Results 111 to 120 of about 8,766 (203)

Thrombocytopeniak. [PDF]

, 2014
Thrombocytopenia means low platelet count. This is the most frequent cause of bleeding abnormalities. Petechias, purpuras, mucosal bleeding are typical clinical findings.
Domján, Gyula, Gadó, Klára
core   +1 more source

Thrombotic Thrombocytopenic Purpura in Oman: Disease Burden and Outcomes

Oman Medical Journal
Objectives: Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening autoimmune disorder; limited information about this disease is available from the Middle East.
Samata Al Dowaiki, Khalid Al Hashmi, Sulayma Al-Lamki, Muhana Al Muselhi, Murtadha Al-Khabori   +4 more
doaj   +1 more source

Thrombotic thrombocytopenic purpura: Description and analysis of 23 cases treated in Chile between 2017 and 2022

Medwave
Introduction Since the first description of Thrombotic Thrombocytopenic Purpura, caused by a severe deficiency of ADAMTS13, plasma exchange and immunosuppression have become standard treatments, allowing to decrease its high mortality rate.
Daniel Cathalifaud, Jean-Paul Manríquez, Benjamín Rodríguez, Gonzalo Eymin, Benjamín Sanfuentes, Joel Castellano, Andrés Valenzuela   +6 more
doaj   +1 more source

Regulation of ADAMTS13 by proteolitic enzymes

, 2007
Imperial Users ...
Lam, Jonathan Kai Yan, Lam, Jonathan Kai Yan   +1 more
core  

Can Plasma ADAMTS13 Differentiate Patients With Pulmonary Arterial Hypertension From Other Forms of Pulmonary Hypertension and Dyspnea Control PatientsTake-Home Points

CHEST Pulmonary
Background: Multimarker panels of blood-borne biomarkers could aid in shortening the diagnostic delay of pulmonary arterial hypertension (PAH). Research Question: Can any of the 61 proteins included in the study, related to pathways known to be involved ...
Kriss Kania, MD, Abdulla Ahmed, MD, Salaheldin Ahmed, MD, Adam Engel Sällberg, MD, Karin Tran-Lundmark, MD, PhD, Jørn Carlsen, MD, PhD, Göran Rådegran, MD, DMSc, MSc Eng Phys   +6 more
doaj   +1 more source

The role of complement in Streptococcus pneumoniae-associated haemolytic uraemic syndrome [PDF]

, 2013
Background. Atypical forms of haemolytic uraemic syndrome (aHUS) include HUS caused by defects in the regulation of alternative complement pathway and HUS linked to neuraminidase- producing pathogens, such as Streptococcus pneumoniae. Increasing data
Szilágyi, Ágnes
core  

PROTEOLYTIC PROCESSING OF VON WILLEBRAND FACTOR BY ADAMTS13 AND LEUKOCYTE PROTEASES-rev1-MJHID-2013

Mediterranean Journal of Hematology and Infectious Diseases, 2014
ADAMTS13 is a 190 kDa zinc protease encoded by a gene located on chromosome 9q34.   This protease specifically hydrolyzes von Willebrand factor (VWF) multimers, thus causing VWF size reduction.
Raimondo De Cristofaro
doaj  

Role of Extracellular Hemoglobin in Thrombosis and Vascular Occlusion in Patients with Sickle Cell Anemia

Anemia, 2011
Sickle cell anemia (SCA) is a common hemolytic disorder caused by a gene mutation in the β-globin subunit of hemoglobin (Hb) and affects millions of people.
Zhou Zhou, Molly Behymer, Prasenjit Guchhait   +2 more
doaj   +1 more source

Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom [PDF]

, 2010
,, Goodship, Tim H J, Machin, Sam, Taylor, C Mark, Wigmore, Stephen J   +4 more
core   +1 more source

Púrpura trombocitopênica trombótica: o papel do fator von Willebrand e da ADAMTS13 Thrombotic thrombocytopenic purpura: the role of von Willebrand factor and ADAMTS13

Revista Brasileira de Hematologia e Hemoterapia, 2010
A púrpura trombocitopênica trombótica (PTT) instala-se de modo abrupto e é caracterizada pela oclusão difusa de arteríolas e capilares da microcirculação, levando à isquemia de tecidos.
Leandro C. Tonaco, Danyelle R. A. Rios, Lauro M. Vieira, Maria das Graças Carvalho, Luci M. S. Dusse   +4 more
doaj