Generation of two iPSC lines from patients with Aicardi-Goutières syndrome carrying either biallelic ADAR1 mutations (PC138) or a heterozygous IFIH1 mutation (PC139). [PDF]
Zerad L +11 more
europepmc +1 more source
Deaminase Modulation Driving a New Era in Drug Development. [PDF]
Lindley RA.
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Epitranscriptome-wide profiling identifies RNA editing events regulated by ADAR1 that are associated with DNA repair mechanisms in human TK6 cells. [PDF]
Yoshida A +8 more
europepmc +1 more source
Innate immune recognition and evasion strategies of hepatitis B virus: from DNA to RNA and viral proteins. [PDF]
Chen Z +8 more
europepmc +1 more source
PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer. [PDF]
Young AA +10 more
europepmc +1 more source
MYC drives left-handed Z-DNA formation to shape gene expression. [PDF]
Wan X +10 more
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Cromolyn as a novel pharmacophore of the Zα domain of the RNA-editing enzyme ADAR1p150. [PDF]
Langdon N +7 more
europepmc +1 more source
Clinical insight-driven novel drug development: Multidisciplinary integration and transformative opportunities. [PDF]
Li B, Xu H, Shi X, Ma C, Yang J, Zhan P.
europepmc +1 more source
A hepatitis B virus RNA-sensing and RNA-editing-dependent reporter system. [PDF]
Sun L, Snedeker A, Tang L.
europepmc +1 more source
Mouse models of type I interferonopathies. [PDF]
Luca D, Kato H.
europepmc +1 more source

