Results 91 to 100 of about 8,735 (203)
MedComm, Volume 6, Issue 12, December 2025.The present study firstly revealed that the predictive value of Lp(a) for worse outcomes in chronic coronary syndrome patients with A or B blood group was stronger than that in the O group, suggesting that ABO blood group measurement may be clinically helpful for decision‐making in Lp(a) intervention. ABSTRACT This study aimed to investigate the effect
Hui‐Hui Liu +14 more
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Scientific ReportsMesenchymal stem cells (MSCs) are known to facilitate angiogenesis and promote neo-vascularization via secretion of trophic factors. Here, we explored the molecular mechanism adopted by ADAMTS13 in modulating the expression of some key angiogenic markers
Srishti Dutta Gupta, Malancha Ta
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Cuproptosis‐Related Ferroptosis Gene Signature: A Prognostic Tool for Colon Cancer Patients
Cancer Reports, Volume 8, Issue 11, November 2025.ABSTRACT Background Ferroptosis and cuprotosis, two distinct mechanisms of programmed cell death, play key roles in colon cancer development. This study aimed to construct a prognostic model for predicting colon adenocarcinoma (COAD) prognosis based on the differential expression of cuproptosis‐related ferroptosis genes (CFRGs).
Yanlin Tan +7 more
wiley +1 more source
Scientific ReportsImmune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare and life-threatening blood disorder characterized by the formation of blood clots in small blood vessels. It is caused by antibodies targeting the A disintegrin and metalloprotease with
Heechun Kwak +13 more
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Nonsense-mediated mRNA decay in the ADAMTS13 gene caused by a 29-nucleotide deletion
Haematologica, 2008 Background In mammalian cells a regulatory mechanism, known as nonsense-mediated mRNA decay, degrades mRNA harboring premature termination codons. This mechanism is intron-dependent and functions as a quality control mechanism to eliminate abnormal ...
Isabella Garagiola +5 more
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Thrombotic Thrombocytopenic Purpura Revisited: Upshaw Schulman Syndrome in a 20-Year-Old Male [PDF]
, 2012 Case Report A 20-year-old male with no significant past medical history presented to an outside hospital with a two-week history of progressive fatigue, malaise and decreased appetite. Prior to these events, he had been in his usual state of health with
Peiris, MD, Niluk, Wang, MD, Judy
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MedwaveIntroduction Since the first description of Thrombotic Thrombocytopenic Purpura, caused by a severe deficiency of ADAMTS13, plasma exchange and immunosuppression have become standard treatments, allowing to decrease its high mortality rate.
Daniel Cathalifaud +6 more
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ABO Blood Groups and Cardiovascular Diseases [PDF]
, 2012 ABO blood groups have been associated with various disease phenotypes, particularly cardiovascular diseases. Cardiovascular diseases are the most common causes of death in developed countries and their prevalence rate is rapidly growing in developing ...
Ciarán J. Mooney +2 more
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The FASEB Journal, Volume 39, Issue 20, 31 October 2025.This graphical abstract presents the study of Resveratrol as a potential adjuvant therapy for Pleural Mesothelioma (PM), focusing on the epithelioid and biphasic histotypes using IST‐MES 2 and MSTO‐211H cell lines. Following 24 h of cell seeding, the cells were treated with Resveratrol, and various analyses were conducted to assess its effects.
Maria Rosa Iaquinta +9 more
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Current Issues in Molecular BiologyGenetic and epigenetic alterations of various biomolecules at the molecular level can contribute to the pathogenesis of hepatocellular carcinoma (HCC) and negative impact prognosis.
Durmuş Ayan +5 more
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