Small antimicrobial resistance proteins (SARPs): Small proteins conferring antimicrobial resistance [PDF]
arXiv, 2023 Small open reading frames are understudied as they have been historically excluded from genome annotations. However, evidence for the functional significance of small proteins in various cellular processes accumulates. Proteins with less than 70 residues can also confer resistance to antimicrobial compounds, including intracellularly-acting protein ...
arxiv
Plasma resistant atypical hemolytic uremic syndrome associated with a CFH mutation treated with eculizumab: a case report [PDF]
, 2015 INTRODUCTION: Thrombotic microangiopathies are a group of diseases presenting as microangiopathic hemolytic anemia, thrombocytopenia and end-organ dysfunction.
Abdulkadir Unsal +11 more
core +1 more source
Definitions, 2020 The ADAMTS13 enzyme processes a large protein called von Willebrand factor, which also plays a role in clot formation. The unprocessed form of von Willebrand factor interacts easily with cell fragments called platelets, which circulate in the bloodstream
semanticscholar +1 more source
Complex changes in von Willebrand factor-associated parameters are acquired during uncomplicated pregnancy. [PDF]
PLoS ONE, 2014 BACKGROUND:The coagulation protein von Willebrand Factor (VWF) is known to be elevated in pregnancy. However, the timing and nature of changes in VWF and associated parameters throughout pregnancy are not well understood.
Danielle N Drury-Stewart +7 more
doaj +1 more source
Protein Inference and Protein Quantification: Two Sides of the Same Coin [PDF]
arXiv, 2012 Motivation: In mass spectrometry-based shotgun proteomics, protein quantification and protein identification are two major computational problems. To quantify the protein abundance, a list of proteins must be firstly inferred from the sample. Then the relative or absolute protein abundance is estimated with quantification methods, such as spectral ...
arxiv
ADAMTS13 gene deletion enhances plasma high-mobility group box1 elevation and neuroinflammation in brain ischemia-reperfusion injury [PDF]
, 2018 Highly adhesive glycoprotein von Willebrand factor (VWF) multimer induces platelet aggregation and leukocyte tethering or extravasation on the injured vascular wall, contributing to microvascular plugging and inflammation in brain ischemia-reperfusion. A
Akitake, Yoshiharu +16 more
core
Síndrome Hemolítico Urémico Atípico en Cuidados Intensivos: Caso Clínico de un Adulto [PDF]
, 2016 info:eu-repo/semantics ...
Agudo, I +5 more
core +1 more source
The ADAMTS13–VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension
European Respiratory Journal, 2019 Chronic thromboembolic pulmonary hypertension (CTEPH) is an important consequence of pulmonary embolism that is associated with abnormalities in haemostasis.
M. Newnham +31 more
semanticscholar +1 more source
Clinical Case Reports, Volume 13, Issue 3, March 2025.ABSTRACT Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy (TMA) that is considered life‐threatening and caused by dysregulation of the complement system. Here, we report a previously healthy 8‐year‐old boy who presented with features of aHUS 1 week after viral symptoms during the COVID‐19 pandemic.
Parsa Lorestani +2 more
wiley +1 more source
Is the intrinsic disorder of proteins the cause of the scale-free architecture of protein-protein interaction networks? [PDF]
arXiv, 2006 In protein-protein interaction networks certain topological properties appear to be recurrent: networks maps are considered scale-free. It is possible that this topology is reflected in the protein structure. In this paper we investigate the role of protein disorder in the network topology.
arxiv