Results 61 to 70 of about 42,221 (215)
Fragile X syndrome (FXS) is the most frequent inherited form of mental retardation. The cause for this X-linked disorder is the silencing of the fragile X mental retardation 1 (fmr1) gene and the absence of the fragile X mental retardation protein (Fmrp).
Adi Shamay-Ramot +10 more
doaj +1 more source
Automated data acquisition and reduction system for torsional braid analyzer [PDF]
Automated Data Acquisition and Reduction System (ADAR) evaluates damping coefficient and relative rigidity by storing four successive peaks of waveform and time period between two successive peaks.
Carl, G. L. +3 more
core +1 more source
Personalized Degrees: Effects on Link Formation in Dynamic Networks from an Egocentric Perspective
Understanding mechanisms driving link formation in dynamic social networks is a long-standing problem that has implications to understanding social structure as well as link prediction and recommendation.
Arastuie, Makan, Xu, Kevin S.
core +1 more source
Improved arrayed-waveguide-grating layout avoiding systematic phase errors [PDF]
We present a detailed description of an improved arrayed-waveguide-grating (AWG) layout for both, low and high diffraction orders. The novel layout presents identical bends across the entire array; in this way systematic phase errors arising from ...
Driessen, Alfred +6 more
core +4 more sources
ABSTRACT From its very inception, the Jewish National Movement Hibbat Zion turned to the collective past to advance its goals in the present. One of their activities was to reinterpret Jewish holidays and festivals, especially those that did not take a central place in the Jewish calendar.
Asaf Yedidya
wiley +1 more source
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang +18 more
wiley +1 more source
Altered ADAR 2 equilibrium and 5HT2CR editing in the prefrontal cortex of ADAR 2 transgenic mice [PDF]
Modulation of serotonin signaling by RNA editing of the serotonin 2C receptor (5HT(2C) R) may be relevant to affective disorder as serotonin functions regulate mood and behavior. Previously, we observed enhanced endogenous behavioral despair in ADAR2 transgenic mice.
M, Singh +5 more
openaire +2 more sources
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang +11 more
wiley +1 more source
ADARs: Viruses and Innate Immunity [PDF]
Double-stranded RNA (dsRNA) functions both as a substrate of ADARs and also as a molecular trigger of innate immune responses. ADARs, adenosine deaminases that act on RNA, catalyze the deamination of adenosine (A) to produce inosine (I) in dsRNA. ADARs thereby can destablize RNA structures, because the generated I:U mismatch pairs are less stable than ...
openaire +2 more sources
Multi‐Tissue Genetic Regulation of RNA Editing in Pigs
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan +21 more
wiley +1 more source

