Results 191 to 200 of about 26,788 (222)

Epithelial Gab1 Restricts Sepsis-Induced Intestinal Injury by Orchestrating TNF/NF-κB Axis. [PDF]

open access: yesMediators Inflamm
Jin W   +8 more
europepmc   +1 more source

Analysis of genes involved in immune response in children with HLH - case series. [PDF]

open access: yesPediatr Rheumatol Online J
Gowin E   +2 more
europepmc   +1 more source

TL1A serves as a positive regulator to promote adipocyte differentiation. [PDF]

open access: yesPLoS One
Chang Z   +6 more
europepmc   +1 more source

Signal-transducing adaptor protein-2 regulates macrophage migration into inflammatory sites during dextran sodium sulfate induced colitis

open access: yesSignal-transducing adaptor protein-2 regulates macrophage migration into inflammatory sites during dextran sodium sulfate induced colitis
openaire  

Graft-versus-host disease develops in mice transplanted with lymphocyte-depleted bone marrow cells from signal-transducing adaptor protein-2 transgenic mice

open access: yesGraft-versus-host disease develops in mice transplanted with lymphocyte-depleted bone marrow cells from signal-transducing adaptor protein-2 transgenic mice
openaire  

Graft-versus-host disease develops in mice transplanted with lymphocyte-depleted bone marrow cells from signal-transducing adaptor protein-2 transgenic mice

Biochemical and Biophysical Research Communications, 2021
Graft-versus-host disease (GVHD) is the most frequent complication after allogeneic hematopoietic stem cell transplantation (HSCT), and is one of the major causes of non-relapse mortality. Transferred mature lymphocytes are thought to be responsible for GVHD based on the findings that mice transplanted with lymphocyte-depleted bone marrow (BM) cells ...
Hideaki Saito   +13 more
openaire   +2 more sources

Signal‐transducing adaptor protein‐2 regulates macrophage migration into inflammatory sites during dextran sodium sulfate induced colitis

European Journal of Immunology, 2014
Signal‐transducing adaptor protein‐2 (STAP‐2) was cloned as a c‐fms/M‐CSF receptor interacting protein. STAP‐2 is an adaptor protein carrying pleckstrin homology and Src homology 2 like domains, as well as a YXXQ motif. STAP‐2 has been indicated to have an ability to bind and modulate a variety of signaling and transcriptional molecules.
Natsuko, Fujita   +12 more
openaire   +2 more sources

Role of Signal-Transducing Adaptor Protein-1 for T Cell Activation and Pathogenesis of Autoimmune Demyelination and Airway Inflammation

The Journal of Immunology
Abstract Signal-transducing adaptor protein (STAP)-1 is an adaptor protein that is widely expressed in T cells. In this article, we show that STAP-1 upregulates TCR-mediated T cell activation and T cell–mediated airway inflammation. Using STAP-1 knockout mice and STAP-1–overexpressing Jurkat cells, we found that STAP-1 enhanced TCR ...
Kota Kagohashi   +14 more
openaire   +2 more sources

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