Results 31 to 40 of about 14,644 (161)
New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins
Biomolecules, 2015 The ADAR proteins deaminate adenosine to inosine in double-stranded RNA which is one of the most abundant modifications present in mammalian RNA.
Niamh Mannion +4 more
doaj +1 more source
RNA Biology, 2023 Adenosine-to-inosine (A-to-I) RNA editing, mediated by metazoan ADAR enzymes, is a prevalent post-transcriptional modification that diversifies the proteome and promotes adaptive evolution of organisms. The Drosophila Adar gene has an auto-recoding site (
Ling Ma +8 more
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Viruses, 2023 The Adenosine Deaminases Acting on RNA (ADAR) catalyze the posttranscriptional deamination of adenosine residues to inosine in double-stranded RNAs (dsRNAs, A-to-I editing), preventing the overactivation of dsRNA sensor molecules and interferons.
Vlatka Ivanišević +5 more
doaj +1 more source
Characterising new roles for APOBEC4 and ADAR deaminases [PDF]
, 2010 Deamination or the hydrolytic removal of one hydroxyl group from a base in DNA or RNA can lead to changes in the transcript and protein produced. Examples of this are the deamination of cytosine residues in DNA by activation induced deaminase (AID ...
Hogg, Marion
core +4 more sources
, 2021 With the increasing population, the amount of wastewater that needs to be managed is also increasing. Population growth also increases energy demand. While treating wastewater containing organic matter and water, hydrogen energy can be produced at the ...
Adar, Elanur
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All I's on the
, 2018 Adenosine to inosine (A‐to‐I) editing is the most abundant form of RNA modification in mammalian cells, which is catalyzed by adenosine deaminase acting on the double‐stranded RNA (ADAR) protein family. A‐to‐I editing is currently known to be involved in
Galina Shevchenko +3 more
core +1 more source
Proteini ADAR u bolestima ljudi
, 2020 Adenosine deaminase acting on RNA (ADAR) is a mammalian protein family, consisting of five enzymes out of which ADAR1 and ADAR2 possess catalytic activity. Their mechanism of action, called A-to-I (adenosine-to-inosine) editing, is a post-transcriptional
Neuberg, Dorotea
core +1 more source
PLoS ONE, 2023 Parkinson's Disease (PD) is the second most common neurodegenerative disease behind Alzheimer's Disease, currently affecting more than 10 million people worldwide and 1.5 times more males than females.
Heather Milliken Mercer +3 more
doaj +1 more source
Extending adamic adar for cold-start problem in link prediction based on network metrics
IJAIN (International Journal of Advances in Intelligent Informatics), 2022 The cold-start problem is a condition for a new node to join a network with no available information or an isolated node. Most studies use topological network information with the Triadic Closure principles to predict links in future networks.
Herman Yuliansyah +2 more
doaj +1 more source
Unveiling RNA Editing by ADAR and APOBEC Protein Gene Families
Frontiers in Bioscience-LandmarkRNA editing is a crucial post-transcriptional modification that alters the transcriptome and proteome and affects many cellular processes, including splicing, microRNA specificity, stability of RNA molecules, and protein structure.
Alexander Modestov +2 more
doaj +1 more source