Results 31 to 40 of about 42,435 (206)
Adenosine to inosine editing by ADAR2 requires formation of a ternary complex on the GluR-B R/G site [PDF]
, 2002 RNA editing by members of the ADAR (adenosine deaminase that acts on RNA) enzyme family involves hydrolytic deamination of adenosine to inosine within the context of a double-stranded pre-mRNA substrate.
Collins, Cynthia H. +2 more
core +1 more source
Prediction of scientific collaborations through multiplex interaction networks [PDF]
, 2020 Link prediction algorithms can help to understand the structure and dynamics of scientific collaborations and the evolution of Science. However, available algorithms based on similarity between nodes of collaboration networks are bounded by the limited ...
Aleta, Alberto +4 more
core +4 more sources
Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome
Cell Reports, 2015 Little is known about how RNA editing operates in cancer. Transcriptome analysis of 68 normal and cancerous breast tissues revealed that the editing enzyme ADAR acts uniformly, on the same loci, across tissues.
Debora Fumagalli +18 more
doaj +1 more source
Reciprocal regulation of A-to-I RNA editing and the vertebrate nervous system [PDF]
, 2013 The fine control of molecules mediating communication in the nervous system is key to adjusting neuronal signaling during development and in maintaining the stability of established networks in the face of altered sensory input.
Ales eBalik +3 more
core +2 more sources
Promoting RNA editing by ADAR attraction [PDF]
Genome Biology, 2017 Concentration is important and not only while driving; a new study indicates how an adjacent genomic element helps to increase the efficiency of a specific adenosine to inosine RNA editing reaction, by providing a means to increase the local concentration of the RNA editing enzyme ADAR.
Miri Danan-Gotthold, Erez Y. Levanon
openaire +3 more sources
RNA Biology, 2023 Adenosine-to-inosine (A-to-I) RNA editing, mediated by metazoan ADAR enzymes, is a prevalent post-transcriptional modification that diversifies the proteome and promotes adaptive evolution of organisms. The Drosophila Adar gene has an auto-recoding site (
Ling Ma +8 more
doaj +1 more source
Viruses, 2023 The Adenosine Deaminases Acting on RNA (ADAR) catalyze the posttranscriptional deamination of adenosine residues to inosine in double-stranded RNAs (dsRNAs, A-to-I editing), preventing the overactivation of dsRNA sensor molecules and interferons.
Vlatka Ivanišević +5 more
doaj +1 more source
Monitoring Challenges and Approaches for P2P File-Sharing Systems [PDF]
, 2006 Since the release of Napster in 1999, P2P file-sharing has enjoyed a dramatic rise in popularity. A 2000 study by Plonka on the University of Wisconsin campus network found that file-sharing accounted for a comparable volume of traffic to HTTP, while a ...
Hughes, D., Lee, K., Walkerdine, J.
core +2 more sources
ADAR Editing Wobbles the MicroRNA World [PDF]
ACS Chemical Biology, 2007 Recent work reveals that adenosine-to-inosine editing occurs in a number of cellular microRNAs (miRNAs). Such editing is shown to diminish the expression of one miRNA and alter the target specificity of another. This changes our current views significantly by not only increasing the repertoire of miRNAs and their potential targets, but also providing ...
Asis K, Das, Gordon G, Carmichael
openaire +2 more sources
Integrating the physical environment into Alzheimer's disease and Alzheimer's disease related dementias research: A Gateway Exposome Coordinating Center (GECC) agenda on gaps and priorities [PDF]
Alzheimers DementAbstract The physical environment is an important yet underexplored domain in Alzheimer's disease and Alzheimer's disease and related dementias (AD/ADRD), shaping exposures and health‐related behaviors across the life course. We identified key gaps and priorities for incorporating physical environment measures into population‐based research, with an ...
Doiron D +16 more
europepmc +2 more sources