Results 31 to 40 of about 44,969 (289)
Mathematical Biosciences and Engineering, 2023 To date, few studies have investigated whether the RNA-editing enzymes adenosine deaminases acting on RNA (ADARs) influence RNA functioning in lung adenocarcinoma (LUAD).
Siqi Hu +3 more
doaj +1 more source
Adenosine Deaminase Acting on RNA (ADAR) Enzymes: A Journey from Weird to Wondrous
Accounts of Chemical Research, 2023 Conspectus The adenosine deaminase acting on RNA (ADAR) enzymes that catalyze the conversion of adenosine to inosine in double-stranded (ds)RNA are evolutionarily conserved and are essential for many biological functions including nervous system function,
L. Keegan +2 more
semanticscholar +1 more source
Identification of the pathogenic variants in three Chinese families with dyschromatosis symmetrica hereditaria [PDF]
Jichu yixue yu linchuang, 2023 Objective To analyze the clinical features and to identify the pathogenic variants in three Chinese families with dyschromatosis symmetrica hereditaria (DSH).
YANG Xueting, GUO Kexin, SUN Yang, WANG Rongrong, MA Donglai, ZHANG Xue
doaj +1 more source
ADAR, the carcinogenesis mechanisms of ADAR and related clinical applications [PDF]
Annals of Translational Medicine, 2019 Adenosine deaminases acting on RNA (ADARs) catalyze the conversion of adenosine (A) to inosine (I) in double-stranded RNA, which can change the codons after transcription. Abnormal ADAR editing is present in a variety of cancers. However, the study of the biological effects of ADARs in cancer is not very deep.
Wen Gao, Yue Zhang, Jing Xu, Huizhu Qian
openaire +3 more sources
ANALYSIS OF FAST NEUTRON TRANSPORT IN CHLORIDE SALTS USING MONTE CARLO METHOD
Acta Polytechnica CTU Proceedings, 2020 The aim of this paper is to present results of fast neutron behavior analysis within the chloride salts environment using simulations based on Monte Carlo method (MCNP 6.2).
Ondřej Šťastný +4 more
doaj +1 more source
Non-rational Narain CFTs from codes over $F_4$ [PDF]
High Energ. Phys. 2021, 16 (2021), 2021 We construct a map between a class of codes over $F_4$ and a family of non-rational Narain CFTs. This construction is complementary to a recently introduced relation between quantum stabilizer codes and a class of rational Narain theories. From the modular bootstrap point of view we formulate a polynomial ansatz for the partition function which reduces
arxiv +1 more source
ADAR expression and copy number variation in patients with advanced gastric cancer
BMC Gastroenterology, 2020 Background Gastric cancer (GC) is a world health problem and it is the third leading cause of cancer deaths worldwide. The current practice for prognosis assessment in GC is based on radiological and pathological criteria and they may not result in an ...
Javad Behroozi +3 more
doaj +1 more source
The A to I editing landscape in melanoma and its relation to clinical outcome
RNA Biology, 2022 RNA editing refers to non-transient RNA modifications that occur after transcription and prior to translation by the ribosomes. RNA editing is more widespread in cancer cells than in non-transformed cells and is associated with tumorigenesis of various ...
Austeja Amweg +11 more
doaj +1 more source
Evaluation of the Interplay between the ADAR Editome and Immunotherapy in Melanoma [PDF]
Non-Coding RNA, 2021 Background: RNA editing is a highly conserved posttranscriptional mechanism that contributes to transcriptome diversity. In mammals, it includes nucleobase deaminations that convert cytidine (C) into uridine (U) and adenosine (A) into inosine (I).
Steve Pascolo +11 more
openaire +6 more sources
Squid express conserved ADAR orthologs that possess novel features
Frontiers in Genome Editing, 2023 The coleoid cephalopods display unusually extensive mRNA recoding by adenosine deamination, yet the underlying mechanisms are not well understood. Because the adenosine deaminases that act on RNA (ADAR) enzymes catalyze this form of RNA editing, the ...
Isabel C. Vallecillo-Viejo +5 more
semanticscholar +1 more source