Results 61 to 70 of about 42,221 (215)

Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in Zebrafish.

open access: yesPLoS Genetics, 2015
Fragile X syndrome (FXS) is the most frequent inherited form of mental retardation. The cause for this X-linked disorder is the silencing of the fragile X mental retardation 1 (fmr1) gene and the absence of the fragile X mental retardation protein (Fmrp).
Adi Shamay-Ramot   +10 more
doaj   +1 more source

Automated data acquisition and reduction system for torsional braid analyzer [PDF]

open access: yes, 1975
Automated Data Acquisition and Reduction System (ADAR) evaluates damping coefficient and relative rigidity by storing four successive peaks of waveform and time period between two successive peaks.
Carl, G. L.   +3 more
core   +1 more source

Personalized Degrees: Effects on Link Formation in Dynamic Networks from an Egocentric Perspective

open access: yes, 2019
Understanding mechanisms driving link formation in dynamic social networks is a long-standing problem that has implications to understanding social structure as well as link prediction and recommendation.
Arastuie, Makan, Xu, Kevin S.
core   +1 more source

Improved arrayed-waveguide-grating layout avoiding systematic phase errors [PDF]

open access: yes, 2011
We present a detailed description of an improved arrayed-waveguide-grating (AWG) layout for both, low and high diffraction orders. The novel layout presents identical bends across the entire array; in this way systematic phase errors arising from ...
Driessen, Alfred   +6 more
core   +4 more sources

The National Transformation of the Historical Memory of Minor Jewish Holidays During the Period of Hibbat Zion

open access: yesStudies in Ethnicity and Nationalism, EarlyView.
ABSTRACT From its very inception, the Jewish National Movement Hibbat Zion turned to the collective past to advance its goals in the present. One of their activities was to reinterpret Jewish holidays and festivals, especially those that did not take a central place in the Jewish calendar.
Asaf Yedidya
wiley   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang   +18 more
wiley   +1 more source

Altered ADAR 2 equilibrium and 5HT2CR editing in the prefrontal cortex of ADAR 2 transgenic mice [PDF]

open access: yesGenes, Brain and Behavior, 2011
Modulation of serotonin signaling by RNA editing of the serotonin 2C receptor (5HT(2C) R) may be relevant to affective disorder as serotonin functions regulate mood and behavior. Previously, we observed enhanced endogenous behavioral despair in ADAR2 transgenic mice.
M, Singh   +5 more
openaire   +2 more sources

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

open access: yesAdvanced Science, Volume 13, Issue 18, 27 March 2026.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang   +11 more
wiley   +1 more source

ADARs: Viruses and Innate Immunity [PDF]

open access: yes, 2011
Double-stranded RNA (dsRNA) functions both as a substrate of ADARs and also as a molecular trigger of innate immune responses. ADARs, adenosine deaminases that act on RNA, catalyze the deamination of adenosine (A) to produce inosine (I) in dsRNA. ADARs thereby can destablize RNA structures, because the generated I:U mismatch pairs are less stable than ...
openaire   +2 more sources

Multi‐Tissue Genetic Regulation of RNA Editing in Pigs

open access: yesAdvanced Science, Volume 13, Issue 17, 23 March 2026.
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan   +21 more
wiley   +1 more source

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