Results 111 to 120 of about 3,354,179 (197)
Moschcowitz Disease in pediatric. [PDF]
Batna Journal of Medical SciencesHemichorea Moskowitz disease is a rare hematological disorder known to be an autoimmune disease in most patients. Most cases of thrombotic thrombopenic purpura (TTP) are caused by problems with an enzyme or protein in the blood called ADAMTS13.
Samira AGGOUNE, Mohamed Faouzi SEDDIKI
doaj +1 more source
ADAMTS13 mutations and polymorphisms in congenital thrombotic thrombocytopenic purpura
, 2010 Congenital thrombotic thrombocytopenic purpura (TTP) (also known as Upshaw-Schulman syndrome, USS) is a rare, life-threatening disease characterized by thrombocytopenia and microangiopathic hemolytic anemia, associated with the deficiency of the von ...
R. Palla +4 more
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Humoral immune response to ADAMTS13 in acquired thrombotic thrombocytopenic purpura
, 2011 The apparently spontaneous development of autoantibodies to ADAMTS13 in previously healthy individuals is a major cause of thrombotic thrombocytopenic purpura (TTP). Epitope mapping studies have shown that in most patients antibodies directed towards the
Hovinga, J A Kremer +9 more
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Novel ADAMTS13 mutations in an obstetric patient with upshaw-schulman syndrome [PDF]
, 2013 Upshaw-Schulman syndrome (USS) is a rarely reported congenital form of thrombotic thrombocytopenic purpura (TTP) that results from mutations in the ADAMTS13 gene.
Johanna A. Kremer Hovinga +7 more
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MedwaveIntroduction Since the first description of Thrombotic Thrombocytopenic Purpura, caused by a severe deficiency of ADAMTS13, plasma exchange and immunosuppression have become standard treatments, allowing to decrease its high mortality rate.
Daniel Cathalifaud +6 more
doaj +1 more source
Protein-RNA interactions: a structural analysis [PDF]
, 2001 A detailed computational analysis of 32 protein-RNA complexes is presented. A number of physical and chemical properties of the intermolecular interfaces are calculated and compared with those observed in protein-double-stranded DNA and protein-single ...
Daley, DT +9 more
core
ADAMTS13 activities and VWF levels in murine plasma.
, 2019 (A) ADAMTS13 activities in plasma from 2-, 6-, and 12-month-old WT, Adamts13−/−, APPPS1, and APPPS1–Adamts13−/− mice (n = 6). (B) VWF levels in plasma from 2-, 6-, and 12-month-old WT, Adamts13−/−, APPPS1, and APPPS1–Adamts13−/− mice (n = 6).
Ranran Wang (476935) +20 more
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ADAMTS13 missense variants associated with defective activity and secretion of ADAMTS13 in a patient with non-cirrhotic portal hypertension [PDF]
, 2017 BACKGROUND: Non-cirrhotic intrahepatic portal hypertension (NCIPH) is characterized by thrombotic microangiopathy of the portal venous system, low ADAMTS13 (a disintegrin-like and metalloproteinase with thrombospondin type 1 motifs-13), and high vWF (von
Venkatraman, A +11 more
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Vascular Specialist InternationalPurpose: This study aimed to investigate the relationship between the two biomarkers, von Willebrand factor (VWF) and ADAMTS13, and major adverse limb events (MALE) in patients with peripheral artery disease (PAD). Materials and Methods : After obtaining
Noa Agid +5 more
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Thrombotic Thrombocytopenic Purpura in Oman: Disease Burden and Outcomes
Oman Medical JournalObjectives: Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening autoimmune disorder; limited information about this disease is available from the Middle East.
Samata Al Dowaiki +4 more
doaj +1 more source