Results 91 to 100 of about 5,085,110 (360)
Major components of fish immunity: a review [PDF]
, 2016 Fish are fascinating creatures with a certain degree of immunity comparable to those of mammals. The fish's immune system consists of two major components, innate and adaptive immunities.
Nawi, Mohd Firdaus, Saad, Mohd Zamri
core
Human natural killer cells mediate adaptive immunity to viral antigens
Science immunology, 2019 Vaccination or childhood infection elicits antigen-specific, long-lived immunological memory in human natural killer cells. Recall responses by human NK cells One of the traditional dividing lines separating innate and adaptive immunity was the ...
Rana Nikzad +13 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
A Zebrafish Model of Mycobacterium leprae Granulomatous Infection. [PDF]
, 2017 Understanding the pathogenesis of leprosy granulomas has been hindered by a paucity of tractable experimental animal models. Mycobacterium leprae, which causes leprosy, grows optimally at approximately 30°C, so we sought to model granulomatous disease in
Cameron, James +2 more
core +2 more sources
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
MHC class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity [PDF]
, 2014 Background—Plasmacytoid dendritic cells (pDCs) bridge innate and adaptive immune responses and are important regulators of immuno-inflammatory diseases. However, their role in atherosclerosis remains elusive.
Ait-Oufella, Hafid +16 more
core +2 more sources
The IFITM protein family in adaptive immunity
Immunology, 2019 Interferon‐inducible transmembrane (IFITM) proteins are a family of small homologous proteins, localized in the plasma and endolysosomal membranes, which confer cellular resistance to many viruses.
Diana C. Yánez, Susan Ross, T. Crompton
semanticscholar +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Innate and adaptive immunity in teleost fish: a review.
, 2018 The immune system of fish is very similar to vertebrates, although there are some important dif - ferences. Fish are free-living organisms from the embryonic stage of life in their aquatic environment.
C. Uribe +3 more
semanticscholar +1 more source
LncRNAs in adaptive immunity: role in physiological and pathological conditions
RNA Biology, 2020 The adaptive immune system is responsible for generating immunological response and immunological memory. Regulation of adaptive immunity including B cell and T cell biology was mainly understood from the protein and microRNA perspective.
P. F. Zeni, M. Mraz
semanticscholar +1 more source