Results 91 to 100 of about 8,766 (203)
Scientific ReportsImmune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare and life-threatening blood disorder characterized by the formation of blood clots in small blood vessels. It is caused by antibodies targeting the A disintegrin and metalloprotease with
Heechun Kwak +13 more
doaj +1 more source
Atypical hemolytic uremic syndrome : update on the complement system and what is new [PDF]
, 2010 Atypical hemolytic uremic syndrome (aHUS) is a rare disease of microangiopathic hemolytic anemia, thrombocytopenia, and predominant renal impairment. It is characterized by the absence of Shiga toxin-producing bacteria as a triggering factor.
Dickenmann, Michael +2 more
core +1 more source
Case Reports in Hematology, Volume 2026, Issue 1, 2026.Aggressive natural killer cell leukemia (ANKL) is a rare, fulminant hematologic malignancy characterized by neoplastic proliferation of mature NK cells. It is frequently associated with Epstein–Barr virus (EBV) infection, although EBV‐negative cases have also been reported.
Jennifer Priessnitz +6 more
wiley +1 more source
The diagnosis and management of the haematologic manifestations of lupus [PDF]
, 2016 Haematological manifestations in systemic lupus erythematosus (SLE) are frequently observed. They are diverse and range from mild to severe.
Castro, SG +2 more
core +1 more source
Gemcitabine‐Induced Thrombotic Microangiopathy in Patient With Homozygous Deletion in CFHR1‐CFHR3
Case Reports in Oncological Medicine, Volume 2026, Issue 1, 2026.We present here the case of a 66‐year‐old female with a history of pancreatic adenocarcinoma who was on a chemotherapeutic regimen of nanoparticle albumin‐bound paclitaxel (nab‐paclitaxel) and gemcitabine after demonstrating local progression of her disease on the regimen of 5‐fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX).
Natasha Dziarnowski +4 more
wiley +1 more source
Current Issues in Molecular BiologyGenetic and epigenetic alterations of various biomolecules at the molecular level can contribute to the pathogenesis of hepatocellular carcinoma (HCC) and negative impact prognosis.
Durmuş Ayan +5 more
doaj +1 more source
Nonsense-mediated mRNA decay in the ADAMTS13 gene caused by a 29-nucleotide deletion
Haematologica, 2008 Background In mammalian cells a regulatory mechanism, known as nonsense-mediated mRNA decay, degrades mRNA harboring premature termination codons. This mechanism is intron-dependent and functions as a quality control mechanism to eliminate abnormal ...
Isabella Garagiola +5 more
doaj +1 more source
Internal tension in a collapsed polymer under shear flow and the connection to enzymatic cleavage of von Willebrand factor [PDF]
, 2016 By means of Brownian hydrodynamics simulations we show that the tension distribution along the contour of a single collapsed polymer in shear flow is inhomogeneous and above a threshold shear rate exhibits a double-peak structure when hydrodynamic ...
Lippok, Svenja +3 more
core +2 more sources
Atypical Thrombotic Presentation of Behçet′s Disease
Case Reports in Vascular Medicine, Volume 2026, Issue 1, 2026.As Behçet′s disease (BD) is a multisystem disorder that affects blood vessels, it predisposes patients to an increased risk of thrombosis. The vessels most commonly involved are those of the lower extremities, although the dural venous system may also be affected.
Hakeem Asad +3 more
wiley +1 more source
ADAMTS9, a member of the ADAMTS family, in Xenopus development [PDF]
, 2018 Extracellular matrix (ECM) remodeling by metalloproteinases is crucial during development. The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin type I motifs) enzymes are secreted, multi-domain matrix-associated zinc metalloendopeptidases ...
Boerboom +37 more
core +1 more source