Results 111 to 120 of about 8,376 (205)

Marked elevation in plasma osteoprotegerin constitutes an early and consistent feature of cerebral malaria [PDF]

, 2016
Adherence of infected erythrocytes to vascular endothelium causes acute endothelial cell (EC) activation during Plasmodium falciparum infection.
Brophy, Teresa M, Chion, Alain, Craig, Alister G, Gegenbauer, Kristina, Moxon, Chris, O'Donnell, James S, O'Regan, Niamh, O'Sullivan, Jamie M, Preston, Roger JS, Smith, Owen P   +9 more
core   +1 more source

Can Plasma ADAMTS13 Differentiate Patients With Pulmonary Arterial Hypertension From Other Forms of Pulmonary Hypertension and Dyspnea Control PatientsTake-Home Points

CHEST Pulmonary
Background: Multimarker panels of blood-borne biomarkers could aid in shortening the diagnostic delay of pulmonary arterial hypertension (PAH). Research Question: Can any of the 61 proteins included in the study, related to pathways known to be involved ...
Kriss Kania, MD, Abdulla Ahmed, MD, Salaheldin Ahmed, MD, Adam Engel Sällberg, MD, Karin Tran-Lundmark, MD, PhD, Jørn Carlsen, MD, PhD, Göran Rådegran, MD, DMSc, MSc Eng Phys   +6 more
doaj   +1 more source

The functions of the A1A2A3 domains in von Willebrand factor include multimerin 1 binding. [PDF]

, 2016
Multimerin 1 (MMRN1) is a massive, homopolymeric protein that is stored in platelets and endothelial cells for activation-induced release. In vitro, MMRN1 binds to the outer surfaces of activated platelets and endothelial cells, the extracellular matrix (
Bihan, Dominique, de Groot, Philip G, Farndale, Richard W, Hayward, Catherine PM, Parker, D'Andra N, Sadler, J Evan, Sebastian, Silvie, Tasneem, Subia   +7 more
core   +3 more sources

The clinical implications of thrombocytopenia in adults with severe falciparum malaria: a retrospective analysis [PDF]

, 2015
BackgroundThrombocytopenia is a common finding in adults with severe falciparum malaria, but its clinical and prognostic utility is incompletely defined.MethodsClinical and laboratory data from 647 adults with severe falciparum malaria were analysed ...
Charunwatthana, Prakaykaew, Day, Nicholas P. J., Dondorp, Arjen M., Faiz, M. Abul, Hanson, Josh, Hasan, Mahatab Uddin, Hien, Tran Tinh, Kingston, Hugh W. F., Maude, Richard J., Mishra, Saroj K., Mohanty, Sanjib, Phu, Nguyen Hoan, Plewes, Katherine, Prapansilp, Panote, Price, Ric N., White, Nicholas J.   +15 more
core   +2 more sources

Role of Extracellular Hemoglobin in Thrombosis and Vascular Occlusion in Patients with Sickle Cell Anemia

Anemia, 2011
Sickle cell anemia (SCA) is a common hemolytic disorder caused by a gene mutation in the β-globin subunit of hemoglobin (Hb) and affects millions of people.
Zhou Zhou, Molly Behymer, Prasenjit Guchhait   +2 more
doaj   +1 more source

Regulation of ADAMTS13 by proteolitic enzymes

, 2007
Imperial Users ...
Lam, Jonathan Kai Yan, Lam, Jonathan Kai Yan   +1 more
core  

Vitamin B12 Deficiency with Pseudothrombotic Microangiopathy and Thrombotic Thrombocytopenic Purpura: Similarities and Differences [PDF]

, 2020
Buess, Charles, Germann, Alexander, Maloney, Eamon, Mohammed, Alaeldin   +3 more
core   +2 more sources

PROTEOLYTIC PROCESSING OF VON WILLEBRAND FACTOR BY ADAMTS13 AND LEUKOCYTE PROTEASES-rev1-MJHID-2013

Mediterranean Journal of Hematology and Infectious Diseases, 2014
ADAMTS13 is a 190 kDa zinc protease encoded by a gene located on chromosome 9q34.   This protease specifically hydrolyzes von Willebrand factor (VWF) multimers, thus causing VWF size reduction.
Raimondo De Cristofaro
doaj  

An Unusual Case of Rapidly Progressive Hyperbilirubinemia

Case Reports in Pediatrics, 2013
We present an unusual case of hyperbilirubinemia with rapid early progression leading to bilirubin encephalopathy in a term neonate. Despite early recognition and intervention, the total serum bilirubin reached a maximum level of 39 mg/dL at 32 hours of ...
Kimberly M. Thornton, Michael F. Nyp, Lejla Music Aplenc, Gary L. Jones, Shannon L. Carpenter, Erin M. Guest, Steven M. Shapiro, Winston M. Manimtim   +7 more
doaj   +1 more source

Clinical Dilemma in the Treatment of a Patient with Microangiopathic Haemolytic Anaemia, Thrombocytopaenia and Severe Hypertension [PDF]

, 2010
While haemolytic uraemic syndrome in children is predominantly associated with Shiga toxin -producing Escherichia coli (typically 0157:H7), some cases occur without associated diarrhoea, or as the manifestation of an underlying disorder other than ...
Castro, I, Gomes, D, Viegas, V
core