Teruo Noguchi   +4 more
wiley   +1 more source

Integrative genomic and functional characterization of ADAMTS3 reveals its inflammatory regulation via NF‐κB and STAT3 pathways in osteosarcoma

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Abstract Osteosarcoma (OS) is an aggressive bone malignancy characterized by genomic instability and extensive extracellular matrix (ECM) remodeling. Members of the ADAMTS family are matrix‐associated proteases implicated in tumorigenesis; however, their roles in OS remain poorly defined. This study provides a comprehensive genomic, transcriptomic, and
Ehed Muhammed Aymaz, Meltem Alper, Feyza Nur Sav, Tuğşen Aydemir, Feray Köçkar   +4 more
wiley   +1 more source

Arsenicosis, possibly from contaminated groundwater, associated with noncirrhotic intrahepatic portal hypertension. [PDF]

, 2016
BACKGROUND AND AIMS: Idiopathic noncirrhotic intrahepatic portal hypertension (NCIPH), a chronic microangiopathy of the liver caused by arsenicosis from use of contaminated groundwater, was reported from Asia.
Amirtharaj, GJ, Balasubramanian, KA, Christudoss, P, Eapen, CE, Elias, E, Fleming, JJ, George, R, Goel, A, Keshava, SN, Mackie, I, Ramachandran, A, Ramakrishna, B   +11 more
core   +1 more source

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, Volume 48, Issue 3, Page 521-530, June 2026.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source

Concentration and Subclass Distribution of Anti-ADAMTS13 IgG Autoantibodies in Different Stages of Acquired Idiopathic Thrombotic Thrombocytopenic Purpura

Frontiers in Immunology, 2018
BackgroundThe acquired form of idiopathic thrombotic thrombocytopenic purpura (TTP) is an autoimmune disease, in which the underlying deficiency of the ADAMTS13 protease is caused by autoantibodies, predominantly of the IgG isotype.
György Sinkovits, Ágnes Szilágyi, Péter Farkas, Dóra Inotai, Anikó Szilvási, Attila Tordai, Katalin Rázsó, Marienn Réti, Zoltán Prohászka   +8 more
doaj   +1 more source

Thrombotic microangiopathy and associated renal disorders [PDF]

, 2012
Thrombotic microangiopathy (TMA) is a pathological process involving thrombocytopenia, microangiopathic haemolytic anaemia and microvascular occlusion.
Barbour, T, Cohney, S, Hughes, P, Johnson, S   +3 more
core   +1 more source

Probable Catastrophic Antiphospholipid Syndrome Overlapping Hematological Abnormalities: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A young South Asian woman presented four weeks post‐miscarriage with fever, jaundice, edema, headache, neurological deficits, anemia, thrombocytopenia, proteinuria, hematuria, splenic infarct, and cerebral venous sinus thrombosis. Positive beta‐2 glycoprotein IgG and lupus anticoagulant supported probable CAPS.
Faseeh Ullah, Maryam Tariq, Marwa Farzand, Irha Riaz, Rizwan Rasol Khan, Kritick Bhandari   +5 more
wiley   +1 more source

Personalized Management of Cytopenias in Chronic Liver Disease: From Pathophysiology to Treatment Strategies

JGH Open, Volume 10, Issue 5, May 2026.
ABSTRACT Thrombocytopenia and leukopenia are among the most common hematological abnormalities in patients with chronic liver disease (CLD), particularly among those with cirrhosis. Thrombocytopenia and leukopenia are associated with increased risks of bleeding, infection, treatment delay, and poor clinical outcomes.
Xiaoxiao Wang, Shuyan Fu, Xiaohong Zhu, Yanping Zhao   +3 more
wiley   +1 more source

Determination of ADAMTS13 and Its Clinical Significance for ADAMTS13 Supplementation Therapy to Improve the Survival of Patients with Decompensated Liver Cirrhosis

International Journal of Hepatology, 2011
The liver plays a central role in hemostasis by synthesizing clotting factors, coagulation inhibitors, and fibrinolytic proteins. Liver cirrhosis (LC), therefore, impacts on both primary and secondary hemostatic mechanisms.
Masahito Uemura, Yoshihiro Fujimura, Saiho Ko, Masanori Matsumoto, Yoshiyuki Nakajima, Hiroshi Fukui   +5 more
doaj   +1 more source

ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice

TH Open, 2017
Background Inflammatory bowel disease (IBD) affects 1.6 million people in the United States. IBD is associated with an increased risk of thrombosis, which rises with disease activity.
Naamah L. Zitomersky, Melanie Demers, Kimberly Martinod, Maureen Gallant, Stephen M. Cifuni, Amlan Biswas, Scott Snapper, Denisa D. Wagner   +7 more
doaj   +1 more source