Results 21 to 30 of about 14,644 (161)

Dynamic hyper-editing underlies temperature adaptation in Drosophila. [PDF]

PLoS Genetics, 2017
In Drosophila, A-to-I editing is prevalent in the brain, and mutations in the editing enzyme ADAR correlate with specific behavioral defects. Here we demonstrate a role for ADAR in behavioral temperature adaptation in Drosophila.
Ilana Buchumenski, Osnat Bartok, Reut Ashwal-Fluss, Varun Pandey, Hagit T Porath, Erez Y Levanon, Sebastian Kadener   +6 more
doaj   +1 more source

tlhagan/ADAR: ADAR RNAseq Analysis

, 2023
Analysis of RNAseq data from CD11c ADAR1 KO ...
tlhagan
core   +1 more source

Probing ADAR-RNA Interactions for the Rational Design of Human ADAR Family-Specific Modulators [PDF]

, 2023
An important class of enzymes involved in RNA editing is the ADAR family (adenosine deaminases acting on RNA), which facilitate the deamination of adenosine (A) to inosine (I) in double-stranded RNA (dsRNA). Inosines are decoded as guanosines (G) in most
Mendoza, Herra Grajo
core   +1 more source

Prioritizing of industrial wastewater management processes using an integrated AHP–CoCoSo model: comparative and sensitivity analyses

, 2021
The increase in individuals’ consumption and needs and the rapid development of technology result in different types of industrial wastewaters. A vast majority of industrial wastewaters are harmful to humans and other animals, as well as the environment.
Adar, Tuba, Adar, Elanur, Delice, Elif Kılıç   +2 more
core   +1 more source

Effect of Polypropylene Fiber on Workability and High Temperature Resistance of Self-Compacting Concrete [PDF]

, 2020
Konvansiyonel betona kıyasla yüksek işlenebilirlik, düşük işçilik maliyeti ve yüksek dayanım gibi avantajlar sağlayan kendiliğinden yerleşen beton (KYB) yüksek performanslıdır.
Adar, Muhammet, Bingöl, Ahmet Ferhat, Adar, Elanur   +2 more
core   +1 more source

Programmable RNA editing with endogenous ADAR enzymes – a feasible option for the treatment of inherited retinal disease?

Frontiers in Molecular Neuroscience, 2023
RNA editing holds great promise for the therapeutic correction of pathogenic, single nucleotide variants (SNV) in the human transcriptome since it does not risk creating permanent off-targets edits in the genome and has the potential for innovative ...
Julia-Sophia Bellingrath, Michelle E. McClements, M. Dominik Fischer, M. Dominik Fischer, Robert E. MacLaren, Robert E. MacLaren   +5 more
doaj   +1 more source

Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy

BMC Biology, 2020
Background In fly brains, the Drosophila Adar (adenosine deaminase acting on RNA) enzyme edits hundreds of transcripts to generate edited isoforms of encoded proteins.
Anzer Khan, Simona Paro, Leeanne McGurk, Nagraj Sambrani, Marion C. Hogg, James Brindle, Giuseppa Pennetta, Liam P. Keegan, Mary A. O’Connell   +8 more
doaj   +1 more source

ADAR Expression and Single Nucleotide Variants in Multiple Sclerosis Patients Affect the Response to Interferon Beta Therapy

Global Medical Genetics, 2023
Interferon (IFN)-β is the first-line disease management choice in multiple sclerosis (MS) with profound effects; however, in up to 50% of patients, clinical response does not occur.
Fakhr Fakhr, Shaygannejad Shaygannejad, Khorrami Khorrami, Saberi Saberi, Mirmosayyeb Mirmosayyeb, Sadeghi Sadeghi, Kheirollahi Kheirollahi   +6 more
doaj   +1 more source

Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome

Cell Reports, 2015
Little is known about how RNA editing operates in cancer. Transcriptome analysis of 68 normal and cancerous breast tissues revealed that the editing enzyme ADAR acts uniformly, on the same loci, across tissues.
Debora Fumagalli, David Gacquer, Françoise Rothé, Anne Lefort, Frederick Libert, David Brown, Naima Kheddoumi, Adam Shlien, Tomasz Konopka, Roberto Salgado, Denis Larsimont, Kornelia Polyak, Karen Willard-Gallo, Christine Desmedt, Martine Piccart, Marc Abramowicz, Peter J. Campbell, Christos Sotiriou, Vincent Detours   +18 more
doaj   +1 more source

Removal of acid yellow 17 from textile wastewater by adsorption and heterogeneous persulfate oxidation [PDF]

, 2020
Azo dyes commonly used in various industries have a stable and toxic structure. Wastewater containing AY17 dye as a model contaminant was investigated in terms of color and COD removal by both adsorption and persulfate oxidation activated with the PAC ...
Adar, Elanur
core   +1 more source