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NKG2C Improves Diagnostic Specificity of NK Cell Receptor Restriction by Identifying Non-Neoplastic Adaptive NK Cell Clones

ABSTRACT Natural killer (NK) cell neoplasms are a diverse group of entities with often nonspecific clinical presentations, making immunophenotyping essential for diagnosis. Immunophenotyping by flow cytometry can identify clonal NK cell populations by detecting restricted expression patterns of NK cell receptors such ...
Aaron J. Wilk, Gary Gitana, Jean Oak
openaire   +2 more sources

Investigating NK cell diversity in colorectal cancer: a role for adaptive NK cells in immunotherapeutic strategies

Natural killer (NK) cells are cytotoxic innate lymphocytes that play a central role in immune surveillance against malignant transformation through the integration of activating and inhibitory receptor signals. Their phenotype and function can be reshaped by inflammatory conditions, viral exposure, and tissue-specific microenvironments.
openaire   +1 more source

Natural Killer Cells: From Innate to Adaptive Features

Annual Review of Immunology, 2021
Joseph Sun, Rebecca Delconte
exaly  

Adaptation of non-immunogenic tumours to NK cells

European Journal of Cancer and Clinical Oncology, 1983
M. Zőller, S. Matzku
openaire   +1 more source

How Can We Improve the Vaccination Response in Older People? Part II: Targeting Immunosenescence of Adaptive Immunity Cells

International Journal of Molecular Sciences, 2022
Hugo Arasanz   +2 more
exaly  

NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells

Nature, 2012
Ann Haberman   +2 more
exaly  

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